日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Fresolimumab treatment decreases biomarkers and improves clinical symptoms in systemic sclerosis patients

Fresolimumab 治疗可降低系统性硬化症患者的生物标志物并改善临床症状

Lisa M Rice, Cristina M Padilla, Sarah R McLaughlin, Allison Mathes, Jessica Ziemek, Salma Goummih, Sashidhar Nakerakanti, Michael York, Giuseppina Farina, Michael L Whitfield, Robert F Spiera, Romy B Christmann, Jessica K Gordon, Janice Weinberg, Robert W Simms, Robert Lafyatis

Thymic stromal lymphopoietin is up-regulated in the skin of patients with systemic sclerosis and induces profibrotic genes and intracellular signaling that overlap with those induced by interleukin-13 and transforming growth factor β

胸腺基质淋巴细胞生成素在系统性硬化症患者的皮肤中上调,并诱导促纤维化基因和细胞内信号传导,这些基因和信号传导与白细胞介素-13 和转化生长因子 β 诱导的基因和细胞内信号传导重叠

Romy B Christmann, Allison Mathes, Alsya J Affandi, Cristina Padilla, Banafsheh Nazari, Andreea M Bujor, Giuseppina Stifano, Robert Lafyatis