日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Modeling common Alzheimer's disease with high and low polygenic risk in human iPSC: A large-scale research resource.

利用人类 iPSC 模拟具有高低多基因风险的常见阿尔茨海默病:大规模研究资源

Maguire Emily, Winston Jincy, Ellwood Sarah H, O'Donoghue Rachel, Shaw Bethany, Morales Atahualpa Castillo, Keat Samuel, Evans Alexandra, Marshall Rachel, Luckcuck Lauren, Brown Laura, Salis Elisa, Leonenko Ganna, Denning Nicola, Allen Nicholas D, Escott-Price Valentina, Webber Caleb, Taylor Philip R, Sims Rebecca, Cowley Sally A, Williams Julie, Carpanini Sarah M, Hall-Roberts Hazel

Anti-obesity compounds, Semaglutide and LiPR, and PrRP do not change the proportion of human and mouse POMC+ neurons.

抗肥胖化合物索马鲁肽和LiPR以及PrRP不会改变人类和小鼠POMC+神经元的比例

Jörgensen Sara K M, Surridge-Smith May, Jones Kimberley, Maletínská Lenka, Allen Nicholas D, Petrik David

Case Report: Right Insular Stroke Causing Simultaneous Onset of a Functional Vestibular Disorder and Psychiatric Disorder-Persistent Postural-Perceptual Dizziness and Post-stroke Depression

病例报告:右侧岛叶卒中同时导致功能性前庭功能障碍和精神障碍——持续性姿势性知觉性眩晕和卒中后抑郁症

Fipps, David C; Staab, Jeffrey P; Allen, Nicholas D

Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons

新型胎儿脑发育表观遗传时钟可预测细胞干细胞模型和衍生神经元的产前年龄

Steg, Leonard C; Shireby, Gemma L; Imm, Jennifer; Davies, Jonathan P; Franklin, Alice; Flynn, Robert; Namboori, Seema C; Bhinge, Akshay; Jeffries, Aaron R; Burrage, Joe; Neilson, Grant W A; Walker, Emma M; Perfect, Leo W; Price, Jack; McAlonan, Grainne; Srivastava, Deepak P; Bray, Nicholas J; Cope, Emma L; Jones, Kimberley M; Allen, Nicholas D; Pishva, Ehsan; Dempster, Emma L; Lunnon, Katie; Mill, Jonathan; Hannon, Eilis

Mirtazapine's effect on the QT interval in medically hospitalized patients

米氮平对住院患者QT间期的影响

Allen, Nicholas D; Leung, Jonathan G; Palmer, Brian A

Detrimental effect of zwitterionic buffers on lysosomal homeostasis in cell lines and iPSC-derived neurons

两性离子缓冲液对细胞系和iPSC衍生神经元溶酶体稳态的有害影响

Cook, Sophie R; Badell-Grau, Rafael A; Kirkham, Emily D; Jones, Kimberley M; Kelly, Brendan P; Winston, Jincy; Waller-Evans, Helen; Allen, Nicholas D; Lloyd-Evans, Emyr

Nucleosome dynamics of human iPSC during neural differentiation

人类诱导多能干细胞在神经分化过程中的核小体动力学

Harwood, Janet C; Kent, Nicholas A; Allen, Nicholas D; Harwood, Adrian J

Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease

基于HRC推断的全基因组关联数据的基因分析鉴定出三个与阿尔茨海默病相关的新基因

Baker, Emily; Sims, Rebecca; Leonenko, Ganna; Frizzati, Aura; Harwood, Janet C; Grozeva, Detelina; Morgan, Kevin; Passmore, Peter; Holmes, Clive; Powell, John; Brayne, Carol; Gill, Michael; Mead, Simon; Bossù, Paola; Spalletta, Gianfranco; Goate, Alison M; Cruchaga, Carlos; Maier, Wolfgang; Heun, Reinhard; Jessen, Frank; Peters, Oliver; Dichgans, Martin; FröLich, Lutz; Ramirez, Alfredo; Jones, Lesley; Hardy, John; Ivanov, Dobril; Hill, Matthew; Holmans, Peter; Allen, Nicholas D; Morgan, B Paul; Seshadri, Sudha; Schellenberg, Gerard D; Amouyel, Philippe; Williams, Julie; Escott-Price, Valentina

Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library

利用自分泌细胞筛选法,从组合抗体库中筛选出全人源TrkB激动剂抗体

Merkouris, Spyros; Barde, Yves-Alain; Binley, Kate E; Allen, Nicholas D; Stepanov, Alexey V; Wu, Nicholas C; Grande, Geramie; Lin, Chih-Wei; Li, Meng; Nan, Xinsheng; Chacon-Fernandez, Pedro; DiStefano, Peter S; Lindsay, Ronald M; Lerner, Richard A; Xie, Jia

Mutations in Grxcr1 are the basis for inner ear dysfunction in the pirouette mouse

Grxcr1基因突变是旋转小鼠内耳功能障碍的根本原因。

Odeh, Hana; Hunker, Kristina L; Belyantseva, Inna A; Azaiez, Hela; Avenarius, Matthew R; Zheng, Lili; Peters, Linda M; Gagnon, Leona H; Hagiwara, Nobuko; Skynner, Michael J; Brilliant, Murray H; Allen, Nicholas D; Riazuddin, Saima; Johnson, Kenneth R; Raphael, Yehoash; Najmabadi, Hossein; Friedman, Thomas B; Bartles, James R; Smith, Richard J H; Kohrman, David C