Serum-derived carcinoembryonic antigen (CEA) activates fibroblasts to induce a local re-modeling of the extracellular matrix that favors the engraftment of CEA-expressing tumor cells.

血清衍生的癌胚抗原 (CEA) 可激活成纤维细胞，诱导细胞外基质的局部重塑，从而有利于表达 CEA 的肿瘤细胞的植入