Ana Rey-Rico相关文献与解析，生知库 | 链接生命科学的每一步

Hydrogel-Guided, rAAV-Mediated IGF-I Overexpression Enables Long-Term Cartilage Repair and Protection against Perifocal Osteoarthritis in a Large-Animal Full-Thickness Chondral Defect Model at One Year In Vivo

水凝胶引导、rAAV 介导的 IGF-I 过表达可在体内一年内实现大型动物全层软骨缺损模型的长期软骨修复和对局灶性骨关节炎的预防

doi:10.1002/adma.202008451

Johanna Maihöfer, Henning Madry, Ana Rey-Rico, Jagadeesh K Venkatesan, Lars Goebel, Gertrud Schmitt, Susanne Speicher-Mentges, Xiaoyu Cai, Weikun Meng, David Zurakowski, Michael D Menger, Matthias W Laschke, Magali Cucchiarini

Enhanced Chondrogenic Differentiation Activities in Human Bone Marrow Aspirates via sox9 Overexpression Mediated by pNaSS-Grafted PCL Film-Guided rAAV Gene Transfer

通过 pNaSS 嫁接的 PCL 膜引导的 rAAV 基因转移介导 sox9 过表达增强人类骨髓抽吸物中的软骨发生分化活性

期刊:Pharmaceutics

影响因子:4.9

doi:10.3390/pharmaceutics12030280

Jagadeesh K Venkatesan, Weikun Meng, Ana Rey-Rico, Gertrud Schmitt, Susanne Speicher-Mentges, Céline Falentin-Daudré, Amélie Leroux, Henning Madry, Véronique Migonney, Magali Cucchiarini

Human

发表日期：2020

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Controlled Release of rAAV Vectors from APMA-Functionalized Contact Lenses for Corneal Gene Therapy

用于角膜基因治疗的 APMA 功能化隐形眼镜中 rAAV 载体的控制释放

期刊:Pharmaceutics

影响因子:4.9

doi:10.3390/pharmaceutics12040335

Fernando Alvarez-Rivera, Ana Rey-Rico, Jagadeesh K Venkatesan, Luis Diaz-Gomez, Magali Cucchiarini, Angel Concheiro, Carmen Alvarez-Lorenzo

信号转导

发表日期：2020

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Effects of rAAV-Mediated sox9 Overexpression on the Biological Activities of Human Osteoarthritic Articular Chondrocytes in Their Intrinsic Three-Dimensional Environment

重组腺相关病毒(rAAV)介导的sox9过表达对人骨关节炎关节软骨细胞在三维环境中生物活性的影响

期刊:Journal of Clinical Medicine

影响因子:3

doi:10.3390/jcm8101637

Oliver Daniels, Janina Frisch, Jagadeesh K Venkatesan, Ana Rey-Rico, Gertrud Schmitt, Magali Cucchiarini

Remodeling of Human Osteochondral Defects via rAAV-Mediated Co-Overexpression of TGF-β and IGF-I from Implanted Human Bone Marrow-Derived Mesenchymal Stromal Cells

通过 rAAV 介导的植入式人骨髓间充质基质细胞 TGF-β 和 IGF-I 共过表达重塑人类骨软骨缺损

期刊:Journal of Clinical Medicine

影响因子:3

doi:10.3390/jcm8091326

Stephanie Morscheid, Jagadeesh Kumar Venkatesan, Ana Rey-Rico, Gertrud Schmitt, Magali Cucchiarini

Therapeutic Effects of rAAV-Mediated Concomittant Gene Transfer and Overexpression of TGF-β and IGF-I on the Chondrogenesis of Human Bone-Marrow-Derived Mesenchymal Stem Cells

重组腺相关病毒 (rAAV) 介导的基因转移及 TGF-β 和 IGF-I 过表达对人骨髓间充质干细胞软骨形成的治疗作用

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms20102591

Stephanie Morscheid, Ana Rey-Rico, Gertrud Schmitt, Henning Madry, Magali Cucchiarini, Jagadeesh Kumar Venkatesan

Improved Chondrogenic Differentiation of rAAV SOX9-Modified Human MSCs Seeded in Fibrin-Polyurethane Scaffolds in a Hydrodynamic Environment

在流体动力环境中，接种于纤维蛋白聚氨酯支架中的 rAAV SOX9 修饰人类 MSCs 的软骨发生分化得到改善

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms19092635

Jagadeesh K Venkatesan, Oliver Gardner, Ana Rey-Rico, David Eglin, Mauro Alini, Martin J Stoddart, Magali Cucchiarini, Henning Madry

表观遗传

发表日期：2018

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rAAV-mediated overexpression of TGF-β via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model

通过聚合物胶束中的载体递送，rAAV 介导的 TGF-β 过度表达可在体外和人类骨软骨缺损模型中刺激人类关节软骨细胞的生物和修复活性

期刊:International Journal of Nanomedicine

影响因子:6.6

doi:10.2147/IJN.S144579

Ana Rey-Rico, Jagadeesh K Venkatesan, Gertrud Schmitt, Angel Concheiro, Henning Madry, Carmen Alvarez-Lorenzo, Magali Cucchiarini

Peripheral blood aspirates overexpressing IGF-I via rAAV gene transfer undergo enhanced chondrogenic differentiation processes

通过 rAAV 基因转移过度表达 IGF-I 的外周血抽吸物经历了增强的软骨发生分化过程

期刊:Journal of Cellular and Molecular Medicine

影响因子:4.3

doi:10.1111/jcmm.13190

Janina Frisch, Patrick Orth, Ana Rey-Rico, Jagadeesh Kumar Venkatesan, Gertrud Schmitt, Henning Madry, Dieter Kohn, Magali Cucchiarini

信号转导

发表日期：2017

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Chondrogenic Differentiation of Human Mesenchymal Stem Cells via SOX9 Delivery in Cationic Niosomes

通过阳离子囊泡中的 SOX9 递送实现人类间充质干细胞的软骨发生分化

Hydrogel-Guided, rAAV-Mediated IGF-I Overexpression Enables Long-Term Cartilage Repair and Protection against Perifocal Osteoarthritis in a Large-Animal Full-Thickness Chondral Defect Model at One Year In Vivo

水凝胶引导、rAAV 介导的 IGF-I 过表达可在体内一年内实现大型动物全层软骨缺损模型的长期软骨修复和对局灶性骨关节炎的预防

Enhanced Chondrogenic Differentiation Activities in Human Bone Marrow Aspirates via sox9 Overexpression Mediated by pNaSS-Grafted PCL Film-Guided rAAV Gene Transfer

通过 pNaSS 嫁接的 PCL 膜引导的 rAAV 基因转移介导 sox9 过表达增强人类骨髓抽吸物中的软骨发生分化活性

Controlled Release of rAAV Vectors from APMA-Functionalized Contact Lenses for Corneal Gene Therapy

用于角膜基因治疗的 APMA 功能化隐形眼镜中 rAAV 载体的控制释放

Effects of rAAV-Mediated sox9 Overexpression on the Biological Activities of Human Osteoarthritic Articular Chondrocytes in Their Intrinsic Three-Dimensional Environment

重组腺相关病毒(rAAV)介导的sox9过表达对人骨关节炎关节软骨细胞在三维环境中生物活性的影响

Remodeling of Human Osteochondral Defects via rAAV-Mediated Co-Overexpression of TGF-β and IGF-I from Implanted Human Bone Marrow-Derived Mesenchymal Stromal Cells

通过 rAAV 介导的植入式人骨髓间充质基质细胞 TGF-β 和 IGF-I 共过表达重塑人类骨软骨缺损

Therapeutic Effects of rAAV-Mediated Concomittant Gene Transfer and Overexpression of TGF-β and IGF-I on the Chondrogenesis of Human Bone-Marrow-Derived Mesenchymal Stem Cells

重组腺相关病毒 (rAAV) 介导的基因转移及 TGF-β 和 IGF-I 过表达对人骨髓间充质干细胞软骨形成的治疗作用

Improved Chondrogenic Differentiation of rAAV SOX9-Modified Human MSCs Seeded in Fibrin-Polyurethane Scaffolds in a Hydrodynamic Environment

在流体动力环境中，接种于纤维蛋白聚氨酯支架中的 rAAV SOX9 修饰人类 MSCs 的软骨发生分化得到改善

rAAV-mediated overexpression of TGF-β via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model

通过聚合物胶束中的载体递送，rAAV 介导的 TGF-β 过度表达可在体外和人类骨软骨缺损模型中刺激人类关节软骨细胞的生物和修复活性

Peripheral blood aspirates overexpressing IGF-I via rAAV gene transfer undergo enhanced chondrogenic differentiation processes

通过 rAAV 基因转移过度表达 IGF-I 的外周血抽吸物经历了增强的软骨发生分化过程