De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
从头嘧啶合成是IDH突变型胶质瘤的一个可靶向弱点。
期刊:Cancer Cell
影响因子:48.8
doi:10.1016/j.ccell.2022.07.011
Diana D Shi ,Milan R Savani ,Michael M Levitt ,Adam C Wang ,Jennifer E Endress ,Cylaina E Bird ,Joseph Buehler ,Sylwia A Stopka ,Michael S Regan ,Yu-Fen Lin ,Vinesh T Puliyappadamba ,Wenhua Gao ,Januka Khanal ,Laura Evans ,Joyce H Lee ,Lei Guo ,Yi Xiao ,Min Xu ,Bofu Huang ,Rebecca B Jennings ,Dennis M Bonal ,Misty S Martin-Sandoval ,Tammie Dang ,Lauren C Gattie ,Amy B Cameron ,Sungwoo Lee ,John M Asara ,Harley I Kornblum ,Tak W Mak ,Ryan E Looper ,Quang-De Nguyen ,Sabina Signoretti ,Stefan Gradl ,Andreas Sutter ,Michael Jeffers ,Andreas Janzer ,Mark A Lehrman ,Lauren G Zacharias ,Thomas P Mathews ,Julie-Aurore Losman ,Timothy E Richardson ,Daniel P Cahill ,Ralph J DeBerardinis ,Keith L Ligon ,Lin Xu ,Peter Ly ,Nathalie Y R Agar ,Kalil G Abdullah ,Isaac S Harris ,William G Kaelin Jr ,Samuel K McBrayer
