Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation
Defactinib 抑制 PYK2 对 IRF5 的磷酸化并减轻肠道炎症
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-021-27038-5
Grigory Ryzhakov #, Hannah Almuttaqi #, Alastair L Corbin, Dorothée L Berthold, Tariq Khoyratty, Hayley L Eames, Samuel Bullers, Claire Pearson, Zhichao Ai, Kristina Zec, Sarah Bonham, Roman Fischer, Luke Jostins-Dean, Simon P L Travis, Benedikt M Kessler, Irina A Udalova