日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia: A Randomized Clinical Trial

万古霉素或达托霉素联合或不联合抗葡萄球菌β-内酰胺类药物对MRSA菌血症患者死亡率、菌血症、复发或治疗失败的影响:一项随机临床试验

Tong, Steven Y C; Lye, David C; Yahav, Dafna; Sud, Archana; Robinson, J Owen; Nelson, Jane; Archuleta, Sophia; Roberts, Matthew A; Cass, Alan; Paterson, David L; Foo, Hong; Paul, Mical; Guy, Stephen D; Tramontana, Adrian R; Walls, Genevieve B; McBride, Stephen; Bak, Narin; Ghosh, Niladri; Rogers, Benjamin A; Ralph, Anna P; Davies, Jane; Ferguson, Patricia E; Dotel, Ravindra; McKew, Genevieve L; Gray, Timothy J; Holmes, Natasha E; Smith, Simon; Warner, Morgyn S; Kalimuddin, Shirin; Young, Barnaby E; Runnegar, Naomi; Andresen, David N; Anagnostou, Nicholas A; Johnson, Sandra A; Chatfield, Mark D; Cheng, Allen C; Fowler, Vance G Jr; Howden, Benjamin P; Meagher, Niamh; Price, David J; van Hal, Sebastiaan J; O'Sullivan, Matthew V N; Davis, Joshua S

Assessment of novel vaccination regimens using viral vectored liver stage malaria vaccines encoding ME-TRAP

利用编码 ME-TRAP 的病毒载体肝期疟疾疫苗评估新型疫苗接种方案

Bliss, Carly M; Bowyer, Georgina; Anagnostou, Nicholas A; Havelock, Tom; Snudden, Claudia M; Davies, Huw; de Cassan, Simone C; Grobbelaar, Amy; Lawrie, Alison M; Venkatraman, Navin; Poulton, Ian D; Roberts, Rachel; Mange, Pooja B; Choudhary, Prateek; Faust, Saul N; Colloca, Stefano; Gilbert, Sarah C; Nicosia, Alfredo; Hill, Adrian V S; Ewer, Katie J

First field efficacy trial of the ChAd63 MVA ME-TRAP vectored malaria vaccine candidate in 5-17 months old infants and children

ChAd63 MVA ME-TRAP载体疟疾疫苗候选药物在5-17个月大的婴幼儿中首次开展现场疗效试验

Tiono, Alfred B; Nébié, Issa; Anagnostou, Nicholas; Coulibaly, Aboubacar S; Bowyer, Georgina; Lam, Erika; Bougouma, Edith C; Ouedraogo, Alphonse; Yaro, Jean Baptist B; Barry, Aïssata; Roberts, Rachel; Rampling, Tommy; Bliss, Carly; Hodgson, Susanne; Lawrie, Alison; Ouedraogo, Amidou; Imoukhuede, Egeruan Babatunde; Ewer, Katie J; Viebig, Nicola K; Diarra, Amidou; Leroy, Odile; Bejon, Philip; Hill, Adrian V S; Sirima, Sodiomon B

Safety and Immunogenicity of ChAd63 and MVA ME-TRAP in West African Children and Infants

ChAd63 和 MVA ME-TRAP 在西非儿童和婴儿中的安全性和免疫原性

Afolabi, Muhammed O; Tiono, Alfred B; Adetifa, Uche J; Yaro, Jean Baptiste; Drammeh, Abdoulie; Nébié, Issa; Bliss, Carly; Hodgson, Susanne H; Anagnostou, Nicholas A; Sanou, Guillaume S; Jagne, Ya Jankey; Ouedraogo, Oumarou; Tamara, Casimir; Ouedraogo, Nicolas; Ouedraogo, Mirielle; Njie-Jobe, Jainaba; Diarra, Amidou; Duncan, Christopher Ja; Cortese, Riccardo; Nicosia, Alfredo; Roberts, Rachel; Viebig, Nicola K; Leroy, Odile; Lawrie, Alison M; Flanagan, Katie L; Kampman, Beate; Bejon, Philip; Imoukhuede, Egeruan B; Ewer, Katie J; Hill, Adrian Vs; Bojang, Kalifa; Sirima, Sodiomon B

Safety, Immunogenicity and Efficacy of Prime-Boost Vaccination with ChAd63 and MVA Encoding ME-TRAP against Plasmodium falciparum Infection in Adults in Senegal

在塞内加尔成人中,使用编码 ME-TRAP 的 ChAd63 和 MVA 进行初免-加强免疫接种预防恶性疟原虫感染的安全性、免疫原性和有效性

Mensah, Victorine A; Gueye, Aly; Ndiaye, Magatte; Edwards, Nick J; Wright, Danny; Anagnostou, Nicholas A; Syll, Massamba; Ndaw, Amy; Abiola, Annie; Bliss, Carly; Gomis, Jules-François; Petersen, Ines; Ogwang, Caroline; Dieye, Tandakha; Viebig, Nicola K; Lawrie, Alison M; Roberts, Rachel; Nicosia, Alfredo; Faye, Babacar; Gaye, Oumar; Leroy, Odile; Imoukhuede, Egeruan B; Ewer, Katie J; Bejon, Philip; Hill, Adrian V S; Cisse, Badara

Evaluation of the efficacy of ChAd63-MVA vectored vaccines expressing circumsporozoite protein and ME-TRAP against controlled human malaria infection in malaria-naive individuals

评估表达环子孢子蛋白和ME-TRAP的ChAd63-MVA载体疫苗对未感染过疟疾的个体控制性人类疟疾感染的疗效

Hodgson, Susanne H; Ewer, Katie J; Bliss, Carly M; Edwards, Nick J; Rampling, Thomas; Anagnostou, Nicholas A; de Barra, Eoghan; Havelock, Tom; Bowyer, Georgina; Poulton, Ian D; de Cassan, Simone; Longley, Rhea; Illingworth, Joseph J; Douglas, Alexander D; Mange, Pooja B; Collins, Katharine A; Roberts, Rachel; Gerry, Stephen; Berrie, Eleanor; Moyle, Sarah; Colloca, Stefano; Cortese, Riccardo; Sinden, Robert E; Gilbert, Sarah C; Bejon, Philip; Lawrie, Alison M; Nicosia, Alfredo; Faust, Saul N; Hill, Adrian V S

Increased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studies

在受控的人类疟疾感染研究中,增加样本量和使用定量逆转录PCR可以提高对肝脏到血液接种量的预测准确性。

Hodgson, Susanne H; Douglas, Alexander D; Edwards, Nick J; Kimani, Domtila; Elias, Sean C; Chang, Ming; Daza, Glenda; Seilie, Annette M; Magiri, Charles; Muia, Alfred; Juma, Elizabeth A; Cole, Andrew O; Rampling, Thomas W; Anagnostou, Nicholas A; Gilbert, Sarah C; Hoffman, Stephen L; Draper, Simon J; Bejon, Philip; Ogutu, Bernhards; Marsh, Kevin; Hill, Adrian V S; Murphy, Sean C

Translating the immunogenicity of prime-boost immunization with ChAd63 and MVA ME-TRAP from malaria naive to malaria-endemic populations

将 ChAd63 和 MVA ME-TRAP 初免-加强免疫的免疫原性从疟疾未感染人群转化到疟疾流行人群

Kimani, Domtila; Jagne, Ya Jankey; Cox, Momodou; Kimani, Eva; Bliss, Carly M; Gitau, Evelyn; Ogwang, Caroline; Afolabi, Muhammed O; Bowyer, Georgina; Collins, Katharine A; Edwards, Nick; Hodgson, Susanne H; Duncan, Christopher J A; Spencer, Alexandra J; Knight, Miguel G; Drammeh, Abdoulie; Anagnostou, Nicholas A; Berrie, Eleanor; Moyle, Sarah; Gilbert, Sarah C; Soipei, Peninah; Okebe, Joseph; Colloca, Stefano; Cortese, Riccardo; Viebig, Nicola K; Roberts, Rachel; Lawrie, Alison M; Nicosia, Alfredo; Imoukhuede, Egeruan B; Bejon, Philip; Chilengi, Roma; Bojang, Kalifa; Flanagan, Katie L; Hill, Adrian V S; Urban, Britta C; Ewer, Katie J

Safety and immunogenicity of heterologous prime-boost immunisation with Plasmodium falciparum malaria candidate vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in healthy Gambian and Kenyan adults

在健康的冈比亚和肯尼亚成年人中,使用恶性疟原虫候选疫苗 ChAd63 ME-TRAP 和 MVA ME-TRAP 进行异源初免-加强免疫的安全性和免疫原性

Ogwang, Caroline; Afolabi, Muhammed; Kimani, Domtila; Jagne, Ya Jankey; Sheehy, Susanne H; Bliss, Carly M; Duncan, Christopher J A; Collins, Katharine A; Garcia Knight, Miguel A; Kimani, Eva; Anagnostou, Nicholas A; Berrie, Eleanor; Moyle, Sarah; Gilbert, Sarah C; Spencer, Alexandra J; Soipei, Peninah; Mueller, Jenny; Okebe, Joseph; Colloca, Stefano; Cortese, Riccardo; Viebig, Nicola K; Roberts, Rachel; Gantlett, Katherine; Lawrie, Alison M; Nicosia, Alfredo; Imoukhuede, Egeruan B; Bejon, Philip; Urban, Britta C; Flanagan, Katie L; Ewer, Katie J; Chilengi, Roma; Hill, Adrian V S; Bojang, Kalifa

Vaccine vectors derived from a large collection of simian adenoviruses induce potent cellular immunity across multiple species.

源自大量猿猴腺病毒的疫苗载体可在多种物种中诱导强大的细胞免疫

Colloca Stefano, Barnes Eleanor, Folgori Antonella, Ammendola Virginia, Capone Stefania, Cirillo Agostino, Siani Loredana, Naddeo Mariarosaria, Grazioli Fabiana, Esposito Maria Luisa, Ambrosio Maria, Sparacino Angela, Bartiromo Marta, Meola Annalisa, Smith Kira, Kurioka Ayako, O'Hara Geraldine A, Ewer Katie J, Anagnostou Nicholas, Bliss Carly, Hill Adrian V S, Traboni Cinzia, Klenerman Paul, Cortese Riccardo, Nicosia Alfredo