Rituximab exerts its anti-arthritic effects via inhibiting NF-κB/GM-CSF/iNOS signaling in B cells in a mouse model of collagen-induced arthritis
利妥昔单抗通过抑制胶原诱导性关节炎小鼠模型中B细胞的NF-κB/GM-CSF/iNOS信号通路发挥其抗关节炎作用。
期刊:Heliyon
影响因子:3.6
doi:10.1016/j.heliyon.2023.e16673
Ansari, Mushtaq A; Nadeem, Ahmed; Attia, Sabry M; Bakheet, Saleh A; Alasmari, Abdullah F; Alomar, Hatun A; Al-Mazroua, Haneen A; Alhamed, Abdullah S; Shahid, Mudassar; Alqinyah, Mohammed; Assiri, Mohammed A; Al-Hamamah, Mohammed A; Alassmrry, Yasseen A; Ahmad, Sheikh F
M-CSF
B细胞
细胞生物学
iNOS
NF-κB
免疫/内分泌
GM-CSF
关节炎
信号转导
