日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Microtubule-Targeting Combined with HDAC Inhibition Is a Novel Therapeutic Strategy for Diffuse Intrinsic Pontine Gliomas

微管靶向治疗与 HDAC 抑制相结合是治疗弥漫性内在性脑桥胶质瘤的新策略

Anahid Ehteda #, Aaminah Khan #, Gayathiri Rajakumar, Anne S Vanniasinghe, Anjana Gopalakrishnan, Jie Liu, Maria Tsoli #, David S Ziegler #

Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas

弥漫性内在性脑桥胶质瘤中多胺合成和摄取的双重靶向

Aaminah Khan, Laura D Gamble, Dannielle H Upton, Caitlin Ung, Denise M T Yu, Anahid Ehteda, Ruby Pandher, Chelsea Mayoh, Steven Hébert, Nada Jabado, Claudia L Kleinman, Mark R Burns, Murray D Norris, Michelle Haber, Maria Tsoli #, David S Ziegler #

Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma

Curaxin CBL0137 和组蛋白去乙酰化酶抑制剂帕比司他双重靶向染色质稳定性,在神经母细胞瘤的临床前研究中显示出显著疗效。

Lin Xiao # ,Klaartje Somers # ,Jayne Murray ,Ruby Pandher ,Mawar Karsa ,Emma Ronca ,Angelika Bongers ,Rachael Terry ,Anahid Ehteda ,Laura D Gamble ,Natalia Issaeva ,Katerina I Leonova ,Aisling O'Connor ,Chelsea Mayoh ,Pooja Venkat ,Hazel Quek ,Jennifer Brand ,Frances K Kusuma ,Jessica A Pettitt ,Erin Mosmann ,Adam Kearns ,Georgina Eden ,Stephanie Alfred ,Sophie Allan ,Lei Zhai ,Alvin Kamili ,Andrew J Gifford ,Daniel R Carter ,Michelle J Henderson ,Jamie I Fletcher ,Glenn Marshall ,Ricky W Johnstone ,Anthony J Cesare ,David S Ziegler ,Andrei V Gudkov ,Katerina V Gurova ,Murray D Norris # ,Michelle Haber #

Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG

通过 FACT 复合物和组蛋白去乙酰化酶双重靶向表观基因组是治疗 DIPG 的有效策略

Anahid Ehteda, Sandy Simon, Laura Franshaw, Federico M Giorgi, Jie Liu, Swapna Joshi, Jourdin R C Rouaen, Chi Nam Ignatius Pang, Ruby Pandher, Chelsea Mayoh, Yujie Tang, Aaminah Khan, Caitlin Ung, Ornella Tolhurst, Anne Kankean, Elisha Hayden, Rebecca Lehmann, Sylvie Shen, Anjana Gopalakrishnan, Pet

Doxorubicin-Loaded Gold Nanoarchitectures as a Therapeutic Strategy against Diffuse Intrinsic Pontine Glioma

载阿霉素的金纳米结构作为治疗弥漫性内在性脑桥胶质瘤的治疗策略

Caitlin Ung, Maria Tsoli, Jie Liu, Domenico Cassano, Salvador Pocoví-Martínez, Dannielle H Upton, Anahid Ehteda, Friederike M Mansfeld, Timothy W Failes, Annafranca Farfalla, Christopher Katsinas, Maria Kavallaris, Greg M Arndt, Orazio Vittorio, Giuseppe Cirillo, Valerio Voliani, David S Ziegler

Dual targeting of mitochondrial function and mTOR pathway as a therapeutic strategy for diffuse intrinsic pontine glioma

线粒体功能和 mTOR 通路双重靶向作为弥漫性内在性脑桥胶质瘤的治疗策略

Maria Tsoli, Jie Liu, Laura Franshaw, Han Shen, Cecilia Cheng, MoonSun Jung, Swapna Joshi, Anahid Ehteda, Aaminah Khan, Angel Montero-Carcabosso, Pierre J Dilda, Philip Hogg, David S Ziegler

Pre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models

帕比司他用于异种移植和基因工程小鼠弥漫性内在性脑桥胶质瘤模型的临床前研究

Tammy Hennika, Guo Hu, Nagore G Olaciregui, Kelly L Barton, Anahid Ehteda, Arjanna Chitranjan, Cecilia Chang, Andrew J Gifford, Maria Tsoli, David S Ziegler, Angel M Carcaboso, Oren J Becher

The expression of the Sprouty 1 protein inversely correlates with growth, proliferation, migration and invasion of ovarian cancer cells

Sprouty 1 蛋白的表达与卵巢癌细胞的生长、增殖、迁移和侵袭呈负相关

Samar Masoumi-Moghaddam, Afshin Amini, Anahid Ehteda, Ai-Qun Wei, David Lawson Morris

Combination of albendazole and 2-methoxyestradiol significantly improves the survival of HCT-116 tumor-bearing nude mice

阿苯达唑与2-甲氧基雌二醇联合用药显著提高HCT-116荷瘤裸鼠的生存率

Anahid Ehteda, Peter Galettis, Krishna Pillai, David L Morris