日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rate-of-Kill (RoK) assays to triage large compound sets for Chagas disease drug discovery: Application to GSK Chagas Box

利用杀伤率 (RoK) 检测方法筛选用于恰加斯病药物研发的大量化合物:以葛兰素史克恰加斯病盒为例

Cantizani, Juan; Gamallo, Pablo; Cotillo, Ignacio; Alvarez-Velilla, Raquel; Martin, Julio

Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discovery

锥虫拓扑异构酶再探:新的结构发现及其在药物研发中的作用

Balaña-Fouce, Rafael; Alvarez-Velilla, Raquel; Fernández-Prada, Christopher; García-Estrada, Carlos; Reguera, Rosa M

Synthesis of marine α-methoxylated fatty acid analogs that effectively inhibit the topoisomerase IB from Leishmania donovani with a mechanism different from that of camptothecin

合成海洋α-甲氧基化脂肪酸类似物,以不同于喜树碱的机制有效抑制杜氏利什曼原虫的拓扑异构酶IB

Néstor M Carballeira, Nashbly Montano, Raquel Alvarez-Velilla, Christopher F Prada, Rosa M Reguera, Rafael Balaña-Fouce

Appraisal of a Leishmania major strain stably expressing mCherry fluorescent protein for both in vitro and in vivo studies of potential drugs and vaccine against cutaneous leishmaniasis

评估稳定表达 mCherry 荧光蛋白的利什曼原虫菌株,以用于针对皮肤利什曼病的潜在药物和疫苗的体外和体内研究

Estefania Calvo-Álvarez, Nestor Adrian Guerrero, Raquel Alvarez-Velilla, Christopher Fernández Prada, Jose María Requena, Carmen Punzón, Miguel Ángel Llamas, Francisco J Arévalo, Luis Rivas, Manuel Fresno, Yolanda Pérez-Pertejo, Rafael Balaña-Fouce, Rosa M Reguera