Directing fratricide within T cell products using an anti-uPAR chimeric antigen receptor to drive the production of potent therapeutic cells
利用抗uPAR嵌合抗原受体在T细胞产品中诱导同胞相残,从而驱动高效治疗细胞的产生
期刊:
影响因子:
doi:10.1101/2025.10.24.684419
Sarko, Lauren; Givand, David; Shepley, Claire; Rattin, Brendan; Attar, Allen; Taylor, Rachel; Kutler, Benjamin; Traynor, Roshini M; Upadhyaya, Anika; Mnuk, Mackenzie; Gehrke, Cavin; Murren, Nat; Ulland, Tyler K; Kotanchek, Theresa; Saha, Krishanu
信号转导
免疫/内分泌
细胞生物学
T细胞
uPAR
uPA
T细胞