日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A highly potent and broadly accessible bispecific nanobody for the treatment of ebola virus infections

一种高效且易于获取的双特异性纳米抗体,可用于治疗埃博拉病毒感染

Bu, Fan; Ye, Gang; Morsheimer, Kimberly; Turner-Hubbard, Hailey; Eaton, Brett; Anantpadma, Manu; Bheemanapally, Khaggeswar; Tan, Chalet; Davey, Robert; Li, Fang

Replicon-based genome-wide CRISPR knockout screening for the identification of host factors involved in viral replication.

基于复制子的全基因组 CRISPR 敲除筛选,用于鉴定参与病毒复制的宿主因子。

Cheng Karen W, Bhave Madhura, Markhard Andrew L, Peng Duo, Bhatt Karan D, Travisano Katherine A, Medicielo Josette V, Anaya Astrid, Lembirik Sanae, Njoya Leila, Anantpadma Manu, Kuhn Jens H, Puschnik Andreas S, Kistler Amy L

Guardians at the Gate: Optimization of Small Molecule Entry Inhibitors of Ebola and Marburg Viruses.

守门人:埃博拉病毒和马尔堡病毒小分子进入抑制剂的优化

Argade Malaika D, Achi Jazmin Galván, Bott Ryan, Morsheimer Kimberly M, Owen Callum D, Zielinski Christian A, Gaisin Arsen M, Alvarez Mario, Moore Terry W, Bu Fan, Li Fang, Cameron Michael, Anantpadma Manu, Davey Robert A, Peet Norton P, Rong Lijun, Gaisina Irina N

Discovery of Nanosota-EB1 and -EB2 as Novel Nanobody Inhibitors Against Ebola Virus Infection

发现 Nanosota-EB1 和 -EB2 作为新型纳米抗体抑制剂对抗埃博拉病毒感染

Bu, Fan; Ye, Gang; Morsheimer, Kimberly; Mendoza, Alise; Turner-Hubbard, Hailey; Herbst, Morgan; Spiller, Benjamin; Wadzinski, Brian E; Eaton, Brett; Anantpadma, Manu; Yang, Ge; Liu, Bin; Davey, Robert; Li, Fang

Identification of potent inhibitors of SARS-CoV-2 infection by combined pharmacological evaluation and cellular network prioritization

通过药理学评价和细胞网络优先排序相结合的方式鉴定 SARS-CoV-2 感染的有效抑制剂

J J Patten, Patrick T Keiser, Deisy Morselli-Gysi, Giulia Menichetti, Hiroyuki Mori, Callie J Donahue, Xiao Gan, Italo do Valle, Kathleen Geoghegan-Barek, Manu Anantpadma, RuthMabel Boytz, Jacob L Berrigan, Sarah H Stubbs, Tess Ayazika, Colin O'Leary, Sallieu Jalloh, Florence Wagner, Seyoum Ayehunie

Evaluation of Phenol-Substituted Diphyllin Derivatives as Selective Antagonists for Ebola Virus Entry

苯酚取代的二酚衍生物作为埃博拉病毒入侵选择性拮抗剂的评估

Caroline B Plescia, Aaron R Lindstrom, Maritza V Quintero, Patrick Keiser, Manu Anantpadma, Robert Davey, Robert V Stahelin, V Jo Davisson

Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection

非典型脯氨酸-酪氨酸与多种宿主蛋白的相互作用调节埃博拉病毒感染

Jyoti Batra, Hiroyuki Mori, Gabriel I Small, Manu Anantpadma, Olena Shtanko, Nawneet Mishra, Mengru Zhang, Dandan Liu, Caroline G Williams, Nadine Biedenkopf, Stephan Becker, Michael L Gross, Daisy W Leung, Robert A Davey, Gaya K Amarasinghe, Nevan J Krogan, Christopher F Basler

Automation of Infectious Focus Assay for Determination of Filovirus Titers and Direct Comparison to Plaque and TCID50 Assays

感染灶检测自动化,用于测定丝状病毒滴度并与斑块和 TCID50 检测直接比较

Patrick T Keiser, Manu Anantpadma, Hilary Staples, Ricardo Carrion, Robert A Davey

Pyronaridine tetraphosphate efficacy against Ebola virus infection in guinea pig

吡咯萘啶四磷酸盐对豚鼠埃博拉病毒感染的疗效

Thomas R Lane, Christopher Massey, Jason E Comer, Alexander N Freiberg, Huanying Zhou, Julie Dyall, Michael R Holbrook, Manu Anantpadma, Robert A Davey, Peter B Madrid, Sean Ekins

The Natural Product Eugenol Is an Inhibitor of the Ebola Virus In Vitro

天然产物丁香酚在体外可抑制埃博拉病毒

Lane, Thomas; Anantpadma, Manu; Freundlich, Joel S; Davey, Robert A; Madrid, Peter B; Ekins, Sean