日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hyper-physiologic mechanical cues, as an osteoarthritis disease-relevant environmental perturbation, cause a critical shift in set points of methylation at transcriptionally active CpG sites in neo-cartilage organoids

超生理机械线索作为与骨关节炎疾病相关的环境扰动,导致新软骨类器官中转录活性 CpG 位点甲基化设定点发生关键转变

Niek G C Bloks #, Amanda Dicks #, Zainab Harissa, Rob G H H Nelissen, Ghazaleh Hajmousa, Yolande F M Ramos, Rodrigo Coutinho de Almeida, Farshid Guilak #, Ingrid Meulenbelt #

Hyper-physiologic mechanical cues, as an osteoarthritis disease relevant environmental perturbation, cause a critical shift in set-points of methylation at transcriptionally active CpG sites in neo-cartilage organoids

超生理机械线索作为与骨关节炎疾病相关的环境扰动,导致新软骨类器官中转录活性 CpG 位点甲基化设定点发生关键转变

Niek Gc Bloks, Amanda Dicks, Zainab Harissa, Rob Ghh Nelissen, Ghazaleh Hajmousa, Yolande Fm Ramos, Rodrigo Coutinho Almeida, Farshid Guilak, Ingrid Meulenbelt

Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis

人类多能干细胞软骨形成的单细胞转录组分析

Chia-Lung Wu # ,Amanda Dicks # ,Nancy Steward ,Ruhang Tang ,Dakota B Katz ,Yun-Rak Choi ,Farshid Guilak

Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells

来自人类诱导性多能干细胞的软骨:与来自软骨细胞和骨髓间充质基质细胞的新软骨的比较

Alejandro Rodríguez Ruiz, Amanda Dicks, Margo Tuerlings, Koen Schepers, Melissa van Pel, Rob G H H Nelissen, Christian Freund, Christine L Mummery, Valeria Orlova, Farshid Guilak, Ingrid Meulenbelt, Yolande F M Ramos

Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter

使用 CRISPR-Cas9 生成的报告基因识别细胞表面标志,从人类 iPSC 中前瞻性分离软骨祖细胞

Amanda Dicks, Chia-Lung Wu, Nancy Steward, Shaunak S Adkar, Charles A Gersbach, Farshid Guilak0

Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing

通过 CRISPR-Cas9 基因组编辑产生的报告等位基因实现人类诱导性多能干细胞的分步软骨形成和纯化

Shaunak S Adkar, Chia-Lung Wu, Vincent P Willard, Amanda Dicks, Adarsh Ettyreddy, Nancy Steward, Nidhi Bhutani, Charles A Gersbach, Farshid Guilak