日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Conformational Dynamics and Catalytic Backups in a Hyper-thermostable Engineered Archaeal Protein Tyrosine Phosphatase

超耐热工程化古菌蛋白酪氨酸磷酸酶的构象动力学和催化备份

Yehorova, Dariia; Alansson, Nikolas; Shen, Ruidan; Denson, Joshua M; Robinson, Michael; Risso, Valeria A; Ramirez Molina, Nuria; Loria, J Patrick; Gaucher, Eric A; Sanchez-Ruiz, Jose M; Hengge, Alvan C; Johnson, Sean J; Kamerlin, Shina C L

Redefining the Limits of Functional Continuity in the Early Evolution of P-Loop NTPases

重新定义P环NTP酶早期进化中功能连续性的界限

Demkiv, Andrey O; Toledo-Patiño, Saacnicteh; Medina-Carmona, Encarnación; Berg, Andrej; Pinto, Gaspar P; Parracino, Antonietta; Sanchez-Ruiz, Jose M; Hengge, Alvan C; Laurino, Paola; Longo, Liam M; Kamerlin, Shina Caroline Lynn

Conformational Dynamics and Catalytic Backups in a Hyper-Thermostable Engineered Archaeal Protein Tyrosine Phosphatase

超耐热工程化古菌蛋白酪氨酸磷酸酶的构象动力学和催化备份

Yehorova, Dariia; Alansson, Nikolas; Shen, Ruidan; Denson, Joshua M; Robinson, Michael; Risso, Valeria A; Molina, Nuria Ramirez; Loria, J Patrick; Gaucher, Eric A; Sanchez-Ruiz, Jose M; Hengge, Alvan C; Johnson, Sean J; Kamerlin, Shina C L

SHP-1 Variants Broaden the Understanding of pH-Dependent Activities in Protein Tyrosine Phosphatases

SHP-1 变体拓宽了对蛋白酪氨酸磷酸酶中 pH 依赖性活性的理解

Ruidan Shen, Alfie-Louise R Brownless, Nikolas Alansson, Marina Corbella, Shina C L Kamerlin, Alvan C Hengge

Sequence - dynamics - function relationships in protein tyrosine phosphatases

蛋白质酪氨酸磷酸酶的序列-动力学-功能关系

Crean, Rory M; Corbella, Marina; Calixto, Ana R; Hengge, Alvan C; Kamerlin, Shina C L

Insights into the importance of WPD-loop sequence for activity and structure in protein tyrosine phosphatases

深入探究WPD环序列对蛋白质酪氨酸磷酸酶活性和结构的重要性

Shen, Ruidan; Crean, Rory M; Olsen, Keith J; Corbella, Marina; Calixto, Ana R; Richan, Teisha; Brandão, Tiago A S; Berry, Ryan D; Tolman, Alex; Loria, J Patrick; Johnson, Sean J; Kamerlin, Shina C L; Hengge, Alvan C

Plasmodium falciparum finds the winning combination

恶性疟原虫找到了制胜组合

Hengge, Alvan C

Significant Loop Motions in the SsoPTP Protein Tyrosine Phosphatase Allow for Dual General Acid Functionality

SsoPTP 蛋白酪氨酸磷酸酶中的显著环路运动允许双重通用酸功能

Justin Pinkston, Jihye Jo, Keith J Olsen, Drake Comer, Charsti A Glaittli, J Patrick Loria, Sean J Johnson, Alvan C Hengge

Modeling the Alkaline Hydrolysis of Diaryl Sulfate Diesters: A Mechanistic Study

二芳基硫酸酯二酯碱性水解的建模:机理研究

Szeler, Klaudia; Williams, Nicholas H; Hengge, Alvan C; Kamerlin, Shina C L

Conservative tryptophan mutants of the protein tyrosine phosphatase YopH exhibit impaired WPD-loop function and crystallize with divanadate esters in their active sites

蛋白酪氨酸磷酸酶 YopH 的保守色氨酸突变体表现出 WPD 环功能受损,并在其活性位点与二钒酸酯共结晶。

Moise, Gwendolyn; Gallup, Nathan M; Alexandrova, Anastassia N; Hengge, Alvan C; Johnson, Sean J