日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacodynamic evaluation of BRII-693, a next-generation synthetic macrocyclic peptide antibiotic, in the neutropenic mouse thigh and lung infection models against gram-negative pathogens

在嗜中性粒细胞减少的小鼠大腿和肺部感染模型中,对新一代合成大环肽抗生素 BRII-693 进行药效学评价,以对抗革兰氏阴性病原体。

Lepak, Alexander J; Zhu, Yali; Andes, David R

Characterizing extracellular vesicles of human fungal pathogens

人类真菌病原体细胞外囊泡的特征分析

Rodrigues, Marcio L; Janbon, Guilhem; O'Connell, Richard J; Chu, Thi-Thu-Huyen; May, Robin C; Jin, Hailing; Reis, Flavia C G; Alves, Lysangela R; Puccia, Rosana; Fill, Taicia P; Rizzo, Juliana; Zamith-Miranda, Daniel; Miranda, Kildare; Gonçalves, Teresa; Ene, Iuliana V; Kabani, Mehdi; Anderson, Marilyn; Gow, Neil A R; Andes, David R; Casadevall, Arturo; Nosanchuk, Joshua D; Nimrichter, Leonardo

Ume6 protein complexes connect morphogenesis, adherence and hypoxic genes to shape Candida albicans biofilm architecture.

Ume6 蛋白复合物连接形态发生、粘附和缺氧基因,从而塑造白色念珠菌生物膜的结构

Do Eunsoo, McManus C Joel, Zarnowski Robert, Huang Manning Y, Goerlich Katharina, Andes David R, Mitchell Aaron P

Structure-guided optimization of small molecules targeting Yck2 as a strategy to combat Candida albicans

以Yck2为靶点的小分子结构导向优化作为对抗白色念珠菌的策略

Puumala, Emily; Nandakumar, Meganathan; Yiu, Bonnie; Stogios, Peter J; Strickland, Benjamin G; Zarnowski, Robert; Wang, Xiaoyu; Williams, Noelle S; Savchenko, Alexei; Andes, David R; Robbins, Nicole; Whitesell, Luke; Willson, Timothy M; Cowen, Leah E

The antifungal mechanism of EntV-derived peptides is associated with a reduction in extracellular vesicle release

EntV衍生肽的抗真菌机制与细胞外囊泡释放减少有关

Buda De Cesare, Giuseppe; Cruz, Melissa R; Cristy, Shane A; Vega, Luis A; Zarnowski, Robert; Zito, Antonino; Guha, Shantanu; Andes, David R; Garsin, Danielle A; Lorenz, Michael C

Dual function of Candida auris mannosyltransferase, MNT5, in biofilm community protection from antifungal therapy and the host

耳念珠菌甘露糖基转移酶MNT5在生物膜群落抵御抗真菌治疗和宿主损伤中的双重作用

Zarnowski, Robert; Horton, Mark V; Johnson, Chad J; Vang, Por Choua; Uram, Jeremy; Fernando, Liyanage Devthilini Pasasum; Vlach, Jiri; Heiss, Christian; Azadi, Parastoo; Nett, Jeniel E; Andes, David R

Genetic interaction analysis of Candida glabrata transcription factors CST6 and UPC2A in the regulation of respiration and fluconazole susceptibility

念珠菌转录因子CST6和UPC2A在呼吸调控和氟康唑敏感性中的遗传相互作用分析

Ollinger, Tomye L; Zarnowski, Robert; Parker, Josie E; Kelly, Steven L; Andes, David R; Stamnes, Mark A; Krysan, Damian J

Evaluation of Aminoglycoside Dosing Regimens Adjusted for Renal Function and In Vitro Susceptibility Test Interpretive Criteria for Enterobacterales and Pseudomonas aeruginosa: Brief Summary

氨基糖苷类药物剂量方案评估(根据肾功能调整)及肠杆菌科细菌和铜绿假单胞菌体外药敏试验判读标准:简要概述

Bhavnani, Sujata M; Hammel, Jeffrey P; Onufrak, Nikolas J; Pogue, Jason M; Jones, Ronald N; Sader, Helio S; Drusano, George L; Bradley, John S; Andes, David R; Craig, William A; Ambrose, Paul G

Evaluation of Aminoglycoside Dosing Regimens Adjusted for Renal Function and In Vitro Susceptibility Test Interpretive Criteria for Enterobacterales and Pseudomonas aeruginosa

评估根据肾功能调整的氨基糖苷类药物给药方案以及肠杆菌科和铜绿假单胞菌体外药敏试验判读标准

Bhavnani, Sujata M; Hammel, Jeffrey P; Onufrak, Nikolas J; Pogue, Jason M; Jones, Ronald N; Sader, Helio S; Drusano, George L; Bradley, John S; Andes, David R; Craig, William A; Ambrose, Paul G

Candida albicans biofilm extracellular vesicles deliver candidalysin to epithelial cell membranes and induce host cell responses

白色念珠菌生物膜胞外囊泡将念珠菌溶素递送至上皮细胞膜并诱导宿主细胞反应。

Lee, Sejeong; Tsavou, Antzela; Zarnowski, Robert; Pforte, Rita; Allert, Stefanie; Krüger, Thomas; Kniemeyer, Olaf; Brakhage, Axel A; Bui, Tam T T; Andes, David R; Richardson, Jonathan P; Hube, Bernhard; Naglik, Julian R