日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Methyltransferases METTL7A and METTL7B Confer Resistance to Thiol-Based Histone Deacetylase Inhibitors

甲基转移酶 METTL7A 和 METTL7B 赋予对硫醇基组蛋白去乙酰化酶抑制剂的抗性

Robert W Robey #, Christina M Fitzsimmons #, Wilfried M Guiblet, William J E Frye, José M González Dalmasy, Li Wang, Drake A Russell, Lyn M Huff, Andrew J Perciaccante, Fatima Ali-Rahmani, Crystal C Lipsey, Heidi M Wade, Allison V Mitchell, Siddhardha S Maligireddy, David Terrero, Donna Butcher, Eli

A whole-genome CRISPR screen identifies the spindle accessory checkpoint as a locus of nab-paclitaxel resistance in a pancreatic cancer cell line

全基因组 CRISPR 筛选将纺锤体附属检查点确定为胰腺癌细胞系中白蛋白紫杉醇耐药位点

Priya Mondal #, George Alyateem #, Allison V Mitchell, Michael M Gottesman

A whole-genome CRISPR screen identifies the spindle accessory checkpoint as a locus of nab-paclitaxel resistance in pancreatic cancer cells

全基因组 CRISPR 筛选确定纺锤体附属检查点是胰腺癌细胞中白蛋白紫杉醇耐药位点

Priya Mondal, George Alyateem, Allison V Mitchell, Michael M Gottesman

FOXQ1 recruits the MLL complex to activate transcription of EMT and promote breast cancer metastasis

FOXQ1 募集 MLL 复合物激活 EMT 转录并促进乳腺癌转移

Allison V Mitchell, Ling Wu, C James Block, Mu Zhang, Justin Hackett, Douglas B Craig, Wei Chen, Yongzhong Zhao, Bin Zhang, Yongjun Dang, Xiaohong Zhang, Shengping Zhang, Chuangui Wang, Heather Gibson, Lori A Pile, Benjamin Kidder, Larry Matherly, Zhe Yang, Yali Dou, Guojun Wu

DDR2 coordinates EMT and metabolic reprogramming as a shared effector of FOXQ1 and SNAI1

DDR2 作为 FOXQ1 和 SNAI1 的共同效应子,协调 EMT 和代谢重编程

Allison V Mitchell, Jason Wu, Fanyan Meng, Lun Dong, C James Block, Won-Min Song, Bin Zhang, Jing Li, Guojun Wu

EGFL9 promotes breast cancer metastasis by inducing cMET activation and metabolic reprogramming

EGFL9 通过诱导 cMET 激活和代谢重编程促进乳腺癌转移

Fanyan Meng, Ling Wu, Lun Dong, Allison V Mitchell, C James Block, Jenney Liu, Haijun Zhang, Qing Lu, Won-Min Song, Bin Zhang, Wei Chen, Jiani Hu, Jian Wang, Qifeng Yang, Maik Hüttemann, Guojun Wu0

Disulfiram and BKM120 in Combination with Chemotherapy Impede Tumor Progression and Delay Tumor Recurrence in Tumor Initiating Cell-Rich TNBC

双硫仑和 BKM120 与化疗联合使用可阻止肿瘤进展并延迟肿瘤起始细胞丰富的 TNBC 的肿瘤复发

Ling Wu, Fanyan Meng, Lun Dong, C James Block, Allison V Mitchell, Jason Wu, Hyejeong Jang, Wei Chen, Lisa Polin, Qifeng Yang, Q Ping Dou, Guojun Wu