日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Evaluation of an in vivo pulmonary aspergillosis model for triazole susceptibility breakpoint development

评估体内肺曲霉病模型对三唑类药物敏感性断点的建立

Lepak, Alex; Bhavnani, Sujata M; Castanheira, Mariana; Rubino, Christopher M; Hammel, Jeffrey P; Safir, M Courtney; Massey, Justin; Hartman, William; Ambrose, Paul; Andes, David

Pharmacodynamic evaluation of BRII-693, a next-generation synthetic macrocyclic peptide antibiotic, in the neutropenic mouse thigh and lung infection models against gram-negative pathogens

在嗜中性粒细胞减少的小鼠大腿和肺部感染模型中,对新一代合成大环肽抗生素 BRII-693 进行药效学评价,以对抗革兰氏阴性病原体。

Lepak, Alexander J; Zhu, Yali; Andes, David R

Characterizing extracellular vesicles of human fungal pathogens

人类真菌病原体细胞外囊泡的特征分析

Rodrigues, Marcio L; Janbon, Guilhem; O'Connell, Richard J; Chu, Thi-Thu-Huyen; May, Robin C; Jin, Hailing; Reis, Flavia C G; Alves, Lysangela R; Puccia, Rosana; Fill, Taicia P; Rizzo, Juliana; Zamith-Miranda, Daniel; Miranda, Kildare; Gonçalves, Teresa; Ene, Iuliana V; Kabani, Mehdi; Anderson, Marilyn; Gow, Neil A R; Andes, David R; Casadevall, Arturo; Nosanchuk, Joshua D; Nimrichter, Leonardo

Ume6 protein complexes connect morphogenesis, adherence and hypoxic genes to shape Candida albicans biofilm architecture.

Ume6 蛋白复合物连接形态发生、粘附和缺氧基因,从而塑造白色念珠菌生物膜的结构

Do Eunsoo, McManus C Joel, Zarnowski Robert, Huang Manning Y, Goerlich Katharina, Andes David R, Mitchell Aaron P

Structure-guided optimization of small molecules targeting Yck2 as a strategy to combat Candida albicans

以Yck2为靶点的小分子结构导向优化作为对抗白色念珠菌的策略

Puumala, Emily; Nandakumar, Meganathan; Yiu, Bonnie; Stogios, Peter J; Strickland, Benjamin G; Zarnowski, Robert; Wang, Xiaoyu; Williams, Noelle S; Savchenko, Alexei; Andes, David R; Robbins, Nicole; Whitesell, Luke; Willson, Timothy M; Cowen, Leah E

A humanized antibody against mucormycosis targets angioinvasion and augments the host immune response.

针对毛霉菌病的人源化抗体靶向血管侵袭并增强宿主免疫反应

Gu Yiyou, Singh Shakti, Alqarihi Abdullah, Alkhazraji Sondus, Gebremariam Teclegiorgis, Youssef Eman G, Liu Hong, Fan Xiaomin, Jiang Wen-Rong, Andes David, Cochrane Terrence R, Schwartz Julie A, Filler Scott G, Uppuluri Priya, Ibrahim Ashraf S

Plasma Microbial Cell-free DNA Metagenomic Sequencing for Diagnosis of Invasive Fungal Diseases Among High-risk Outpatient and Inpatient Immunocompromised Hosts

血浆微生物游离DNA宏基因组测序在免疫功能低下高危门诊和住院患者侵袭性真菌病诊断中的应用

Sim, Beatrice Z; Mah, Jordan K; Heldman, Madeleine R; Stanly, Kelly L; Hanson, Kimberly E; Caliendo, Angela M; Andes, David; Ostrosky-Zeichner, Luis; Wingard, John R; Alexander, Barbara D

The antifungal mechanism of EntV-derived peptides is associated with a reduction in extracellular vesicle release

EntV衍生肽的抗真菌机制与细胞外囊泡释放减少有关

Buda De Cesare, Giuseppe; Cruz, Melissa R; Cristy, Shane A; Vega, Luis A; Zarnowski, Robert; Zito, Antonino; Guha, Shantanu; Andes, David R; Garsin, Danielle A; Lorenz, Michael C

Dual function of Candida auris mannosyltransferase, MNT5, in biofilm community protection from antifungal therapy and the host

耳念珠菌甘露糖基转移酶MNT5在生物膜群落抵御抗真菌治疗和宿主损伤中的双重作用

Zarnowski, Robert; Horton, Mark V; Johnson, Chad J; Vang, Por Choua; Uram, Jeremy; Fernando, Liyanage Devthilini Pasasum; Vlach, Jiri; Heiss, Christian; Azadi, Parastoo; Nett, Jeniel E; Andes, David R

Genetic interaction analysis of Candida glabrata transcription factors CST6 and UPC2A in the regulation of respiration and fluconazole susceptibility

念珠菌转录因子CST6和UPC2A在呼吸调控和氟康唑敏感性中的遗传相互作用分析

Ollinger, Tomye L; Zarnowski, Robert; Parker, Josie E; Kelly, Steven L; Andes, David R; Stamnes, Mark A; Krysan, Damian J