日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inhibitors of the Hippo Pathway Kinases STK3/MST2 and STK4/MST1 Have Utility for the Treatment of Acute Myeloid Leukemia

Hippo 通路激酶 STK3/MST2 和 STK4/MST1 抑制剂可用于治疗急性髓系白血病

Nicole Bata, Apirat Chaikuad, Nicole A Bakas, Allison S Limpert, Lester J Lambert, Douglas J Sheffler, Lena M Berger, Guoxiong Liu, Cunxiang Yuan, Li Wang, Yi Peng, Jing Dong, Maria Celeridad, Fabiana Layng, Stefan Knapp, Nicholas D P Cosford

Development and use of a high-throughput screen to identify novel modulators of the corticotropin releasing factor binding protein

开发和使用高通量筛选来识别促皮质素释放因子结合蛋白的新型调节剂

Carolina L Haass-Koffler, T Chase Francis, Pauravi Gandhi, Reesha Patel, Mohammad Naemuddin, Carsten K Nielsen, Selena E Bartlett, Antonello Bonci, Stefan Vasile, Becky L Hood, Eigo Suyama, Michael P Hedrick, Layton H Smith, Allison S Limpert, Marisa Roberto, Nicholas D P Cosford, Douglas J Sheffler

Design, Synthesis, and Characterization of an Orally Active Dual-Specific ULK1/2 Autophagy Inhibitor that Synergizes with the PARP Inhibitor Olaparib for the Treatment of Triple-Negative Breast Cancer

设计、合成和表征一种口服活性双特异性ULK1/2自噬抑制剂,该抑制剂与PARP抑制剂奥拉帕尼具有协同作用,用于治疗三阴性乳腺癌

Huiyu Ren ,Nicole A Bakas ,Mitchell Vamos ,Apirat Chaikuad ,Allison S Limpert ,Carina D Wimer ,Sonja N Brun ,Lester J Lambert ,Lutz Tautz ,Maria Celeridad ,Douglas J Sheffler ,Stefan Knapp ,Reuben J Shaw ,Nicholas D P Cosford

Benzodiazepinone derivatives protect against endoplasmic reticulum stress-mediated cell death in human neuronal cell lines

苯二氮卓酮衍生物可防止人类神经元细胞系中内质网应激介导的细胞死亡

Haixia Zou, Allison S Limpert, Jiwen Zou, Anna Dembo, Pooi-San Lee, Daniel Grant, Robert Ardecky, Anthony B Pinkerton, Gavin K Magnuson, Mark E Goldman, Juan Rong, Peter Teriete, Douglas J Sheffler, John C Reed, Nicholas D P Cosford

NF-κB forms a complex with the chromatin remodeler BRG1 to regulate Schwann cell differentiation

NF-κB 与染色质重塑剂 BRG1 形成复合物,调节雪旺细胞分化

Allison S Limpert, Shujun Bai, Malathi Narayan, Jiang Wu, Sung Ok Yoon, Bruce D Carter, Q Richard Lu

Axonal neuregulin 1 type III activates NF-kappaB in Schwann cells during myelin formation

轴突神经调节蛋白 1 III 型在髓鞘形成过程中激活雪旺细胞中的 NF-κB

Allison S Limpert, Bruce D Carter