日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In Vitro Antiviral Properties of Two Recombinant Sendai Virus Vectors Encoding ORFV 011 and ORFV 059 Genes

编码 ORFV 011 和 ORFV 059 基因的两种重组仙台病毒载体的体外抗病毒特性

Gómez, Álex; Glaria, Idoia; Moncayola, Irati; Puzol, Leonor; Arriazu, Laura; Calero, Ainhoa; de Blas, Ignacio; Nazábal, Mikel; Hualde, Itziar; Lee, Benhur; Luján, Lluís; Amann, Ralf; Echeverría, Irache; Reina, Ramsés

Broadening SARS-CoV-2 Immunity by Combining ORFV and Protein-Based Vaccines.

通过结合 ORFV 和蛋白质疫苗来扩大 SARS-CoV-2 免疫力。

Reguzova Alena, Müller Melanie, Fandrich Madeleine, Dulovic Alex, Amann Ralf

Orf virus-based vectors induce potent germinal center B cell, Tfh cell, and CD8(+) T cell responses

基于羊口疮病毒的载体可诱导强效的生发中心B细胞、Tfh细胞和CD8(+) T细胞反应。

Kastner, Anna Lena; Müller, Melanie; Marx, Anna-Friederike; Dimitrova, Mirela; Wagner, Ingrid; Merkler, Doron; Amann, Ralf; Pinschewer, Daniel D

Advancing ORFV-Based Therapeutics to the Clinical Stage

将基于ORFV的疗法推进到临床阶段

Helmold, Matthias; Amann, Ralf

A novel orf virus vector-based COVID-19 booster vaccine shows cross-neutralizing activity in the absence of anti-vector neutralizing immunity

一种基于新型羊痘病毒载体的COVID-19加强疫苗在缺乏抗载体中和免疫的情况下显示出交叉中和活性。

Klinkardt, Ute; Schunk, Mirjam; Ervin, John; Schindler, Christoph; Sugimoto, Danny; Rankin, Bruce; Amann, Ralf; Monti, Martina; Kutschenko, Anna; Schumacher, Carsten; Huber, Kristina; Zeder, Andreas; Heikkila, Nelli; Didierlaurent, Arnaud M; Schwarz, Sylvia E; Derouazi, Madiha

Pharmacokinetic and Environmental Risk Assessment of Prime-2-CoV, a Non-Replicating Orf Virus-Based Vaccine against SARS-CoV-2

Prime-2-CoV(一种基于非复制型羊痘病毒的SARS-CoV-2疫苗)的药代动力学和环境风险评估

Metz, Carina; Haug, Verena; Müller, Melanie; Amann, Ralf

First-in-Human Phase I Trial to Assess the Safety and Immunogenicity of an Orf Virus-Based COVID-19 Vaccine Booster.

首次人体 I 期试验,评估基于羊痘病毒的 COVID-19 疫苗加强针的安全性和免疫原性

Esen Meral, Fischer-Herr Johanna, Gabor Julian Justin, Gaile Johanna Marika, Fleischmann Wim Alexander, Smeenk Geerten Willem, de Moraes Roberta Allgayer, Bélard Sabine, Calle Carlos Lamsfus, Woldearegai Tamirat Gebru, Egger-Adam Diane, Haug Verena, Metz Carina, Reguzova Alena, Löffler Markus W, Balode Baiba, Matthies Lars C, Ramharter Michael, Amann Ralf, Kremsner Peter G

Orf Virus-Based Vectors Preferentially Target Professional Antigen-Presenting Cells, Activate the STING Pathway and Induce Strong Antigen-Specific T Cell Responses.

基于羊痘病毒的载体优先靶向专业抗原呈递细胞,激活 STING 通路,并诱导强烈的抗原特异性 T 细胞反应

Müller Melanie, Reguzova Alena, Löffler Markus W, Amann Ralf

A Novel Orf Virus D1701-VrV-Based Dengue Virus (DENV) Vaccine Candidate Expressing HLA-Specific T Cell Epitopes: A Proof-of-Concept Study.

一种基于新型羊痘病毒D1701-VrV的登革病毒(DENV)候选疫苗,表达HLA特异性T细胞表位:概念验证研究

Reguzova Alena, Fischer Nico, Müller Melanie, Salomon Ferdinand, Jaenisch Thomas, Amann Ralf