Transcriptional and epigenetic rewiring by the NUP98::KDM5A fusion oncoprotein directly activates CDK12.
NUP98::KDM5A 融合癌蛋白通过转录和表观遗传重编程直接激活 CDK12
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-59930-9
Troester Selina, Eder Thomas, Wukowits Nadja, Piontek Martin, Fernández-Pernas Pablo, Schmoellerl Johannes, Haladik Ben, Manhart Gabriele, Allram Melanie, Maurer-Granofszky Margarita, Scheidegger Nastassja, Nebral Karin, Superti-Furga Giulio, Meisel Roland, Bornhauser Beat, Valent Peter, Dworzak Michael N, Zuber Johannes, Boztug Kaan, Grebien Florian
