日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Translational lipidomics reveals BMP and its precursor LPG as biomarkers for CLN5 Batten disease

转化脂质组学揭示BMP及其前体LPG可作为CLN5巴顿病的生物标志物。

Rawat, Eshaan S; Manfred, Nick; Alsohybe, Hisham N; Dong, Wentao; Peña, Isabelle V; Idris, Maryam; Posern, Christian; Westermann, Lena M; Murray, Samantha J; Panneman, Daan M; Vecchia, Stefania Della; Doccini, Stefano; Marchese, Maria; Santorelli, Filippo M; van Hasselt, Peter M; Mitchell, Nadia L; Schulz, Angela; Abu-Remaileh, Monther

PLA2G15 is a BMP hydrolase and its targeting ameliorates lysosomal disease.

PLA2G15 是一种 BMP 水解酶,靶向 PLA2G15 可改善溶酶体疾病

Nyame Kwamina, Xiong Jian, Alsohybe Hisham N, de Jong Arthur P H, Peña Isabelle V, de Miguel Ricardo, Brummelkamp Thijn R, Hartmann Guido, Nijman Sebastian M B, Raaben Matthijs, Simcox Judith A, Blomen Vincent A, Abu-Remaileh Monther

PLA2G15 is a Lysosomal BMP Hydrolase and its Targeting Ameliorates Lysosomal Disease

PLA2G15 是一种溶酶体 BMP 水解酶,靶向 PLA2G15 可改善溶酶体疾病。

Nyame, Kwamina; Xiong, Jian; Alsohybe, Hisham N; de Jong, Arthur Ph; Peña, Isabelle V; de Miguel, Ricardo; Brummelkamp, Thijn R; Hartmann, Guido; Nijman, Sebastian M B; Raaben, Matthijs; Simcox, Judith A; Blomen, Vincent A; Abu-Remaileh, Monther