日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection

肝脏免疫调节器在慢性乙型肝炎病毒感染中调节CD8 T细胞免疫。

Miriam Bosch # ,Nina Kallin # ,Sainitin Donakonda ,Jitao David Zhang ,Hannah Wintersteller ,Silke Hegenbarth ,Kathrin Heim ,Carlos Ramirez ,Anna Fürst ,Elias Isaac Lattouf ,Martin Feuerherd ,Sutirtha Chattopadhyay ,Nadine Kumpesa ,Vera Griesser ,Jean-Christophe Hoflack ,Juliane Siebourg-Polster ,Carolin Mogler ,Leo Swadling ,Laura J Pallett ,Philippa Meiser ,Katrin Manske ,Gustavo P de Almeida ,Anna D Kosinska ,Ioana Sandu ,Annika Schneider ,Vincent Steinbacher ,Yan Teng ,Julia Schnabel ,Fabian Theis ,Adam J Gehring ,Andre Boonstra ,Harry L A Janssen ,Michiel Vandenbosch ,Eva Cuypers ,Rupert Öllinger ,Thomas Engleitner ,Roland Rad ,Katja Steiger ,Annette Oxenius ,Wan-Lin Lo ,Victoria Klepsch ,Gottfried Baier ,Bernhard Holzmann ,Mala K Maini ,Ron Heeren ,Peter J Murray ,Robert Thimme ,Carl Herrmann ,Ulrike Protzer ,Jan P Böttcher ,Dietmar Zehn ,Dirk Wohlleber ,Georg M Lauer ,Maike Hofmann ,Souphalone Luangsay ,Percy A Knolle

Association of HBsAg levels with differential gene expression in NK, CD8 T, and memory B cells in treated patients with chronic HBV

接受治疗的慢性 HBV 患者中 HBsAg 水平与 NK、CD8 T 和记忆 B 细胞中差异基因表达的关联

Boris J B Beudeker, Zgjim Osmani, Gertine W van Oord, Zwier M A Groothuismink, Robert J de Knegt, Remco M Hoogenboezem, Eric M J Bindels, Harmen J G van de Werken, Andre Boonstra

Treatment induced clearance of hepatitis E viruses by interferon-lambda in liver-humanized mice

干扰素-λ 在肝人源化小鼠中诱导清除戊型肝炎病毒

Gulce Sari, Claudia E Mulders, Jingting Zhu, Gertine W van Oord, Zongdi Feng, Jolanda J C Kreeft-Voermans, Andre Boonstra, Thomas Vanwolleghem

The Viral ORF3 Protein Is Required for Hepatitis E Virus Apical Release and Efficient Growth in Polarized Hepatocytes and Humanized Mice

病毒 ORF3 蛋白是戊型肝炎病毒顶端释放和极化肝细胞和人源化小鼠中有效生长所必需的

Gulce Sari #, Jingting Zhu #, Charuta Ambardekar, Xin Yin, Andre Boonstra, Zongdi Feng, Thomas Vanwolleghem

Interferon-alpha treatment rapidly clears Hepatitis E virus infection in humanized mice

干扰素α治疗迅速清除人源化小鼠的戊型肝炎病毒感染

Martijn D B van de Garde, Suzan D Pas, Gertine W van Oord, Lucio Gama, Youkyung Choi, Robert A de Man, Andre Boonstra, Thomas Vanwolleghem

Immunological Analysis During Interferon-Free Therapy for Chronic Hepatitis C Virus Infection Reveals Modulation of the Natural Killer Cell Compartment

慢性丙型肝炎病毒感染无干扰素治疗期间的免疫学分析揭示了自然杀伤细胞区的调节

Michelle Spaan, Gertine van Oord, Kim Kreefft, Jun Hou, Bettina E Hansen, Harry L A Janssen, Robert J de Knegt, Andre Boonstra

Hepatitis E Virus (HEV) Genotype 3 Infection of Human Liver Chimeric Mice as a Model for Chronic HEV Infection

戊型肝炎病毒 (HEV) 基因型 3 感染人肝嵌合小鼠作为慢性 HEV 感染的模型

Martijn D B van de Garde, Suzan D Pas, Guido van der Net, Robert A de Man, Albert D M E Osterhaus, Bart L Haagmans, Andre Boonstra, Thomas Vanwolleghem

Liver Monocytes and Kupffer Cells Remain Transcriptionally Distinct during Chronic Viral Infection

慢性病毒感染期间肝单核细胞和库普弗细胞在转录上保持独特性

Martijn D B van de Garde, Dowty Movita, Marieke van der Heide, Florence Herschke, Sandra De Jonghe, Lucio Gama, Andre Boonstra, Thomas Vanwolleghem

Frequencies of Circulating MAIT Cells Are Diminished in Chronic HCV, HIV and HCV/HIV Co-Infection and Do Not Recover during Therapy

慢性 HCV、HIV 和 HCV/HIV 合并感染中循环 MAIT 细胞频率减少,且在治疗期间无法恢复

Michelle Spaan, Sebastiaan J Hullegie, Boris J B Beudeker, Kim Kreefft, Gertine W van Oord, Zwier M A Groothuismink, Marjolein van Tilborg, Bart Rijnders, Robert J de Knegt, Mark A A Claassen, Andre Boonstra

Inflammatory monocytes recruited to the liver within 24 hours after virus-induced inflammation resemble Kupffer cells but are functionally distinct

病毒诱发炎症后 24 小时内募集到肝脏的炎症单核细胞类似于库普弗细胞,但功能不同

Dowty Movita, Martijn D B van de Garde, Paula Biesta, Kim Kreefft, Bart Haagmans, Elina Zuniga, Florence Herschke, Sandra De Jonghe, Harry L A Janssen, Lucio Gama, Andre Boonstra, Thomas Vanwolleghem