日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids.

MEF2C自闭症患者hiPSC神经元和脑类器官中miRNA表达和兴奋失调

期刊:Molecular Psychiatry
影响因子:10.1
doi:10.1038/s41380-024-02761-9
Trudler Dorit, Ghatak Swagata, Bula Michael, Parker James, Talantova Maria, Luevanos Melissa, Labra Sergio, Grabauskas Titas, Noveral Sarah Moore, Teranaka Mayu, Schahrer Emily, Dolatabadi Nima, Bakker Clare, Lopez Kevin, Sultan Abdullah, Patel Parth, Chan Agnes, Choi Yongwook, Kawaguchi Riki, Stankiewicz Pawel, Garcia-Bassets Ivan, Kozbial Piotr, Rosenfeld Michael G, Nakanishi Nobuki, Geschwind Daniel H, Chan Shing Fai, Lin Wei, Schork Nicholas J, Ambasudhan Rajesh, Lipton Stuart A
神经科学
3D/类器官
miRNA
发表日期：2025
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NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models

NitroSynapsin可改善阿尔茨海默病hiPSC模型中过度同步的神经网络活动

期刊:Molecular Psychiatry
影响因子:9.6
doi:10.1038/s41380-020-0776-7
Swagata Ghatak ，Nima Dolatabadi ，Richard Gao ，Yin Wu ，Henry Scott ，Dorit Trudler ，Abdullah Sultan ，Rajesh Ambasudhan ，Tomohiro Nakamura ，Eliezer Masliah ，Maria Talantova ，Bradley Voytek ，Stuart A Lipton
阿尔茨海默症
发表日期：2021
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Soluble α-synuclein-antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia

可溶性α-突触核蛋白-抗体复合物激活hiPSC衍生小胶质细胞中的NLRP3炎症小体

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2025847118
Trudler, Dorit; Nazor, Kristopher L; Eisele, Yvonne S; Grabauskas, Titas; Dolatabadi, Nima; Parker, James; Sultan, Abdullah; Zhong, Zhenyu; Goodwin, Marshall S; Levites, Yona; Golde, Todd E; Kelly, Jeffery W; Sierks, Michael R; Schork, Nicholas J; Karin, Michael; Ambasudhan, Rajesh; Lipton, Stuart A
胶质细胞
炎症
炎性小体
炎症/感染
神经科学
LRP3
NLRP3
细胞生物学
炎性小体
免疫/内分泌
发表日期：2021
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Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs isogenic controls

阿尔茨海默病中过度兴奋的机制：hiPSC衍生神经元和脑类器官与同基因对照组的比较

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.50333
Swagata Ghatak # ，Nima Dolatabadi # ，Dorit Trudler ，XiaoTong Zhang ，Yin Wu ，Madhav Mohata ，Rajesh Ambasudhan ，Maria Talantova ，Stuart A Lipton
神经科学
3D/类器官
阿尔茨海默症
发表日期：2019
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Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein

线粒体外膜上的心磷脂暴露可调节α-突触核蛋白

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-018-03241-9
Tammy Ryan ，Vladimir V Bamm ，Morgan G Stykel ，Carla L Coackley ，Kayla M Humphries ，Rhiannon Jamieson-Williams ，Rajesh Ambasudhan ，Dick D Mosser ，Stuart A Lipton ，George Harauz ，Scott D Ryan
线粒体
神经科学
发表日期：2018
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Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer's disease

鉴定一种识别阿尔茨海默病小鼠模型中脑血管变化的肽

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-017-01096-0
Aman P Mann, Pablo Scodeller, Sazid Hussain, Gary B Braun, Tarmo Mölder, Kadri Toome, Rajesh Ambasudhan, Tambet Teesalu, Stuart A Lipton, Erkki Ruoslahti
神经
阿尔茨海默症
Mouse
发表日期：2017
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S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson's Disease Models

PINK1的S-亚硝基化减弱了基于hiPSC的帕金森病模型中PINK1/Parkin依赖的线粒体自噬

期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2017.10.068
Oh, Chang-Ki; Sultan, Abdullah; Platzer, Joseph; Dolatabadi, Nima; Soldner, Frank; McClatchy, Daniel B; Diedrich, Jolene K; Yates, John R 3rd; Ambasudhan, Rajesh; Nakamura, Tomohiro; Jaenisch, Rudolf; Lipton, Stuart A
PINK1
帕金森
NK1
神经科学
线粒体
Parkin
自噬
发表日期：2017
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Elevated glucose and oligomeric β-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation

高血糖和寡聚β-淀粉样蛋白通过异常蛋白S-亚硝基化的共同途径破坏突触。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/ncomms10242
Akhtar, Mohd Waseem; Sanz-Blasco, Sara; Dolatabadi, Nima; Parker, James; Chon, Kevin; Lee, Michelle S; Soussou, Walid; McKercher, Scott R; Ambasudhan, Rajesh; Nakamura, Tomohiro; Lipton, Stuart A
神经科学
发表日期：2016
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Hydrogen Sulfide--Mechanisms of Toxicity and Development of an Antidote

硫化氢——毒性机制及解毒剂的开发

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/srep20831
Jingjing Jiang, Adriano Chan, Sameh Ali, Arindam Saha, Kristofer J Haushalter, Wai-Ling Macrina Lam, Megan Glasheen, James Parker, Matthew Brenner, Sari B Mahon, Hemal H Patel, Rajesh Ambasudhan, Stuart A Lipton, Renate B Pilz, Gerry R Boss
信号转导
发表日期：2016
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Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases

异常的蛋白质S-亚硝基化与神经退行性疾病的病理生理学有关。

期刊:Neurobiology of Disease
影响因子:5.6
doi:10.1016/j.nbd.2015.03.017
Nakamura, Tomohiro; Prikhodko, Olga A; Pirie, Elaine; Nagar, Saumya; Akhtar, Mohd Waseem; Oh, Chang-Ki; McKercher, Scott R; Ambasudhan, Rajesh; Okamoto, Shu-ichi; Lipton, Stuart A
神经科学
发表日期：2015
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