文献库，生知库 | 链接生命科学的每一步

日期影响因子

Ambroxol mitigates cyclophosphamide-induced liver injury by suppressing TLR-4/NF-κB signaling and oxidative stress and upregulating cytoglobin, TXNRD1 and HMGB1

氨溴索通过抑制 TLR-4/NF-κB 信号通路和氧化应激，并上调细胞球蛋白、TXNRD1 和 HMGB1，从而减轻环磷酰胺引起的肝损伤。

期刊:World Journal of Gastroenterology

影响因子:5.4

doi:10.3748/wjg.v31.i35.108139

Alruhaimi, Reem S; Hassanein, Emad H M; Alnasser, Sulaiman M; Ahmeda, Ahmad F; Althagafy, Hanan S; Abd El-Ghafar, Omnia A M; Mahmoud, Ayman M

细胞生物学

发表日期：2025

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Candesartan preserves aortic structure and function in cisplatin-treated rats by upregulating SIRT1/Nrf2/HO-1 signaling and suppressing oxidative stress, TLR-4/NF-κB signaling, and necroptosis

坎地沙坦通过上调SIRT1/Nrf2/HO-1信号通路并抑制氧化应激、TLR-4/NF-κB信号通路和坏死性凋亡，在顺铂治疗的大鼠中维持主动脉的结构和功能。

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2025.1678921

Mahmoud, Ayman M; Alnasser, Sulaiman M; Abd El-Ghafar, Omnia A M; Alruhaimi, Reem S; Althagafy, Hanan S; Atwa, Ahmed M; Hassanein, Emad H M

发表日期：2025

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Computationally Guided Structural Modification of Centaureidin: A Novel Approach for Enhancing Antioxidant and Antitumor Activities for Drug Development

计算机引导的半胱氨酸结构修饰：一种增强抗氧化和抗肿瘤活性的新药物研发方法

doi:10.1111/cbdd.70149

Alruhaimi, Reem S; Kamel, Emadeldin M; Alnasser, Sulaiman M; Elbagory, Ibrahim; Mahmoud, Ayman M; Lamsabhi, Al Mokhtar

发表日期：2025

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Mechanistic insights into carbonic anhydrase IX inhibition by coumarins from Calendula officinalis: in vitro and in silico approaches

金盏花香豆素抑制碳酸酐酶IX的机制研究：体外和计算机模拟方法

期刊:RSC Advances

影响因子:4.6

doi:10.1039/d4ra05984k

Alruhaimi, Reem S; Kamel, Emadeldin M; Alnasser, Sulaiman M; Alzoghaibi, Mohammed A; Lamsabhi, Al Mokhtar; Mahmoud, Ayman M

发表日期：2024

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Integrating Computational Modeling and Experimental Validation to Unveil Tyrosinase Inhibition Mechanisms of Flavonoids from Alhagi graecorum

结合计算建模和实验验证，揭示希腊海参中黄酮类化合物的酪氨酸酶抑制机制

期刊:ACS Omega

影响因子:4.3

doi:10.1021/acsomega.4c07624

Alruhaimi, Reem S; Mahmoud, Ayman M; Alnasser, Sulaiman M; Alotaibi, Mohammed F; Elbagory, Ibrahim; El-Bassuony, Ashraf A; Lamsabhi, Al Mokhtar; Kamel, Emadeldin M

发表日期：2024

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A flavonoid-rich fraction of Euphorbia peplus attenuates hyperglycemia, insulin resistance, and oxidative stress in a type 2 diabetes rat model.

富含黄酮类化合物的Euphorbia peplus成分可减轻2型糖尿病大鼠模型中的高血糖、胰岛素抵抗和氧化应激

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2023.1204641

Alruhaimi Reem S, Mostafa-Hedeab Gomaa, Abduh Maisa Siddiq, Bin-Ammar Albandari, Hassanein Emad H M, Kamel Emadeldin M, Mahmoud Ayman M

发表日期：2023

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Multitargeted molecular modelling of alginic acid modified with 4-aminophenol dopped with silver nanoparticles as a potent cytotoxic agent

利用多靶点分子建模方法研究了经4-氨基苯酚修饰并掺杂银纳米粒子的藻酸作为一种强效细胞毒性剂的作用。

影响因子:3.6

doi:10.1016/j.heliyon.2023.e17106

Mahmoud, Haneen A; Kamel, Emadeldin M; Mahmoud, Ayman M; Alruhaimi, Reem S; El-Zanaty, Ali M; Abd El-Salam, Hanafy M; Abdel-Gawad, Omayma F

细胞生物学

发表日期：2023

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Multi-target action of Garcinia livingstonei extract and secondary metabolites against fatty acid synthase, α-glucosidase, and xanthine oxidase

藤黄果提取物及其次生代谢产物对脂肪酸合成酶、α-葡萄糖苷酶和黄嘌呤氧化酶的多靶点作用

期刊:Saudi Pharmaceutical Journal

影响因子:3.4

doi:10.1016/j.jsps.2023.101762

Abdul-Rahman, Azza M; Elwekeel, Ahlam; Alruhaimi, Reem S; Kamel, Emadeldin M; Bin-Ammar, Albandari; Mahmoud, Ayman M; Moawad, Abeer S; Zaki, Mohamed A

发表日期：2023

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An integrated phytochemical, in silico and in vivo approach to identify the protective effect of Caroxylon salicornicum against cisplatin hepatotoxicity

采用植物化学、计算机模拟和体内实验相结合的方法，鉴定盐角草对顺铂肝毒性的保护作用

期刊:Saudi Pharmaceutical Journal

影响因子:3.4

doi:10.1016/j.jsps.2023.101766

Ramadan, Shaymaa A; Kamel, Emadeldin M; Alruhaimi, Reem S; Bin-Ammar, Albandari; Ewais, Madeha A; Khowailed, Akef A; Hassanein, Emad H M; Mahmoud, Ayman M

发表日期：2023

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The Effect of Dietary Saccharomyces cerevisiae on Growth Performance, Oxidative Status, and Immune Response of Sea Bream (Sparus aurata)

日粮中添加酿酒酵母对金头鲷（Sparus aurata）生长性能、氧化状态和免疫反应的影响

期刊:Life-Basel

影响因子:3.4

doi:10.3390/life12071013

El-Bab, Ahmed F Fath; Saghir, Sultan A M; El-Naser, Ibrahim Atta Abu; El-Kheir, Salwa M M Abo; Abdel-Kader, Marwa F; Alruhaimi, Reem S; Alqhtani, Haifa A; Mahmoud, Ayman M; Naiel, Mohammed A E; El-Raghi, Ali Ali

免疫/内分泌

发表日期：2022

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