日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Examination of Coligands in Mefloquine-Metal Complexes Reveals the Structural Determinants of Activity against Plasmodium falciparum and Schistosoma mansoni

对甲氟喹-金属配合物中配体的研究揭示了其抗恶性疟原虫和曼氏血吸虫活性的结构决定因素

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c03739
Villarreal, Wilmer; Quadros, Helenita Costa; Colina-Vegas, Legna; Aboagye, Sammy Y; Dziwornu, Godwin Akpeko; Ribeiro, Gabriel H; Barros, Ariane Isis; Kucharski, Dawid Jakub; Rahbari, Mahsa; Brandstädter, Christina; D'Alessandro, Sarah; Basilico, Nicoletta; Masike, Keabetswe; Mehlala, Nandi; Nobrega, Joaquim Araújo; Deflon, Victor M; Navarro, Maribel; Boratyński, Przemysław J; Chibale, Kelly; Williams, David L; Batista, Alzir A; Moreira, Diogo R M
发表日期：2026
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Para-substituted benzoic acid ruthenium(ii) complexes: structural features modulating cytotoxicity

对位取代苯甲酸钌(II)配合物：调节细胞毒性的结构特征

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d5ra07271a
Dutra, Jocely L; Marcon, Pedro H S; Moselli, Gustavo; Niquini, Fabiano M; da Costa, João Victor F; Moraes, Carlos André F; Braga, Ataualpa A C; Ellena, Javier; Batista, Alzir A; de Araujo-Neto, João Honorato
毒理研究
细胞生物学
发表日期：2026
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Synthesis and Structure Elucidation of New NSAID Diphosphine Ruthenium(II) Complexes as Potential Anticancer Agents: DNA/BSA Binding and Cytotoxicity Assays

新型非甾体抗炎药二膦钌(II)配合物的合成与结构解析及其作为潜在抗癌药物的应用：DNA/BSA结合和细胞毒性试验

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.5c12981
Carvalho, Diogo E L; Teixeira, Tamara; de Araujo-Neto, João Honorato; Batista, Alzir A; Fragoso, Keven S; Oliveira, Katia M; Corrêa, Rodrigo S
细胞生物学
肿瘤
肿瘤免疫
毒理研究
发表日期：2026
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Copper(II)-5-chloro-2-hydroxybenzophenone Complexes with N-N Donors: Structural Insights and Antitumor Activity against A2780 Human Ovarian Cancer Cells of a Bathophen Derivative

铜(II)-5-氯-2-羟基二苯甲酮与NN供体配合物：结构解析及对A2780人卵巢癌细胞的抗肿瘤活性研究（一种巴托芬衍生物）

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.5c11889
B de Carvalho, Alexandre; Palmeira-Mello, Marcos V; de Souza, Paulo N; Mendes Abe, Saulo H; Balena G Filho, José; Andrade, Marcelo B; Corrêa, Rodrigo S; Batista, Alzir A; Ellena, Javier
肿瘤
肿瘤免疫
卵巢癌
Human
细胞生物学
发表日期：2026
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Enhanced Anticancer Potential of Pd(II)-Thiosemicarbazone Complexes: Selectivity, Mechanisms, and 3D Models

Pd(II)-硫代氨基脲配合物增强的抗癌潜力：选择性、机制和三维模型

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics17070829
Lima, Mauro A; Teixeira, Tamara; Fortaleza, Dario B; Pereira, George B S; Akinyemi, Amos O; Moraes, Carlos André Ferreira; Forim, Moacir R; Batista, Alzir A; Dutra, Jocely L; Araujo-Neto, João H; Ellena, Javier A; Rocha, Fillipe V
肿瘤
肿瘤免疫
发表日期：2025
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Ru(II)-Fenamic-Based Complexes as Promising Human Ovarian Antitumor Agents: DNA Interaction, Cellular Uptake, and Three-Dimensional Spheroid Models.

Ru(II)-芬那酸基配合物作为有前景的人类卵巢抗肿瘤药物：DNA相互作用、细胞摄取和三维球体模型

期刊:Inorganic Chemistry
影响因子:4.7
doi:10.1021/acs.inorgchem.4c04344
Teixeira Tamara, Palmeira-Mello Marcos V, Machado Pedro Henrique, Moraes Carlos A F, Pinto Camila, Costa Rayane C, Badaró Wladimir, Gomes Neto José A, Ellena Javier, Vieira Rocha Fillipe, Batista Alzir A, Correa Rodrigo S
细胞生物学
肿瘤
Human
肿瘤免疫
发表日期：2025
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Palladium(II)-Complexed meso-Tetra(4-pyridyl)porphyrin: Photodynamic Efficacy in 3D Pancreatic Cancer Models.

钯(II)络合的内消旋-四(4-吡啶基)卟啉：在3D胰腺癌模型中的光动力疗效。

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.5c09619
Cruz de Moraes Edynara, do Carmo Silva Lívia, Santana de Curcio Juliana, Graça Alex Marchezini, Batista Alzir Azevedo, Silveira Lacerda Elisângela de Paula, Gonçalves Pablo José
胰腺癌
肿瘤
发表日期：2025
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Atypical diabetic foot ulcer turning into squamous cell carcinoma

非典型糖尿病足溃疡转化为鳞状细胞癌

期刊:Journal of Surgical Case Reports
影响因子:0.5
doi:10.1093/jscr/rjaf818
Alzir, Magdi S; Badahdah, Hani Mohammed; Alqawlaq, Abdulelah K
糖尿病
肿瘤
代谢
细胞生物学
肿瘤免疫
发表日期：2025
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Ru(II)-based complexes containing 2-thiouracil derivatives suppress liver cancer stem cells by targeting NF-κB and Akt/mTOR signaling

含有 2-硫尿嘧啶衍生物的 Ru(II) 基复合物通过靶向 NF-κB 和 Akt/mTOR 信号抑制肝癌干细胞

期刊:Cell Death Discovery
影响因子:6.1
doi:10.1038/s41420-024-02036-w
Larissa M Bomfim, Sara P Neves, Amanda M R M Coelho, Mateus L Nogueira, Rosane B Dias, Ludmila de F Valverde, Clarissa A G Rocha, Milena B P Soares, Alzir A Batista, Rodrigo S Correa, Daniel P Bezerra
信号转导
发育与干细胞
肿瘤
肝癌
干细胞
NF-κB
PI3K/Akt
mTOR
发表日期：2024
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A novel ruthenium complex with 5-fluorouracil suppresses colorectal cancer stem cells by inhibiting Akt/mTOR signaling

一种新型钌配合物与 5-氟尿嘧啶通过抑制 Akt/mTOR 信号传导来抑制结直肠癌干细胞

期刊:Cell Death Discovery
影响因子:6.1
doi:10.1038/s41420-023-01759-6
Valdenizia R Silva, Luciano de S Santos, Maria V L de Castro, Rosane B Dias, Ludmila de F Valverde, Clarissa A G Rocha, Milena B P Soares, Claudio A Quadros, Rodrigo S Correa, Alzir A Batista, Daniel P Bezerra
信号转导
发育与干细胞
肿瘤
肠癌
干细胞
PI3K/Akt
mTOR
发表日期：2023
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