日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Spatial single-cell multiomics reveals peripheral immune dysfunction in Parkinson's and inflammatory bowel disease

空间单细胞多组学揭示帕金森病和炎症性肠病中的外周免疫功能障碍

Bolen, MacKenzie L; Buendia, Marc; Shi, Ji; Staley, Hannah; Kachergus, Jennifer M; Efron, Philip A; Park, Gwoncheol; Nagpal, Ravinder; Alvarez, Stephan D; Xue, Qing-Shan; McFarland, Nikolaus R; Zimmermann, Ellen M; Forsmark, Christopher E; Menees, Kelly B; Salas, Azucena; Aubrey Thompson, E; Tansey, Malú Gámez

Comparative analysis of Parkinson's and inflammatory bowel disease gut microbiomes reveals shared butyrate-producing bacteria depletion

帕金森病和炎症性肠病肠道微生物组的比较分析揭示了丁酸产生菌的共同减少

Krueger, Maeve E; Boles, Jake Sondag; Simon, Zachary D; Alvarez, Stephan D; McFarland, Nikolaus R; Okun, Michael S; Zimmermann, Ellen M; Forsmark, Christopher E; Tansey, Malú Gámez

Peripheral immune cell response to stimulation stratifies Parkinson's disease progression from prodromal to clinical stages.

外周免疫细胞对刺激的反应可将帕金森病的进展从前驱期到临床期进行分层

Mark Julian R, Titus Ann M, Staley Hannah A, Alvarez Stephan, Mahn Savanna, McFarland Nikolaus R, Wallings Rebecca L, Tansey Malú Gámez

Single-cell multiomics identifies both shared and unique features of immune dysfunction in Parkinson's disease and inflammatory bowel disease colon, plasma and stool

单细胞多组学分析揭示了帕金森病和炎症性肠病结肠、血浆和粪便中免疫功能障碍的共同特征和独特特征

Bolen, MacKenzie L; Buendia, Marc; Shi, Ji; Staley, Hannah; Kachergus, Jennifer M; Efron, Philip A; Park, Gwoncheol; Nagpal, Ravinder; Alvarez, Stephan D; Xue, Qing-Shan; McFarland, Nikolaus R; Zimmermann, Ellen M; Forsmark, Christopher E; Menees, Kelly B; Salas, Azucena; Thompson, E Aubrey; Tansey, Malú Gámez

Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with the retinoblastoma protein family

LxCxE 依赖性蛋白质与视网膜母细胞瘤蛋白家族相互作用的可调亲和力和特异性的结构基础

Sivasankar Putta, Lucia Alvarez, Stephan Lüdtke, Peter Sehr, Gerd A Müller, Samantha M Fernandez, Sarvind Tripathi, Joe Lewis, Toby J Gibson, Lucia B Chemes, Seth M Rubin

A phase II evaluation of temsirolimus with carboplatin and paclitaxel followed by temsirolimus consolidation in clear cell ovarian cancer: An NRG oncology trial

一项针对透明细胞卵巢癌的 II 期临床试验,评估了替西罗莫司联合卡铂和紫杉醇方案化疗后序贯替西罗莫司巩固治疗的疗效:NRG 肿瘤学试验

Farley, John H; Brady, William E; O'Malley, David; Fujiwara, Keiichi; Yonemori, Kan; Bonebrake, Albert; Secord, Angeles Alvarez; Stephan, Jean-Marie; Walker, Joan L; Nam, Joo-Hyun; Birrer, Michael J; Gershenson, David M