日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Investigating the Effect of Increased TMEM106B in a Tauopathy Model

研究TMEM106B增加对tau蛋白病模型的影响

Patel, Haritosh; Huang, Yu Xuan; Dengiz, Duygu; Pravdivtseva, Mariya; Jansen, Olav; Quandt, Eckhard; Aizenberg, Joanna; de Haro, Maria; Fadel, Omar El; Stephens, Morgan Catherine; Lee, Kwanghyuk Danny; Lichtarge, Olivier; Al‐Ramahi, Ismael; Botas, Juan; Li‐Kroeger, David; Al‐Ramahi, Ismael; Smith, Nathaniel; Marella, Aditi; Amoh, Bismark K; Saladi, Saathwik; Marfathia, Ruhee; Botas, Juan; Seyfried, Nicholas T; Levey, Allan I; Shulman, Joshua M; Amador, Adulfo Anaya; Aguirre‐Lamus, Isabella; Timperman, Dylan Lawrence; Kim, Peter; Jankowsky, Joanna L; Al‐Ramahi, Ismael

Longitudinal multi-omics in alpha-synuclein Drosophila model discriminates disease- from age-associated pathologies in Parkinson's disease.

α-突触核蛋白果蝇模型中的纵向多组学可区分帕金森病中的疾病相关病理和年龄相关病理

Moore Justin, Wu Timothy, Dhindsa Justin, El Fadel Omar, Le Anh, Perez Alma, Amoh Bismark, Tarkunde Akash, Zhu Katy F, Avalos Matthew, Dammer Eric B, Duong Duc M, Seyfried Nicholas T, Shulman Joshua M, Al-Ramahi Ismael, Botas Juan

The SMOC1 proteomics network controls signaling modalities, brain homeostasis and toxicity in fly Alzheimer's disease models

SMOC1蛋白质组学网络调控果蝇阿尔茨海默病模型中的信号传导模式、脑稳态和毒性

Byeon, Yen Ji Julia; Islamaj, Rezarta; Yeganova, Lana; Wilbur, W John; Lu, Zhiyong; Brody, Lawrence C; Bonham, Vence L; Li‐Kroeger, David; Al‐Ramahi, Ismael; Smith, Nathaniel; Marella, Aditi; Amoh, Bismark K; Saladi, Saathwik; Marfathia, Ruhee; Botas, Juan; Seyfried, Nicholas T; Levey, Allan I; Shulman, Joshua M

Computational and functional prioritization identifies genes that rescue behavior and reduce tau protein in fly and human cell models of Alzheimer disease

计算和功能优先级排序可识别出在阿尔茨海默病果蝇和人类细胞模型中能够挽救行为并减少tau蛋白的基因。

Stephens, Morgan C; Li, Jiayang; Mair, Megan; Moore, Justin; Zhu, Katy; Tarkunde, Akash; Amoh, Bismark; Perez, Alma M; Bhakare, Arya; Guo, Fangfei; Shulman, Joshua M; Al-Ramahi, Ismael; Botas, Juan

Heavy Chains, Heavy Consequences: A Case of Concomitant Heavy Chain Amyloidosis and Heavy Chain Deposition Disease

重链,重后果:一例伴随性重链淀粉样变性和重链沉积病

Amoh, Bismark Kojo; Ghanem, Ghadi; Zuckerman, Jonathan E; Bruss, Zachary; Chuang, Kelley

The SMOC1 proteomics network controls signaling modalities, brain homeostasis and toxicity in fly Alzheimer's disease models

SMOC1蛋白质组学网络调控果蝇阿尔茨海默病模型中的信号传导模式、脑稳态和毒性

Navarro, Juan A; Schneuwly, Stephan; Li‐Kroeger, David; Al‐Ramahi, Ismael; Smith, Nathaniel; Marella, Aditi; Amoh, Bismark K; Saladi, Saathwik; Marfathia, Ruhee; Botas, Juan; Seyfried, Nicholas T; Levey, Allan I; Shulman, Joshua M

Evolutionary Theory and Machine Learning: New Inroads Into Sex‐specific AD Susceptibility Genes and Pathways Significantly Improve Risk Prediction

进化论与机器学习:性别特异性阿尔茨海默病易感基因和通路研究的新进展显著提高了风险预测能力

Perlova, Ksenia; Schmidt, Claudia C; Fink, Gereon R; Weiss, Peter H; Zhao, Pinghan; Fadel, Omar El; Le, Anh; Mangleburg, Carl Grant; Wu, Timothy; Dhindsa, Justin; Amoh, Bismark K; Marella, Aditi Sai; Li, Yarong; Seyfried, Nicholas T; Levey, Allan I; Liu, Zhandong; Al‐Ramahi, Ismael; Botas, Juan; Shulman, Joshua M; Li‐Kroeger, David; Al‐Ramahi, Ismael; Smith, Nathaniel; Marella, Aditi; Amoh, Bismark K; Saladi, Saathwik; Botas, Juan; Seyfried, Nicholas T; Levey, Allan I; Shulman, Joshua M; Al‐Ramahi, Ismael; Asmussen, Jenn; Botas, Juan; Katsonis, Panagiotis; Lagiesetty, Yashwanth; Lee, Kwanghyuk Danny; Nazem, Fatemeh; Samieinasab, Maryam; Wang, Chen; Wilhelm, Kevin; Lichtarge, Olivier

Systems genetic dissection of Alzheimer’s disease brain gene expression networks

阿尔茨海默病脑基因表达网络的系统遗传学解析

Ile, Kristina E; Renault, Andrew D; Zhao, Pinghan; Fadel, Omar El; Le, Anh; Mangleburg, Carl Grant; Wu, Timothy; Dhindsa, Justin; Amoh, Bismark K; Marella, Aditi Sai; Li, Yarong; Seyfried, Nicholas T; Levey, Allan I; Liu, Zhandong; Al‐Ramahi, Ismael; Botas, Juan; Shulman, Joshua M

Integration of transcriptome-wide association study with neuronal dysfunction assays provides functional genomics evidence for Parkinson's disease genes

将全转录组关联研究与神经元功能障碍检测相结合,为帕金森病基因提供了功能基因组学证据。

Li, Jiayang; Amoh, Bismark Kojo; McCormick, Emma; Tarkunde, Akash; Zhu, Katy Fan; Perez, Alma; Mair, Megan; Moore, Justin; Shulman, Joshua M; Al-Ramahi, Ismael; Botas, Juan