日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Functional immune responses induced by a capsid assembly modulator in chronic hepatitis B virus-infected humanized mice.

衣壳组装调节剂在慢性乙型肝炎病毒感染的人源化小鼠中诱导的功能性免疫反应。

期刊:Cell Host & Microbe
影响因子:18.7
doi:10.1016/j.chom.2025.12.001
Fernandes Priyanka, Wang Yidan, Doisne Jean-Marc, Thaller Anna, Fiquet Oriane, Dailleux Rémy, Amblard Franck, Testoni Barbara, Aronthippaitoon Yada, Mouquet Hugo, Sureau Camille, Reyné Bastien, Tiezzi Camilla, Soussan Patrick, Levrero Massimo, Zoulim Fabien, Schinazi Raymond F, Strick-Marchand Helene
炎症/感染
免疫/内分泌
肝炎
微生物学
发表日期：2026
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Prodrug strategies in developing antiviral nucleoside analogs

抗病毒核苷类似物开发中的前药策略

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d5md00810g
Suresh, R Rama; Abuduani, Tuniyazi; Kasthuri, Mahesh; Chen, Zhe; Tber, Zahira; Loubidi, Mohammed; Zhang, HongWang; Zhou, Longhu; Zhou, Shaoman; Li, Chenwei; Kumari, Amita; Tao, Sijia; Wiseman, John M; Hurwitz, Selwyn J; Amblard, Franck; Schinazi, Raymond F
微生物学
发表日期：2026
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The 2'-α-Fluoro,2'-β-Bromo uridine phosphoramidate prodrug (2-BFU) reduces dengue virus replication and attenuates infection-induced thrombocytopenia In Vivo

2'-α-氟-2'-β-溴尿苷磷酰胺前药（2-BFU）可降低登革病毒复制并减轻体内感染引起的血小板减少症。

期刊:Medical Microbiology and Immunology
影响因子:3
doi:10.1007/s00430-026-00868-0
Dias, Angélica Samer Lallo; Santos, Felipe Rocha da Silva; Martins, Jenniffer Ramos; Batista, Viviane Lima; da Fonseca, Talita Cristina Martins; Soldati, Leticia Pereira; Queiroz-Junior, Celso Martins; Amblard, Franck; Schinazi, Raymond F; Teixeira, Mauro Martins; Costa, Vivian Vasconcelos
炎症/感染
血小板
微生物学
发表日期：2026
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Strategy to overcome a nirmatrelvir resistance mechanism in the SARS-CoV-2 nsp5 protease

克服SARS-CoV-2 nsp5蛋白酶中尼尔马特雷韦耐药机制的策略

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adv8875
Neilsen, Grace; Lan, Shuiyun; Slack, Ryan L; Lorson, Zachary C; Emanuelli Castaner, Andres; Lee, Rachel; Edwards, Kristin G; Zhang, Huanchun; Lee, Jasper; Cantara, William A; Cilento, Maria E; Zhang, Hongwang; De, Ramyani; Amblard, Franck; Tedbury, Philip R; Kirby, Karen A; Schinazi, Raymond F; Sarafianos, Stefan G
SARS-CoV-2
发表日期：2025
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1'-Cyanocytidine-5'-isobutyryl is a potent SARS-CoV-2 inhibitor in culture and infected Syrian hamsters

1'-氰胞苷-5'-异丁酰基在体外培养和感染叙利亚仓鼠中均表现出对SARS-CoV-2的强效抑制作用。

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adz5913
Amblard, Franck; Kasthuri, Mahesh; LeCher, Julia C; Tao, Sijia; De, Ramyani; Abdelnabi, Rana; Marko, Ingrid; Zhou, Longhu; Li, Chengwei; Shi, Junxing; Goh, Shu Ling; Downs-Bowen, Jessica; Bassit, Leda; Hurwitz, Selwyn; Zandi, Keivan; McBrayer, Tamara; Weynand, Birgit; Johnson, Kenneth A; Neyts, Johan; Schinazi, Raymond F
炎症/感染
SARS-CoV-2
发表日期：2025
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Novel Dimeric Capsid Assembly Modulators as a Unique Class of Highly Potent Anti-HBV Agents

新型二聚体衣壳组装调节剂作为一类独特的高效抗乙肝病毒药物

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c01983
Amblard, Franck; Chen, Zhe; Kra, Kalouna; Patel, Dharmeshkumar; Bassit, Leda; Gargowitsch, Laetitia; Degrouard, Jéril; Rat, Virgile; Arteni, Ana-Andreea; Matthews, Lauren; Ravichandran, Shreya M; Jiang, Alfred; Athanasiadis, Antonis; Dangas, Georgios; Abate, Maedot; Tresset, Guillaume; Pronost, Julien; Salman, Mohammad; Verma, Kiran; Kirby, Karen A; Michailidis, Eleftherios; Rocquigny, Hugues de; Durantel, David; Bressanelli, Stéphane; Sarafianos, Stefan G; Schinazi, Raymond F
微生物学
发表日期：2025
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Erratum for Dinh et al., "The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir"

更正：Dinh 等人，“病毒对变构 HIV-1 整合酶抑制剂 pirmitegravir 产生耐药性的结构和机制基础”

期刊:mBio
影响因子:4.7
doi:10.1128/mbio.03106-25
Dinh, Tung; Tber, Zahira; Rey, Juan S; Mengshetti, Seema; Annamalai, Arun S; Haney, Reed; Briganti, Lorenzo; Amblard, Franck; Fuchs, James R; Cherepanov, Peter; Kim, Kyungjin; Schinazi, Raymond F; Perilla, Juan R; Kim, Baek; Kvaratskhelia, Mamuka
HIV
微生物学
发表日期：2025
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Combating yellow fever virus with 7-deaza-7-fluoro-2'-C-methyladenosine

用7-脱氮-7-氟-2'-C-甲基腺苷对抗黄热病毒

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.01889-24
LeCher, Julia C; Costa, Vivian Vasconcelos; Rust, Lauren N; Bassit, Leda C; Patel, Dharmeshkumar; Rezaei, Sahar; Moua, Justin; Santos, Felipe Rocha da Silva; Goncalves, Matheus Rodrigues; Queroz-Junior, Celso Martins; Marim, Fernanda Martins; Zhou, Longhu; Lee, Sujin; McBrayer, Tamara; De, Ramyani; Azadi, Niloufar; Salman, Mohammad; Zandi, Keivan; Amblard, Franck; Burwitz, Benjamin; Teixeira, Mauro M; Schinazi, Raymond F
微生物学
发表日期：2025
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Discovery of broad-spectrum antivirals targeting viral proteases using in silico structural modeling and cellular analysis

利用计算机结构建模和细胞分析发现靶向病毒蛋白酶的广谱抗病毒药物

期刊:Antiviral Research
影响因子:4
doi:10.1016/j.antiviral.2025.106245
Patel, Dharmeshkumar; De, Ramyani; Azadi, Niloufar; Lee, Sujin; Shooter, Savannah; Amichai, Sarah; Zhou, Shaoman; Monroe, Danielle; Mahanke, Cameron; McBrayer, Tamara R; Muczynski, Michael; Al-Homoudi, Abdullah; Engel, Joseph; Bochkov, Yury A; Gern, James E; Kovari, Ladislau C; Amblard, Franck; Schinazi, Raymond F
微生物学
细胞生物学
发表日期：2025
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Mechanism of Inhibition of the Active Triphosphate Form of 2'-α-Fluoro,2'-β-bromouridine against Yellow Fever Virus RNA-Dependent RNA Polymerase

2'-α-氟-2'-β-溴尿苷活性三磷酸形式抑制黄热病毒RNA依赖性RNA聚合酶的机制

期刊:ACS Infectious Diseases
影响因子:3.8
doi:10.1021/acsinfecdis.5c00086
Gordon, Calvin Joel; Walker, Simon Maximus; LeCher, Julia Christine; Amblard, Franck; Schinazi, Raymond Felix; Götte, Matthias
微生物学
发表日期：2025
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