日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IL-1ra and CCL5, but not IL-10, are promising targets for treating SMA astrocyte-driven pathology

IL-1ra 和 CCL5(而非 IL-10)是治疗 SMA 星形胶质细胞驱动病理的潜在靶点。

Reilly L Allison,Cecelia C Mangione,Mya Suneja,Jessica Gawrys,Brendan M Melvin,Natalya Belous,Megan LaCroix,Matthew Harmelink,Barrington G Burnett,Allison D Ebert

High mobility group box 1 (HMGB1) is a potential disease biomarker in cell and mouse models of Duchenne muscular dystrophy

高迁移率族蛋白 1 (HMGB1) 是杜氏肌营养不良症细胞和小鼠模型中的潜在疾病生物标志物

Rebecca A Slick, Jessica Sutton, Margaret Haberman, Benjamin S O'Brien, Jennifer A Tinklenberg, Aashay Mardikar, Mariah J Prom, Margaret Beatka, Melanie Gartz, Mark A Vanden Avond, Emily Siebers, David L Mack, J Patrick Gonzalez, Allison D Ebert, Kanneboyina Nagaraju, Michael W Lawlor

Stabilizing microtubules aids neurite structure and disrupts syncytia formation in human cytomegalovirus-infected human forebrain neurons

稳定微管有助于神经突结构并破坏人类巨细胞病毒感染的人类前脑神经元的合胞体形成

Jacob W Adelman, Andrew T Sukowaty, Kaitlyn J Partridge, Jessica E Gawrys, Scott S Terhune, Allison D Ebert

A spinal muscular atrophy modifier implicates the SMN protein in SNARE complex assembly at neuromuscular synapses

脊髓性肌萎缩症修饰因子表明SMN蛋白参与神经肌肉突触处SNARE复合物的组装。

Jeong-Ki Kim ,Narendra N Jha ,Tomoyuki Awano ,Charlotte Caine ,Kishore Gollapalli ,Emily Welby ,Seung-Soo Kim ,Andrea Fuentes-Moliz ,Xueyong Wang ,Zhihua Feng ,Fusako Sera ,Taishi Takeda ,Shunichi Homma ,Chien-Ping Ko ,Lucia Tabares ,Allison D Ebert ,Mark M Rich ,Umrao R Monani

Human cytomegalovirus induces significant structural and functional changes in terminally differentiated human cortical neurons

人类巨细胞病毒诱导终末分化的人类皮质神经元发生显著的结构和功能变化

Jacob W Adelman, Suzette Rosas-Rogers, Megan L Schumacher, Rebekah L Mokry, Scott S Terhune, Allison D Ebert

Viral vector gene delivery of the novel chaperone protein SRCP1 to modify insoluble protein in in vitro and in vivo models of ALS

病毒载体基因传递新型伴侣蛋白 SRCP1 来修饰 ALS 体外和体内模型中的不溶性蛋白质

Ian W Luecke #, Gloria Lin #, Stephanie Santarriaga, K Matthew Scaglione, Allison D Ebert

Human Cytomegalovirus Induces Significant Structural and Functional Changes in Terminally Differentiated Human Cortical Neurons

人类巨细胞病毒诱导终末分化的人类皮质神经元发生显著的结构和功能变化

Jacob W Adelman, Suzette Rosas-Rogers, Megan L Schumacher, Rebekah L Mokry, Scott S Terhune, Allison D Ebert

Mitigating aberrant Cdk5 activation alleviates mitochondrial defects and motor neuron disease symptoms in spinal muscular atrophy

减轻异常 Cdk5 激活可减轻脊髓性肌萎缩症中的线粒体缺陷和运动神经元疾病症状

Nimrod Miller #, Zhaofa Xu #, Katharina A Quinlan, Amy Ji, Jered V McGivern, Zhihua Feng, Han Shi, Chien-Ping Ko, Li-Huei Tsai, Charles J Heckman, Allison D Ebert, Yongchao C Ma

Viral mediated knockdown of GATA6 in SMA iPSC-derived astrocytes prevents motor neuron loss and microglial activation

病毒介导敲低 SMA iPSC 衍生的星形胶质细胞中的 GATA6 可防止运动神经元丢失和小胶质细胞活化

Reilly L Allison, Emily Welby, Guzal Khayrullina, Barrington G Burnett, Allison D Ebert

Downregulation of neurodevelopmental gene expression in iPSC-derived cerebral organoids upon infection by human cytomegalovirus

人巨细胞病毒感染后,iPSC衍生脑类器官中神经发育基因表达下调

Benjamin S O'Brien ,Rebekah L Mokry ,Megan L Schumacher ,Kirthi Pulakanti ,Sridhar Rao ,Scott S Terhune ,Allison D Ebert