日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Umbilical Cord Blood Reduced Relapse but Increased Nonrelapse Mortality Compared to Matched Unrelated Donor Transplantation in Pediatric Acute Myeloid Leukemia With Active Disease: A CIBMTR 2008 to 2017 Analysis of Donor Source and Residual Disease

在活动期儿童急性髓系白血病中，与匹配无关供者移植相比，脐带血移植降低了复发率，但增加了非复发死亡率：一项基于2008年至2017年CIBMTR数据，分析了供者来源和残留疾病情况。

期刊:Transplantation and Cellular Therapy
影响因子:4.4
doi:10.1016/j.jtct.2025.01.889
Takahashi, Takuto; Wachter, Franziska; Alvarez Calderon, Francesca; Kapadia, Malika; Qayed, Muna; Keating, Amy K
白血病
发表日期：2025
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PTPN2-KO CAR-T Cells Demonstrate Enhanced Effector Function, CNS Infiltration, and Toxicity in a Non-Human Primate CAR-T Model

在非人灵长类动物CAR-T模型中，PTPN2-KO CAR-T细胞表现出增强的效应功能、中枢神经系统浸润和毒性。

期刊:
影响因子:
doi:10.1101/2025.09.17.676426
Alvarez Calderon, Francesca; Fleming, Ryan A; Winschel, Marlana; Gorfinkel, Lev; Sutherland, Rebecca; Michaelis, Katherine; Kaminski, James; Palato, Elisa Rojas; Ingersoll, Kayleigh; Cagnin, Lorenzo; Lane, Jennifer; Tkachev, Victor; Kean, Leslie S; Gerdemann, Ulrike
Primate
毒理研究
Human
免疫/内分泌
细胞生物学
T细胞
神经科学
T细胞
发表日期：2025
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Precision Editing of Cyclophilin A Generates Cyclosporine and Voclosporin Resistant Cellular Therapies

对环孢素A进行精准编辑可产生对环孢素和沃克洛孢素耐药的细胞疗法

期刊:
影响因子:
doi:10.1101/2025.04.30.651441
Wobma, Holly; Alvarez Calderon, Francesca; Dong, Jiayi; Omdahl, Kayleigh; Rui, Xianliang; Rojas Palato, Elisa J; Bermea, Rene S; Albanese, Alexandre; Wachter, Franziska; Winschel, Marlana; Michaelis, Katherine A; Cagnin, Lorenzo; Tkachev, Victor; Prockop, Susan E; Nigrovic, Peter A; Blazar, Bruce R; Gerdemann, Ulrike; Kean, Leslie S
细胞生物学
发表日期：2025
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Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate-conditioned Fanconi anemia mice

在经 CD45 抗体药物偶联物预处理的范可尼贫血小鼠中，同种异体移植未出现明显毒性或移植物抗宿主病 (GVHD)。

期刊:Blood
影响因子:23.1
doi:10.1182/blood.2023023549
Saha, Asim; Palchaudhuri, Rahul; Lanieri, Leanne; Hyzy, Sharon; Riddle, Megan J; Panthera, Jamie; Eide, Cindy R; Tolar, Jakub; Panoskaltsis-Mortari, Angela; Gorfinkel, Lev; Tkachev, Victor; Gerdemann, Ulrike; Alvarez-Calderon, Francesca; Palato, Elisa Rojas; MacMillan, Margaret L; Wagner, John E; Kean, Leslie S; Osborn, Mark J; Kiem, Hans-Peter; Scadden, David T; Olson, Lisa M; Blazar, Bruce R
T细胞
代谢
CD45
毒理研究
贫血
CD4
发表日期：2024
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B-cell-directed CAR T-cell therapy activates CD8+ cytotoxic CARneg bystander T cells in patients and nonhuman primates

B细胞靶向CAR-T细胞疗法可激活患者和非人灵长类动物体内的CD8+细胞毒性CAR-Neg旁观者T细胞。

期刊:Blood
影响因子:23.1
doi:10.1182/blood.2023022717
Kaminski, James; Fleming, Ryan A; Alvarez-Calderon, Francesca; Winschel, Marlana B; McGuckin, Connor; Ho, Emily E; Eng, Fay; Rui, Xianliang; Keskula, Paula; Cagnin, Lorenzo; Charles, Joanne; Zavistaski, Jillian; Margossian, Steven P; Kapadia, Malika A; Rottman, James B; Lane, Jennifer; Baumeister, Susanne H C; Tkachev, Victor; Shalek, Alex K; Kean, Leslie S; Gerdemann, Ulrike
B细胞
T细胞
CD8
T细胞
细胞生物学
毒理研究
免疫/内分泌
发表日期：2024
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Targeting of the CD161 inhibitory receptor enhances T-cell-mediated immunity against hematological malignancies

靶向 CD161 抑制性受体可增强 T 细胞介导的抗血液系统恶性肿瘤免疫力。

期刊:Blood
影响因子:23.1
doi:10.1182/blood.2023022882
Alvarez Calderon, Francesca; Kang, Byong H; Kyrysyuk, Oleksandr; Zheng, Shiwei; Wang, Hao; Mathewson, Nathan D; Luoma, Adrienne M; Ning, Xiaohan; Pyrdol, Jason; Cao, Xuan; Suvà, Mario L; Yuan, Guo-Cheng; Wittrup, K Dane; Wucherpfennig, Kai W
CD16
肿瘤
CD161
T细胞
肿瘤免疫
信号转导
细胞生物学
免疫/内分泌
发表日期：2024
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Human OX40L-CAR-T(regs) target activated antigen-presenting cells and control T cell alloreactivity.

人类 OX40L-CAR-T(regs) 靶向活化的抗原呈递细胞并控制 T 细胞同种异体反应性

期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.adj9331
Rui Xianliang, Alvarez Calderon Francesca, Wobma Holly, Gerdemann Ulrike, Albanese Alexandre, Cagnin Lorenzo, McGuckin Connor, Michaelis Katherine A, Naqvi Kisa, Blazar Bruce R, Tkachev Victor, Kean Leslie S
细胞生物学
Human
发表日期：2024
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Bioluminescence imaging of leukemia cell lines in vitro and in mouse xenografts: effects of monoclonal and polyclonal cell populations on intensity and kinetics of photon emission

体外和鼠异种移植模型中白血病细胞系的生物发光成像：单克隆和多克隆细胞群对光子发射强度和动力学的影响

期刊:Journal of Hematology & Oncology
影响因子:40.4
doi:10.1186/1756-8722-6-10
Christoph, Sandra; Schlegel, Jennifer; Alvarez-Calderon, Francesca; Kim, Yong-Mi; Brandao, Luis N; DeRyckere, Deborah; Graham, Douglas K
白血病
细胞生物学
发表日期：2013
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Using functional genomics to overcome therapeutic resistance in hematological malignancies

利用功能基因组学克服血液恶性肿瘤的治疗耐药性

期刊:Immunologic Research
影响因子:3.1
doi:10.1007/s12026-012-8353-z
Alvarez-Calderon, Francesca; Gregory, Mark A; DeGregori, James
肿瘤
肿瘤免疫
治疗耐药
发表日期：2013
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Wnt/Ca2+/NFAT signaling maintains survival of Ph+ leukemia cells upon inhibition of Bcr-Abl

Wnt/Ca2+/NFAT信号通路在Bcr-Abl抑制后维持Ph+白血病细胞的存活。

期刊:Cancer Cell
影响因子:44.5
doi:10.1016/j.ccr.2010.04.025
Gregory, Mark A; Phang, Tzu L; Neviani, Paolo; Alvarez-Calderon, Francesca; Eide, Christopher A; O'Hare, Thomas; Zaberezhnyy, Vadym; Williams, Richard T; Druker, Brian J; Perrotti, Danilo; Degregori, James
白血病
信号转导
细胞生物学
Wnt/β-Catenin
发表日期：2010
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