日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy

FG-核孔蛋白募集核输入受体来挽救 TDP-43 蛋白病的特征

Bilal Khalil, Deepak Chhangani #, Melissa C Wren #, Courtney L Smith, Jannifer H Lee, Xingli Li, Christian Puttinger, Chih-Wei Tsai, Gael Fortin, Dmytro Morderer, Junli Gao, Feilin Liu, Chun Kim Lim, Jingjiao Chen, Ching-Chieh Chou, Cara L Croft, Amanda M Gleixner, Christopher J Donnelly, Todd E Gol

NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility

NUP62 定位于 ALS/FTLD 病理组装体并导致 TDP-43 不溶性

Amanda M Gleixner, Brandie Morris Verdone, Charlton G Otte, Eric N Anderson, Nandini Ramesh, Olivia R Shapiro, Jenna R Gale, Jocelyn C Mauna, Jacob R Mann, Katie E Copley, Elizabeth L Daley, Juan A Ortega, Maria Elena Cicardi, Evangelos Kiskinis, Julia Kofler, Udai B Pandey, Davide Trotti, Christoph

RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3

Matrin-3 通过 RNA 依赖性抑制 C9orf72 ALS/FTD 相关神经变性

Nandini Ramesh, Elizabeth L Daley, Amanda M Gleixner, Jacob R Mann, Sukhleen Kour, Darilang Mawrie, Eric N Anderson, Julia Kofler, Christopher J Donnelly, Evangelos Kiskinis, Udai Bhan Pandey

Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization

Muscleblind 通过调节应激颗粒动力学和 SMN 定位来调节 FUS 毒性

Ian Casci, Karthik Krishnamurthy, Sukhleen Kour, Vadreenath Tripathy, Nandini Ramesh, Eric N Anderson, Lara Marrone, Rogan A Grant, Stacie Oliver, Lauren Gochenaur, Krishani Patel, Jared Sterneckert, Amanda M Gleixner, Christopher J Donnelly, Marc-David Ruepp, Antonella M Sini, Emanuela Zuccaro, Mar

RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43

RNA 结合可拮抗 TDP-43 的神经毒性相变

Jacob R Mann, Amanda M Gleixner, Jocelyn C Mauna, Edward Gomes, Michael R DeChellis-Marks, Patrick G Needham, Katie E Copley, Bryan Hurtle, Bede Portz, Noah J Pyles, Lin Guo, Christopher B Calder, Zachary P Wills, Udai B Pandey, Julia K Kofler, Jeffrey L Brodsky, Amantha Thathiah, James Shorter, Chr

N-Acetyl-l-Cysteine Protects Astrocytes against Proteotoxicity without Recourse to Glutathione

N-乙酰-l-半胱氨酸保护星形胶质细胞免受蛋白质毒性,而无需依赖谷胱甘肽

Amanda M Gleixner, Daniel F Hutchison, Sara Sannino, Tarun N Bhatia, Lillian C Leak, Patrick T Flaherty, Peter Wipf, Jeffrey L Brodsky, Rehana K Leak

Astrocytes Surviving Severe Stress Can Still Protect Neighboring Neurons from Proteotoxic Injury

星形胶质细胞在严重压力下仍能保护邻近的神经元免受蛋白毒性损伤

Amanda M Gleixner, Jessica M Posimo, Deepti B Pant, Matthew P Henderson, Rehana K Leak

Heat shock protein defenses in the neocortex and allocortex of the telencephalon

端脑新皮质和异皮质中的热休克蛋白防御

Jessica M Posimo, Justin N Weilnau, Amanda M Gleixner, Matthew T Broeren, Nicole L Weiland, Jeffrey L Brodsky, Peter Wipf, Rehana K Leak