文献库，生知库 | 链接生命科学的每一步

日期影响因子

Transitive prediction of small-molecule function through alignment of high-content screening resources

通过高内涵筛选资源的比对，对小分子功能进行传递性预测

期刊:Nature Biotechnology

影响因子:41.7

doi:10.1038/s41587-025-02729-2

Bao, Feng; Li, Li; Hammerlindl, Heinz; Shen, Susan Q; Hammerlindl, Sabrina; Altschuler, Steven J; Wu, Lani F

发表日期：2025

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A phenopushing platform to identify compounds that alleviate acute hypoxic stress by fast-tracking cellular adaptation.

表型推进平台，用于识别能够通过加速细胞适应来缓解急性缺氧应激的化合物

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-57754-1

Li Li, Hammerlindl Heinz, Shen Susan Q, Bao Feng, Hammerlindl Sabrina, Altschuler Steven J, Wu Lani F

细胞生物学

发表日期：2025

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Targeting PRMT1 Reduces Cancer Persistence and Tumor Relapse in EGFR- and KRAS-Mutant Lung Cancer

靶向PRMT1可降低EGFR和KRAS突变型肺癌的癌症持续存在和肿瘤复发率

期刊:Cancer Research Communications

影响因子:3.3

doi:10.1158/2767-9764.CRC-24-0389

Sun, Xiaoxiao; Kumbier, Karl; Gayathri, Savitha; Steri, Veronica; Wu, Lani F; Altschuler, Steven J

发表日期：2025

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Targeting therapy-persistent residual disease

靶向治疗——持续性残留病

期刊:Nature Cancer

影响因子:28.5

doi:10.1038/s43018-024-00819-9

Sun, Xiaoxiao; Wu, Lani F; Altschuler, Steven J; Hata, Aaron N

发表日期：2024

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Searching for molecular hypoxia sensors among oxygen-dependent enzymes

在氧依赖性酶中寻找分子缺氧传感器

影响因子:6.4

doi:10.7554/eLife.87705

Li, Li; Shen, Susan; Bickler, Philip; Jacobson, Matthew P; Wu, Lani F; Altschuler, Steven J

发表日期：2023

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Selection of Optimal Cell Lines for High-Content Phenotypic Screening

筛选用于高内涵表型筛选的最佳细胞系

期刊:ACS Chemical Biology

影响因子:3.8

doi:10.1021/acschembio.2c00878

Heinrich, Louise; Kumbier, Karl; Li, Li; Altschuler, Steven J; Wu, Lani F

细胞生物学

发表日期：2023

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Small Molecule in situ Resin Capture - A Compound First Approach to Natural Product Discovery

小分子原位树脂捕获——一种化合物优先的天然产物发现方法

doi:10.1101/2023.03.02.530684

Bogdanov, Alexander; Salib, Mariam N; Chase, Alexander B; Hammerlindl, Heinz; Muskat, Mitchell N; Luedtke, Stephanie; Barbosa da Silva, Elany; O'Donoghue, Anthony J; Wu, Lani F; Altschuler, Steven J; Molinski, Tadeusz F; Jensen, Paul R

发表日期：2023

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Modeling Cell-to-Cell Communication Networks Using Response-Time Distributions

利用响应时间分布对细胞间通信网络进行建模

期刊:Cell Systems

影响因子:7.7

doi:10.1016/j.cels.2018.01.016

Thurley, Kevin; Wu, Lani F; Altschuler, Steven J

细胞生物学

发表日期：2018

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Telomerase-Mediated Strategy for Overcoming Non-Small Cell Lung Cancer Targeted Therapy and Chemotherapy Resistance.

端粒酶介导策略克服非小细胞肺癌靶向治疗和化疗耐药性

期刊:Neoplasia

影响因子:7.7

doi:10.1016/j.neo.2018.06.002

Mender Ilgen, LaRanger Ryan, Luitel Krishna, Peyton Michael, Girard Luc, Lai Tsung-Po, Batten Kimberly, Cornelius Crystal, Dalvi Maithili P, Ramirez Michael, Du Wenting, Wu Lani F, Altschuler Steven J, Brekken Rolf, Martinez Elisabeth D, Minna John D, Wright Woodring E, Shay Jerry W

细胞生物学

发表日期：2018

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Combination Therapy Targeting BCL6 and Phospho-STAT3 Defeats Intratumor Heterogeneity in a Subset of Non-Small Cell Lung Cancers

针对BCL6和磷酸化STAT3的联合疗法可克服部分非小细胞肺癌的肿瘤内异质性

期刊:Cancer Research

影响因子:16.6

doi:10.1158/0008-5472.CAN-15-3052

Deb, Dhruba; Rajaram, Satwik; Larsen, Jill E; Dospoy, Patrick D; Marullo, Rossella; Li, Long Shan; Avila, Kimberley; Xue, Fengtian; Cerchietti, Leandro; Minna, John D; Altschuler, Steven J; Wu, Lani F

细胞生物学

发表日期：2017

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