日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Tumor Integrin-Targeted Glucose Oxidase Enzyme Promotes ROS-Mediated Cell Death that Combines with Interferon Alpha Therapy for Tumor Control

肿瘤整合素靶向葡萄糖氧化酶促进ROS介导的细胞死亡,可与干扰素α疗法联合用于肿瘤控制

Jordan A Stinson ,Allison Sheen ,Brianna M Lax ,Grace N Yang ,Lauren Duhamel ,Luciano Santollani ,Elizabeth Fink ,Joseph R Palmeri ,Karl Dane Wittrup

Tumor-localized catalases can fail to alter tumor growth and transcriptional profiles in subcutaneous syngeneic mouse tumor models

肿瘤定位的过氧化氢酶无法改变皮下同基因小鼠肿瘤模型中的肿瘤生长和转录谱

Allison Sheen, Yash Agarwal, Keith M Cheah, Sarah C Cowles, Jordan A Stinson, Joseph R Palmeri, Hadley D Sikes, K Dane Wittrup

Collagen-Anchored Interleukin-2 and Interleukin-12 Safely Reprogram the Tumor Microenvironment in Canine Soft-Tissue Sarcomas

胶原锚定白细胞介素-2 和白细胞介素-12 安全地重新编程犬软组织肉瘤的肿瘤微环境

Jordan A Stinson #, Allison Sheen #, Noor Momin, Jordan Hampel, Rebecca Bernstein, Rebecca Kamerer, Bahaa Fadl-Alla, Jonathan Samuelson, Elizabeth Fink, Timothy M Fan #, K Dane Wittrup #

Overcoming lung cancer immunotherapy resistance by combining nontoxic variants of IL-12 and IL-2

通过联合使用无毒的IL-12和IL-2变体来克服肺癌免疫疗法耐药性

Brendan L Horton ,Alicia D D'Souza ,Maria Zagorulya ,Chloe V McCreery ,Gita C Abhiraman ,Lora Picton ,Allison Sheen ,Yash Agarwal ,Noor Momin ,K Dane Wittrup ,Forest M White ,K Christopher Garcia ,Stefani Spranger

Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer

消融放射治疗可提高生存率,但无法治愈前列腺癌和结直肠癌的本土小鼠模型

Daniel R Schmidt, Iva Monique T Gramatikov, Allison Sheen, Christopher L Williams, Martina Hurwitz, Laura E Dodge, Edward Holupka, W S Kiger 3rd, Milton R Cornwall-Brady, Wei Huang, Howard H Mak, Kathleen S Cormier, Charlene Condon, K Dane Wittrup, Ömer H Yilmaz, Mary Ann Stevenson, Julian D Down, S

Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity

肿瘤内注射明矾束缚细胞因子可引发强效且更安全的局部和全身抗癌免疫

Yash Agarwal, Lauren E Milling, Jason Y H Chang, Luciano Santollani, Allison Sheen, Emi A Lutz, Anthony Tabet, Jordan Stinson, Kaiyuan Ni, Kristen A Rodrigues, Tyson J Moyer, Mariane B Melo, Darrell J Irvine, K Dane Wittrup

An affinity threshold for maximum efficacy in anti-PD-1 immunotherapy

抗 PD-1 免疫疗法最大疗效的亲和力阈值

Sarah C Cowles, Allison Sheen, Luciano Santollani, Emi A Lutz, Brianna M Lax, Joseph R Palmeri, Gordon J Freeman, K Dane Wittrup

Intratumoral nanobody-IL-2 fusions that bind the tumor extracellular matrix suppress solid tumor growth in mice

肿瘤内注射的纳米抗体-IL-2融合物可与肿瘤细胞外基质结合,从而抑制小鼠实体瘤的生长。

Emi A Lutz ,Noor Jailkhani ,Noor Momin ,Ying Huang ,Allison Sheen ,Byong H Kang ,K Dane Wittrup ,Richard O Hynes

Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies

明矾锚定肿瘤内保留可提高 I 型干扰素疗法的耐受性和抗肿瘤功效

Emi A Lutz, Yash Agarwal, Noor Momin, Sarah C Cowles, Joseph R Palmeri, Ellen Duong, Vladlena Hornet, Allison Sheen, Brianna M Lax, Adrienne M Rothschilds, Darrell J Irvine, Stefani Spranger, K Dane Wittrup

Intrapartum Maternal Cardiac Arrest: A Simulation Case for Multidisciplinary Providers

产时母体心脏骤停:多学科医护人员模拟案例

Lee, Allison; Sheen, Jean-Ju; Richards, Stacey