日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Systemic HER3 ligand-mimicking nanobioparticles enter the brain and reduce intracranial tumour growth.

模拟 HER3 配体的全身性纳米生物颗粒进入大脑,减少颅内肿瘤的生长

Alonso-Valenteen Felix, Mikhael Simoun, Wang HongQiang, Sims Jessica, Taguiam Michael, Teh James, Sances Sam, Wong Michelle, Miao Tianxin, Srinivas Dustin, Gonzalez-Almeyda Nelyda, Cho Ryan H, Sanchez Romny, Nguyenle Kimngan, Serrano Erik, Ondatje Briana, Benhaghnazar Rebecca L, Gray Harry B, Gross Zeev, Yu John, Svendsen Clive N, Abrol Ravinder, Medina-Kauwe Lali K

Novel potent azetidine-based compounds irreversibly inhibit Stat3 activation and induce antitumor response against human breast tumor growth in vivo

新型强效氮杂环丁烷类化合物可不可逆地抑制Stat3活化,并在体内诱导抗肿瘤反应,抑制人乳腺肿瘤生长。

Yue, Peibin; Zhu, Yinsong; Brotherton-Pleiss, Christine; Fu, Wenzhen; Verma, Nagendra; Chen, Jasmine; Nakamura, Kayo; Chen, Weiliang; Chen, Yue; Alonso-Valenteen, Felix; Mikhael, Simoun; Medina-Kauwe, Lali; Kershaw, Kathleen M; Celeridad, Maria; Pan, Songqin; Limpert, Allison S; Sheffler, Douglas J; Cosford, Nicholas D P; Shiao, Stephen L; Tius, Marcus A; Lopez-Tapia, Francisco; Turkson, James

Discovery of Novel Azetidine Amides as Potent Small-Molecule STAT3 Inhibitors

发现新型氮杂环丁烷酰胺类化合物作为强效小分子STAT3抑制剂

Brotherton-Pleiss, Christine; Yue, Peibin; Zhu, Yinsong; Nakamura, Kayo; Chen, Weiliang; Fu, Wenzhen; Kubota, Casie; Chen, Jasmine; Alonso-Valenteen, Felix; Mikhael, Simoun; Medina-Kauwe, Lali; Tius, Marcus A; Lopez-Tapia, Francisco; Turkson, James

Syndecan-1 promotes lung fibrosis by regulating epithelial reprogramming through extracellular vesicles

Syndecan-1 通过调节细胞外囊泡介导的上皮细胞重编程促进肺纤维化

Parimon, Tanyalak; Yao, Changfu; Habiel, David M; Ge, Lingyin; Bora, Stephanie A; Brauer, Rena; Evans, Christopher M; Xie, Ting; Alonso-Valenteen, Felix; Medina-Kauwe, Lali K; Jiang, Dianhua; Noble, Paul W; Hogaboam, Cory M; Deng, Nan; Burgy, Olivier; Antes, Travis J; Königshoff, Melanie; Stripp, Barry R; Gharib, Sina A; Chen, Peter

A corrole nanobiologic elicits tissue-activated MRI contrast enhancement and tumor-targeted toxicity

一种corrole纳米生物制剂可引起组织激活的MRI对比增强和肿瘤靶向毒性

Sims, Jessica D; Hwang, Jae Youn; Wagner, Shawn; Alonso-Valenteen, Felix; Hanson, Chris; Taguiam, Jan Michael; Polo, Richard; Harutyunyan, Ira; Karapetyan, Gevorg; Sorasaenee, Karn; Ibrahim, Ahmed; Marban, Eduardo; Moats, Rex; Gray, Harry B; Gross, Zeev; Medina-Kauwe, Lali K

Photoexcitation of tumor-targeted corroles induces singlet oxygen-mediated augmentation of cytotoxicity

光激发肿瘤靶向咕啉可诱导单线态氧介导的细胞毒性增强

Hwang, Jae Youn; Lubow, David J; Chu, David; Sims, Jessica; Alonso-Valenteen, Felix; Gray, Harry B; Gross, Zeev; Farkas, Daniel L; Medina-Kauwe, Lali K