日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo

体外小结肠中时空分辨的结肠直肠癌发生

L Francisco Lorenzo-Martín #, Tania Hübscher #, Amber D Bowler, Nicolas Broguiere, Jakob Langer, Lucie Tillard, Mikhail Nikolaev, Freddy Radtke, Matthias P Lutolf

Bcl-xL targeting eliminates ageing tumor-promoting neutrophils and inhibits lung tumor growth

靶向Bcl-xL可清除衰老的促肿瘤中性粒细胞并抑制肺肿瘤生长

Anita Bodac ,Abdullah Mayet ,Sarika Rana ,Justine Pascual ,Amber D Bowler ,Vincent Roh ,Nadine Fournier ,Ligia Craciun ,Pieter Demetter ,Freddy Radtke ,Etienne Meylan

Neutrophils suppress tumor-infiltrating T cells in colon cancer via matrix metalloproteinase-mediated activation of TGFβ

中性粒细胞通过基质金属蛋白酶介导的 TGFβ 激活抑制结肠癌中的肿瘤浸润 T 细胞

Markus Germann, Nadine Zangger, Marc-Olivier Sauvain, Christine Sempoux, Amber D Bowler, Pratyaksha Wirapati, Lana E Kandalaft, Mauro Delorenzi, Sabine Tejpar, George Coukos, Freddy Radtke

Combining the Allosteric Inhibitor Asciminib with Ponatinib Suppresses Emergence of and Restores Efficacy against Highly Resistant BCR-ABL1 Mutants

将变构抑制剂 Asciminib 与 Ponatinib 联合使用可抑制高耐药性 BCR-ABL1 突变体的出现并恢复其疗效

Christopher A Eide, Matthew S Zabriskie, Samantha L Savage Stevens, Orlando Antelope, Nadeem A Vellore, Hein Than, Anna Reister Schultz, Phillip Clair, Amber D Bowler, Anthony D Pomicter, Dongqing Yan, Anna V Senina, Wang Qiang, Todd W Kelley, Philippe Szankasi, Michael C Heinrich, Jeffrey W Tyner, 

shRNA library screening identifies nucleocytoplasmic transport as a mediator of BCR-ABL1 kinase-independent resistance

shRNA 文库筛选确定核质运输是 BCR-ABL1 激酶非依赖性抗性的介质

Jamshid S Khorashad, Anna M Eiring, Clinton C Mason, Kevin C Gantz, Amber D Bowler, Hannah M Redwine, Fan Yu, Ira L Kraft, Anthony D Pomicter, Kimberly R Reynolds, Anthony J Iovino, Matthew S Zabriskie, William L Heaton, Srinivas K Tantravahi, Michael Kauffman, Sharon Shacham, Alex Chenchik, Kyle Bo