日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

FDXR variants cause adrenal insufficiency and atypical sexual development

FDXR 变异可导致肾上腺功能不全和异常性发育

Emanuele Pignatti, Jesse Slone, María Ángeles Gómez Cano, Teresa Margaret Campbell, Jimmy Vu, Kay-Sara Sauter, Amit V Pandey, Francisco Martínez-Azorín, Marina Alonso-Riaño, Derek E Neilson, Nicola Longo, Therina du Toit, Clarissa D Voegel, Taosheng Huang, Christa E Flück

Effect of Essential Oil Components on the Activity of Steroidogenic Cytochrome P450

精油成分对类固醇生成细胞色素P450活性的影响

Katyayani Sharma, Angelo Lanzilotto, Jibira Yakubu, Søren Therkelsen, Clarissa Daniela Vöegel, Therina Du Toit, Flemming Steen Jørgensen, Amit V Pandey

Exploring Novel Variants of the Cytochrome P450 Reductase Gene (POR) from the Genome Aggregation Database by Integrating Bioinformatic Tools and Functional Assays

通过整合生物信息学工具和功能分析从基因组聚集数据库中探索细胞色素 P450 还原酶基因 (POR) 的新变体

Maria Natalia Rojas Velazquez, Søren Therkelsen, Amit V Pandey

Loss of Protein Stability and Function Caused by P228L Variation in NADPH-Cytochrome P450 Reductase Linked to Lower Testosterone Levels

NADPH-细胞色素 P450 还原酶 P228L 变异导致蛋白质稳定性和功能丧失,与睾酮水平降低有关

Maria Natalia Rojas Velazquez, Mathias Noebauer, Amit V Pandey

Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase

通过小分子配体结合 P450 氧化还原酶实现细胞色素 P450 介导的偏向性代谢

Simon Bo Jensen, Sara Thodberg, Shaheena Parween, Matias E Moses, Cecilie C Hansen, Johannes Thomsen, Magnus B Sletfjerding, Camilla Knudsen, Rita Del Giudice, Philip M Lund, Patricia R Castaño, Yanet G Bustamante, Maria Natalia Rojas Velazquez, Flemming Steen Jørgensen, Amit V Pandey, Tomas Laursen

Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy

降低 FASN 表达可使急性髓系白血病细胞对分化疗法更加敏感

Magali Humbert ,Kristina Seiler ,Severin Mosimann ,Vreni Rentsch ,Katyayani Sharma ,Amit V Pandey ,Sharon L McKenna ,Mario P Tschan

Characterization of Mutations Causing CYP21A2 Deficiency in Brazilian and Portuguese Populations

巴西和葡萄牙人群中 CYP21A2 缺陷突变的特征

Mayara J Prado, Shripriya Singh, Rodrigo Ligabue-Braun, Bruna V Meneghetti, Thaiane Rispoli, Cristiane Kopacek, Karina Monteiro, Arnaldo Zaha, Maria L R Rossetti, Amit V Pandey

3β-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3α-epimer by hepatic metabolism

3β-异贝胆酸在肝脏代谢过程中会异构化为 3α-异构体,从而有效激活法呢醇 X 受体 (FXR)

Alzbeta Stefela, Miroslav Kaspar, Martin Drastik, Ondrej Holas, Milos Hroch, Tomas Smutny, Josef Skoda, Miriama Hutníková, Amit V Pandey, Stanislav Micuda, Eva Kudova, Petr Pavek

Characterization of Two Novel Variants of the Steroidogenic Acute Regulatory Protein Identified in a Girl with Classic Lipoid Congenital Adrenal Hyperplasia

在患有典型脂质性先天性肾上腺增生症的女孩中发现的两种新型类固醇生成急性调节蛋白变体的表征

Efstathios Katharopoulos, Natascia Di Iorgi, Paula Fernandez-Alvarez, Amit V Pandey, Michael Groessl, Shraddha Dubey, Núria Camats, Flavia Napoli, Giuseppa Patti, Marilea Lezzi, Mohamad Maghnie, Christa E Flück

Genes and proteins of the alternative steroid backdoor pathway for dihydrotestosterone synthesis are expressed in the human ovary and seem enhanced in the polycystic ovary syndrome

用于双氢睾酮合成的替代类固醇后门途径的基因和蛋白质在人类卵巢中表达,并且在多囊卵巢综合征中似乎得到增强

Nesa Marti, José A Galván, Amit V Pandey, Mafalda Trippel, Coya Tapia, Michel Müller, Aurel Perren, Christa E Flück