日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Immunotherapy response induces divergent tertiary lymphoid structure morphologies in hepatocellular carcinoma

免疫疗法反应诱导肝细胞癌中出现不同的三级淋巴结构形态

Daniel H Shu ,Won Jin Ho ,Luciane T Kagohara ,Alexander Girgis ,Sarah M Shin ,Ludmila Danilova ,Jae W Lee ,Dimitrios N Sidiropoulos ,Sarah Mitchell ,Kabeer Munjal ,Kathryn Howe ,Kayla J Bendinelli ,Emma Kartalia ,Hanfei Qi ,Guanglan Mo ,Janelle Montagne ,James M Leatherman ,Tamara Y Lopez-Vidal ,Qingfeng Zhu ,Amanda L Huff ,Xuan Yuan ,Alexei Hernandez ,Erin M Coyne ,Neeha Zaidi ,Daniel J Zabransky ,Logan L Engle ,Aleksandra Ogurtsova ,Marina Baretti ,Daniel Laheru ,Jennifer N Durham ,Hao Wang ,Joel C Sunshine ,Robert J Johnston ,Julie Stein Deutsch ,Janis M Taube ,Robert A Anders ,Elizabeth M Jaffee ,Elana J Fertig ,Mark Yarchoan

CD4 T cell-activating neoantigens enhance personalized cancer vaccine efficacy

CD4 T细胞激活新抗原可增强个体化癌症疫苗的疗效

Amanda L Huff ,Gabriella Longway ,Jacob T Mitchell ,Lalitya Andaloori ,Emily Davis-Marcisak ,Fangluo Chen ,Melissa R Lyman ,Rulin Wang ,Jocelyn Mathew ,Benjamin Barrett ,Sabahat Rahman ,James Leatherman ,Mark Yarchoan ,Nilofer S Azad ,Srinivasan Yegnasubramanian ,Luciane T Kagohara ,Elana J Fertig ,Elizabeth M Jaffee ,Todd D Armstrong ,Neeha Zaidi

Oncolytic virus-mediated expansion of dual-specific CAR T cells improves efficacy against solid tumors in mice

溶瘤病毒介导的双特异性CAR-T细胞扩增可提高小鼠实体瘤的治疗效果。

Laura Evgin ,Tim Kottke ,Jason Tonne ,Jill Thompson ,Amanda L Huff ,Jacob van Vloten ,Madelyn Moore ,Josefine Michael ,Christopher Driscoll ,Jose Pulido ,Eric Swanson ,Richard Kennedy ,Matt Coffey ,Houra Loghmani ,Luis Sanchez-Perez ,Gloria Olivier ,Kevin Harrington ,Hardev Pandha ,Alan Melcher ,Rosa Maria Diaz ,Richard G Vile

Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy

溶瘤病毒疗法诱导的CSDE1新抗原生成会限制VSV复制,但可通过免疫疗法进行靶向治疗。

Timothy Kottke ,Jason Tonne ,Laura Evgin ,Christopher B Driscoll ,Jacob van Vloten ,Victoria A Jennings ,Amanda L Huff ,Brady Zell ,Jill M Thompson ,Phonphimon Wongthida ,Jose Pulido ,Matthew R Schuelke ,Adel Samson ,Peter Selby ,Elizabeth Ilett ,Mark McNiven ,Lewis R Roberts ,Mitesh J Borad ,Hardev Pandha ,Kevin Harrington ,Alan Melcher ,Richard G Vile

Implantation of a neoantigen-targeted hydrogel vaccine prevents recurrence of pancreatic adenocarcinoma after incomplete resection

植入新抗原靶向水凝胶疫苗可预防胰腺腺癌不完全切除后复发

Daniel Delitto, Daniel J Zabransky, Fangluo Chen, Elizabeth D Thompson, Jacquelyn W Zimmerman, Todd D Armstrong, James M Leatherman, Reecha Suri, Tamara Y Lopez-Vidal, Amanda L Huff, Melissa R Lyman, Samantha R Guinn, Marina Baretti, Luciane T Kagohara, Won Jin Ho, Nilofer S Azad, William R Burns, J

Oncolytic virus-derived type I interferon restricts CAR T cell therapy

溶瘤病毒衍生的I型干扰素限制了CAR-T细胞疗法

Laura Evgin ,Amanda L Huff ,Phonphimon Wongthida ,Jill Thompson ,Tim Kottke ,Jason Tonne ,Matthew Schuelke ,Katayoun Ayasoufi ,Christopher B Driscoll ,Kevin G Shim ,Pierce Reynolds ,Dileep D Monie ,Aaron J Johnson ,Matt Coffey ,Sarah L Young ,Gary Archer ,John Sampson ,Jose Pulido ,Luis Sanchez Perez ,Richard Vile

APOBEC3B-mediated corruption of the tumor cell immunopeptidome induces heteroclitic neoepitopes for cancer immunotherapy

APOBEC3B 介导的肿瘤细胞免疫肽组破坏会诱导异质新表位用于癌症免疫治疗

Christopher B Driscoll #, Matthew R Schuelke #, Timothy Kottke, Jill M Thompson, Phonphimon Wongthida, Jason M Tonne, Amanda L Huff, Amber Miller, Kevin G Shim, Amy Molan, Cynthia Wetmore, Peter Selby, Adel Samson, Kevin Harrington, Hardev Pandha, Alan Melcher, Jose S Pulido, Reuben Harris, Laura Ev

Vesicular Stomatitis Virus Encoding a Destabilized Tumor Antigen Improves Activation of Anti-tumor T Cell Responses

编码不稳定肿瘤抗原的水泡性口炎病毒可改善抗肿瘤 T 细胞反应的激活

Amanda L Huff, Laura Evgin, Jill Thompson, Tim Kottke, Christopher B Driscoll, Jason Tonne, Phonphimon Wongthida, Matthew Schuelke, Kevin G Shim, Georges Mer, Marina Ramirez-Alvarado, Richard Vile

The C Protein Is Recruited to Measles Virus Ribonucleocapsids by the Phosphoprotein

蛋白被磷蛋白募集到麻疹病毒核糖核衣壳上

Christian K Pfaller, Louis-Marie Bloyet, Ryan C Donohue, Amanda L Huff, William P Bartemes, Iris Yousaf, Erica Urzua, Mathieu Clavière, Marie Zachary, Valentin de Masson d'Autume, Sandra Carson, Adam J Schieferecke, Alyssa J Meyer, Denis Gerlier, Roberto Cattaneo

Diverse immunotherapies can effectively treat syngeneic brainstem tumors in the absence of overt toxicity

多种免疫疗法可在没有明显毒性的情况下有效治疗同源脑干肿瘤

Matthew R Schuelke, Phonphimon Wongthida, Jill Thompson, Timothy Kottke, Christopher B Driscoll, Amanda L Huff, Kevin G Shim, Matt Coffey, Jose Pulido, Laura Evgin, Richard G Vile