ATOR-4066, a Bispecific Antibody Targeting CD40 and CEACAM5, Induces Strong Myeloid and T Cell-Dependent Tumor Immunity and Synergizes with PD-1 Blockade
ATOR-4066 是一种靶向 CD40 和 CEACAM5 的双特异性抗体，可诱导强烈的髓系和 T 细胞依赖性肿瘤免疫，并与 PD-1 阻断剂产生协同作用。
期刊:Cancer Immunology Research
影响因子:8.1
doi:10.1158/2326-6066.CIR-25-0075.
Hampus Andersson ,Ida Uddbäck ,Tova Hermodsson ,Mona Celander ,Amulya Krishna Shetty ,Lill Ljung ,Anneli Nilsson ,Anette Sundstedt ,Laura von Schantz ,Laura A Varas ,Mattias Levin ,Anna Säll ,Dietmar Weilguny ,Kim Jansson ,Sara Fritzell ,Karin Hägerbrand ,Malin Lindstedt # ,Peter Ellmark #
免疫/内分泌
肿瘤
T细胞
CD4
CD40
CEACAM5
PD-1
肿瘤免疫
