日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SOX17 Deficiency Mediates Pulmonary Hypertension: At the Crossroads of Sex, Metabolism, and Genetics

SOX17 缺乏导致肺动脉高压:性别、代谢和遗传学的交叉点

Shreya Sangam, Xutong Sun, Tae-Hwi Schwantes-An, Manivannan Yegambaram, Qing Lu, Yinan Shi, Todd Cook, Amanda Fisher, Andrea L Frump, Anna Coleman, Yanan Sun, Shuxin Liang, Howard Crawford, Katie A Lutz, Avinash D Maun, Michael W Pauciulo, Jason H Karnes, Ketul R Chaudhary, Duncan J Stewart, Paul R

Estrogen receptor-α prevents right ventricular diastolic dysfunction and fibrosis in female rats

雌激素受体-α 预防雌性大鼠右心室舒张功能障碍和纤维化

Tik-Chee Cheng, Jennifer L Philip, Diana M Tabima, Santosh Kumari, Bakhtiyor Yakubov, Andrea L Frump, Timothy A Hacker, Alessandro Bellofiore, Rongbo Li, Xin Sun, Kara N Goss, Tim Lahm, Naomi C Chesler

Isolated heart model demonstrates evidence of contractile and diastolic dysfunction in right ventricles from rats with sugen/hypoxia-induced pulmonary hypertension

离体心脏模型显示患有苏根/缺氧诱发的肺动脉高压的大鼠的右心室存在收缩和舒张功能障碍

Evandro M Neto-Neves, Andrea L Frump, Alexandra Vayl, Jeffrey A Kline, Tim Lahm

Estrogen receptor-dependent attenuation of hypoxia-induced changes in the lung genome of pulmonary hypertension rats

雌激素受体依赖性减弱缺氧引起的肺动脉高压大鼠肺基因组变化

Andrea L Frump, Marjorie E Albrecht, Jeanette N McClintick, Tim Lahm

17β-Estradiol mediates superior adaptation of right ventricular function to acute strenuous exercise in female rats with severe pulmonary hypertension

17β-雌二醇介导重度肺动脉高压雌性大鼠右心室功能对急性剧烈运动的良好适应

Tim Lahm, Andrea L Frump, Marjorie E Albrecht, Amanda J Fisher, Todd G Cook, Thomas J Jones, Bakhtiyor Yakubov, Jordan Whitson, Robyn K Fuchs, Aiping Liu, Naomi C Chesler, M Beth Brown

Genotype-phenotype effects of Bmpr2 mutations on disease severity in mouse models of pulmonary hypertension

Bmpr2 突变的基因型-表型对小鼠肺动脉高压模型中疾病严重程度的影响

Andrea L Frump, Arunima Datta, Sampa Ghose, James West, Mark P de Caestecker

Heterozygous null bone morphogenetic protein receptor type 2 mutations promote SRC kinase-dependent caveolar trafficking defects and endothelial dysfunction in pulmonary arterial hypertension

杂合的骨形态发生蛋白受体 2 型突变促进 SRC 激酶依赖性洞穴运输缺陷和肺动脉高压中的内皮功能障碍

Allison R Prewitt, Sampa Ghose, Andrea L Frump, Arumima Datta, Eric D Austin, Anne K Kenworthy, Mark P de Caestecker

Estradiol improves right ventricular function in rats with severe angioproliferative pulmonary hypertension: effects of endogenous and exogenous sex hormones

雌二醇改善重度血管增生性肺动脉高压大鼠的右心室功能:内源性和外源性激素的影响

Andrea L Frump, Kara N Goss, Alexandra Vayl, Marjorie Albrecht, Amanda Fisher, Roziya Tursunova, John Fierst, Jordan Whitson, Anthony R Cucci, M Beth Brown, Tim Lahm

Abnormal trafficking of endogenously expressed BMPR2 mutant allelic products in patients with heritable pulmonary arterial hypertension

遗传性肺动脉高压患者内源性表达的 BMPR2 突变等位基因产物的异常运输

Andrea L Frump, Jonathan W Lowery, Rizwan Hamid, Eric D Austin, Mark de Caestecker

ID family protein expression and regulation in hypoxic pulmonary hypertension

缺氧性肺动脉高压中ID家族蛋白的表达与调节

Jonathan W Lowery, Andrea L Frump, Lynda Anderson, Gabriella E DiCarlo, Mark T Jones, Mark P de Caestecker