日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mammalian D-Cysteine controls insulin secretion in the pancreas

哺乳动物 D-半胱氨酸控制胰腺胰岛素的分泌

Robin Roychaudhuri, Timothy West, Soumyaroop Bhattacharya, Harry G Saavedra, Hangnoh Lee, Lauren Albacarys, Moataz M Gadalla, Mario Amzel, Peixin Yang, Solomon H Snyder

Structural insights into the mechanism of the sodium/iodide symporter

钠/碘转运体机制的结构洞察

Silvia Ravera, Juan Pablo Nicola, Glicella Salazar-De Simone, Fred J Sigworth, Erkan Karakas, L Mario Amzel, Mario A Bianchet, Nancy Carrasco

Development of high-affinity nanobodies specific for NaV1.4 and NaV1.5 voltage-gated sodium channel isoforms

针对 NaV1.4 和 NaV1.5 电压门控钠通道异构体的高亲和力纳米抗体的开发

Lakshmi Srinivasan, Vanina Alzogaray, Dakshnamurthy Selvakumar, Sara Nathan, Jesse B Yoder, Katharine M Wright, Sebastián Klinke, Justin N Nwafor, María S Labanda, Fernando A Goldbaum, Arne Schön, Ernesto Freire, Gordon F Tomaselli, L Mario Amzel, Manu Ben-Johny, Sandra B Gabelli

The Iodide Transport Defect-Causing Y348D Mutation in the Na(+)/I(-) Symporter Renders the Protein Intrinsically Inactive and Impairs Its Targeting to the Plasma Membrane

导致碘离子转运缺陷的Na(+)/I(-)同向转运蛋白中的Y348D突变使该蛋白本身失去活性,并损害其向质膜的定位。

Reyna-Neyra, Andrea; Jung, Lara; Chakrabarti, Mayukh; Suárez, Mikel X; Amzel, L Mario; Carrasco, Nancy

Structural basis of cytoplasmic NaV1.5 and NaV1.4 regulation

细胞质NaV1.5和NaV1.4调控的结构基础

Nathan, Sara; Gabelli, Sandra B; Yoder, Jesse B; Srinivasan, Lakshmi; Aldrich, Richard W; Tomaselli, Gordon F; Ben-Johny, Manu; Amzel, L Mario

Allosteric regulation of mammalian Na(+)/I(-) symporter activity by perchlorate

高氯酸盐对哺乳动物Na(+)/I(-)同向转运蛋白活性的变构调节

Llorente-Esteban, Alejandro; Manville, Rían W; Reyna-Neyra, Andrea; Abbott, Geoffrey W; Amzel, L Mario; Carrasco, Nancy

Bisphosphonate-Based Molecules as Potential New Antiparasitic Drugs

基于双膦酸盐的分子作为潜在的新型抗寄生虫药物

Branco Santos, Joice Castelo; de Melo, Jonathas Alves; Maheshwari, Sweta; de Medeiros, Wendy Marina Toscano Queiroz; de Freitas Oliveira, Johny Wysllas; Moreno, Cláudia Jassica; Mario Amzel, L; Gabelli, Sandra B; Sousa Silva, Marcelo

Allosteric Activation of PI3Kα Results in Dynamic Access to Catalytically Competent Conformations

PI3Kα的变构激活导致其动态地获得具有催化活性的构象

Chakrabarti, Mayukh; Gabelli, Sandra B; Amzel, L Mario

Mycobacterium tuberculosis ribosomal protein S1 (RpsA) and variants with truncated C-terminal end show absence of interaction with pyrazinoic acid

结核分枝杆菌核糖体蛋白 S1 (RpsA) 及其 C 末端截短的变体与吡嗪酸无相互作用

Katherine Vallejos-Sánchez, Juan M Lopez, Ricardo Antiparra, Emily Toscano, Harry Saavedra, Daniela E Kirwan, L M Amzel, R H Gilman, Helena Maruenda, Patricia Sheen, Mirko Zimic

Identifying Structural Determinants of Product Specificity in Leishmania major Farnesyl Diphosphate Synthase

鉴定利什曼原虫法呢基二磷酸合酶产品特异性的结构决定因素

Sweta Maheshwari, Yu Seon Kim, Srinivas Aripirala, Michael Murphy, L Mario Amzel, Sandra B Gabelli