日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Efficacy and Safety of Adagrasib plus Cetuximab in Patients with KRASG12C-Mutated Metastatic Colorectal Cancer

阿达格拉西布联合西妥昔单抗治疗KRASG12C突变转移性结直肠癌患者的疗效和安全性

Yaeger, Rona; Uboha, Nataliya V; Pelster, Meredith S; Bekaii-Saab, Tanios S; Barve, Minal; Saltzman, Joel; Sabari, Joshua K; Peguero, Julio A; Paulson, Andrew Scott; Jänne, Pasi A; Cruz-Correa, Marcia; Anderes, Kenna; Velastegui, Karen; Yan, Xiaohong; Der-Torossian, Hirak; Klempner, Samuel J; Kopetz, Scott E

Early Changes in Circulating Cell-Free KRAS G12C Predict Response to Adagrasib in KRAS Mutant Non-Small Cell Lung Cancer Patients

循环游离KRAS G12C的早期变化可预测KRAS突变型非小细胞肺癌患者对阿达格拉西布的反应

Paweletz, Cloud P; Heavey, Grace A; Kuang, Yanan; Durlacher, Emily; Kheoh, Thian; Chao, Richard C; Spira, Alexander I; Leventakos, Konstantinos; Johnson, Melissa L; Ou, Sai-Hong Ignatius; Riely, Gregory J; Anderes, Kenna; Yang, Wenjing; Christensen, James G; Jänne, Pasi A

Hospitalization Outcomes Among Patients With COVID-19 Undergoing Remote Monitoring

接受远程监测的新冠肺炎患者的住院结果

Crotty, Bradley H; Dong, Yilu; Laud, Purushottam; Hanson, Ryan J; Gershkowitz, Bradley; Penlesky, Annie C; Shah, Neemit; Anderes, Michael; Green, Erin; Fickel, Karen; Singh, Siddhartha; Somai, Melek M

The role of γ-secretase activating protein (GSAP) and imatinib in the regulation of γ-secretase activity and amyloid-β generation

γ-分泌酶活化蛋白(GSAP)及伊马替尼在调节γ-分泌酶活性和淀粉样β蛋白生成中的作用

Ishrut Hussain, Julien Fabrègue, Laurence Anderes, Solenne Ousson, Frédéric Borlat, Valérie Eligert, Sébastien Berger, Mitko Dimitrov, Jean-René Alattia, Patrick C Fraering, Dirk Beher

Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.

抑制 RNA 聚合酶 I 作为促进 p53 癌症特异性激活的治疗策略

Bywater Megan J, Poortinga Gretchen, Sanij Elaine, Hein Nadine, Peck Abigail, Cullinane Carleen, Wall Meaghan, Cluse Leonie, Drygin Denis, Anderes Kenna, Huser Nanni, Proffitt Chris, Bliesath Joshua, Haddach Mustapha, Schwaebe Michael K, Ryckman David M, Rice William G, Schmitt Clemens, Lowe Scott W, Johnstone Ricky W, Pearson Richard B, McArthur Grant A, Hannan Ross D

CK2 inhibitor CX-4945 suppresses DNA repair response triggered by DNA-targeted anticancer drugs and augments efficacy: mechanistic rationale for drug combination therapy

CK2 抑制剂 CX-4945 抑制 DNA 靶向抗癌药物引发的 DNA 修复反应并增强疗效:药物联合治疗的机制原理

Adam Siddiqui-Jain, Joshua Bliesath, Diwata Macalino, Mayuko Omori, Nanni Huser, Nicole Streiner, Caroline B Ho, Kenna Anderes, Chris Proffitt, Sean E O'Brien, John K C Lim, Daniel D Von Hoff, David M Ryckman, William G Rice, Denis Drygin

Identification and validation of inhibitor-responsive kinase substrates using a new paradigm to measure kinase-specific protein phosphorylation index

使用新范式测量激酶特异性蛋白磷酸化指数来鉴定和验证抑制剂反应性激酶底物

Xiang Li, Varsha Rao, Jin Jin, Bin Guan, Kenna L Anderes, Charles J Bieberich

PF-00477736 mediates checkpoint kinase 1 signaling pathway and potentiates docetaxel-induced efficacy in xenografts

PF-00477736 介导检查点激酶 1 信号通路并增强多西他赛在异种移植中诱导的疗效

Cathy Zhang, Zhengming Yan, Cory L Painter, Qin Zhang, Enhong Chen, Maria E Arango, Kyle Kuszpit, Kenneth Zasadny, Max Hallin, Jill Hallin, Anthony Wong, Dana Buckman, Guizhen Sun, Ming Qiu, Kenna Anderes, James G Christensen

ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: potential basis for the UV protective effects of caffeine

ATR-Chk1 通路抑制促进原代人类角质形成细胞在紫外线治疗后凋亡:咖啡因紫外线防护作用的潜在基础

Timothy P Heffernan, Masaoki Kawasumi, Alessandra Blasina, Kenna Anderes, Allan H Conney, Paul Nghiem

PCR detection of granulocytic ehrlichiae in Ixodes ricinus ticks and wild small mammals in western Switzerland

在瑞士西部,利用PCR技术检测蓖麻硬蜱和野生小型哺乳动物体内的粒细胞埃里希氏体

Liz, J S; Anderes, L; Sumner, J W; Massung, R F; Gern, L; Rutti, B; Brossard, M