BRAF(V600E) patient derived colon cancer organoids identify biomarkers of response to EGFR and BRAF inhibition and replicate clinical data
BRAF(V600E)患者来源的结肠癌类器官可识别EGFR和BRAF抑制剂疗效的生物标志物，并能重现临床数据。
期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-026-03699-2
Kotarac, Anna; Osumi, Hiroki; Malt, Alexander; Alp, Keziban Merve; Jarosch, Armin; Werner, Johannes; Benary, Manuela; Neumann, Christopher C M; Yao, Ryoji; Mertins, Philipp; Eils, Roland; Beule, Dieter; Sers, Christine; Keilholz, Ulrich; Ishaque, Naveed; Stintzing, Sebastian; Vecchione, Loredana
肿瘤
肠癌
肿瘤免疫
EGF
BRAF
EGFR
3D/类器官
