Carfentanil stabilizes µ opioid receptor conformations that are ultra-efficient in inhibiting cAMP, resistant to naloxone or nalmefene but sensitive to naltrexone.

卡芬太尼可稳定μ阿片受体构象，该构象能超有效地抑制cAMP，对纳洛酮或纳美芬有抗性，但对纳曲酮敏感