AAV-mediated neuronal expression of an scFv antibody selective for Aβ oligomers protects synapses and rescues memory in Alzheimer models
在阿尔茨海默病模型中，AAV介导的神经元表达选择性针对Aβ寡聚体的scFv抗体可保护突触并挽救记忆。
期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2022.11.002
Selles, Maria Clara; Fortuna, Juliana T S; Cercato, Magali C; Santos, Luis Eduardo; Domett, Luciana; Bitencourt, Andre L B; Carraro, Mariane Favero; Souza, Amanda S; Janickova, Helena; Azevedo, Caroline Vieira; Campos, Henrique Correia; de Souza, Jorge M; Alves-Leon, Soniza; Prado, Vania F; Prado, Marco A M; Epstein, Alberto L; Salvetti, Anna; Longo, Beatriz Monteiro; Arancio, Ottavio; Klein, William L; Sebollela, Adriano; De Felice, Fernanda G; Jerusalinsky, Diana A; Ferreira, Sergio T
