Andreas Tholey相关文献与解析，生知库 | 链接生命科学的每一步

Kira Bickenbach, Nele David, Tomas Koudelka, Corentin Joos, Franka Scharfenberg, Malina Rüffer, Fred Armbrust, Dimitris Georgiadis, Fabrice Beau, Lea Stahmer, Sascha Rahn, Andreas Tholey, Claus Pietrzik, Christoph Becker-Pauly

肿瘤

发表日期：2025

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Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation

PLD3 的结构分析揭示了溶酶体 5' 外切酶介导的核酸降解机制

期刊:Nucleic Acids Research

影响因子:16.6

doi:10.1093/nar/gkad1114

Yvette Roske, Cedric Cappel, Nils Cremer, Patrick Hoffmann, Tomas Koudelka, Andreas Tholey, Udo Heinemann, Oliver Daumke, Markus Damme

信号转导

发表日期：2024

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Uncovering the small proteome of Methanosarcina mazei using Ribo-seq and peptidomics under different nitrogen conditions

在不同氮条件下利用 Ribo-seq 和肽组学揭示甲烷八叠球菌的小蛋白质组

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-024-53008-8

Muhammad Aammar Tufail, Britta Jordan, Lydia Hadjeras, Rick Gelhausen, Liam Cassidy, Tim Habenicht, Miriam Gutt, Lisa Hellwig, Rolf Backofen, Andreas Tholey, Cynthia M Sharma, Ruth A Schmitz

微生物学

发表日期：2024

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Combining systems and synthetic biology for in vivo enzymology

将系统与合成生物学相结合用于体内酶学

期刊:EMBO Journal

影响因子:9.4

doi:10.1038/s44318-024-00251-w

Sara Castaño-Cerezo, Alexandre Chamas, Hanna Kulyk, Christian Treitz, Floriant Bellvert, Andreas Tholey, Virginie Galéote, Carole Camarasa, Stéphanie Heux, Luis F Garcia-Alles, Pierre Millard, Gilles Truan0

发表日期：2024

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Human APOE4 Protects High-Fat and High-Sucrose Diet Fed Targeted Replacement Mice against Fatty Liver Disease Compared to APOE3

与 APOE3 相比，人类 APOE4 可保护高脂肪和高蔗糖饮食喂养的靶向替代小鼠免于脂肪肝疾病

期刊:Aging and Disease

影响因子:7

doi:10.14336/AD.2023.0530

Patricia Huebbe, Stephanie Bilke, Johanna Rueter, Anke Schloesser, Graeme Campbel, Claus-C Glüer, Ralph Lucius, Christoph Röcken, Andreas Tholey, Gerald Rimbach

Analysis of Cytotoxic Granules and Constitutively Produced Extracellular Vesicles from Large Granular Lymphocytic Leukemia Cell Lines

大颗粒淋巴细胞白血病细胞系的细胞毒颗粒和组成性产生的细胞外囊泡的分析

期刊:Cells

影响因子:5.1

doi:10.3390/cells13161310

Lara Ploeger, Patrick Kaleja, Andreas Tholey, Marcus Lettau, Ottmar Janssen

Readdressing the Localization of Apolipoprotein E (APOE) in Mitochondria-Associated Endoplasmic Reticulum (ER) Membranes (MAMs): An Investigation of the Hepatic Protein-Protein Interactions of APOE with the Mitochondrial Proteins Lon Protease (LONP1), Mitochondrial Import Receptor Subunit TOM40 (TOMM40) and Voltage-Dependent Anion-Selective Channel 1 (VDAC1)

重新定位载脂蛋白 E (APOE) 在线粒体相关内质网 (ER) 膜 (MAM) 中的定位：研究 APOE 与线粒体蛋白 Lon 蛋白酶 (LONP1)、线粒体输入受体亚基 TOM40 (TOMM40) 和电压依赖性阴离子选择性通道 1 (VDAC1) 的肝蛋白质-蛋白质相互作用

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms251910597

Johanna Rueter, Gerald Rimbach, Stephanie Bilke, Andreas Tholey, Patricia Huebbe

Proteolytic processing of galectin-3 by meprin metalloproteases is crucial for host-microbiome homeostasis

半乳糖凝集素-3经膜蛋白酶金属蛋白酶的蛋白水解加工对宿主-微生物群稳态至关重要。

期刊:Science Advances

影响因子:11.7

doi:10.1126/sciadv.adf4055

Cynthia Bülck ，Elisabeth E L Nyström ，Tomas Koudelka ，Michael Mannbar-Frahm ，Gerrit Andresen ，Mariem Radhouani ，Florian Tran ，Franka Scharfenberg ，Friederike Schrell ，Fred Armbrust ，Eileen Dahlke ，Bei Zhao ，Alex Vervaeke ，Franziska Theilig ，Philip Rosenstiel ，Philipp Starkl ，Stephan P Rosshart ，Helmut Fickenscher ，Andreas Tholey ，Gunnar C Hansson ，Christoph Becker-Pauly

微生物学

发表日期：2023

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Protease-independent control of parthanatos by HtrA2/Omi

HtrA2/Omi 对蛋白酶独立的控制

期刊:Cellular and Molecular Life Sciences

影响因子:6.2

doi:10.1007/s00018-023-04904-7

Jonas Weiß, Michelle Heib, Thiemo Korn, Justus Hoyer, Johaiber Fuchslocher Chico, Susann Voigt, Tomas Koudelka, Andreas Tholey, Dieter Adam

信号转导

发表日期：2023

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The mitochondrial BCKD complex interacts with hepatic apolipoprotein E in cultured cells in vitro and mouse livers in vivo

线粒体 BCKD 复合物与体外培养细胞和小鼠体内肝脏中的肝载脂蛋白 E 相互作用

期刊:Cellular and Molecular Life Sciences

影响因子:6.2

doi:10.1007/s00018-023-04706-x

Johanna Rueter, Gerald Rimbach, Christian Treitz, Anke Schloesser, Kai Lüersen, Andreas Tholey, Patricia Huebbe

Targeted approach to determine the impact of cancer-associated protease variants

有针对性的方法来确定癌症相关蛋白酶变体的影响

Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation

PLD3 的结构分析揭示了溶酶体 5' 外切酶介导的核酸降解机制

Uncovering the small proteome of Methanosarcina mazei using Ribo-seq and peptidomics under different nitrogen conditions

在不同氮条件下利用 Ribo-seq 和肽组学揭示甲烷八叠球菌的小蛋白质组

Combining systems and synthetic biology for in vivo enzymology

将系统与合成生物学相结合用于体内酶学

Human APOE4 Protects High-Fat and High-Sucrose Diet Fed Targeted Replacement Mice against Fatty Liver Disease Compared to APOE3

与 APOE3 相比，人类 APOE4 可保护高脂肪和高蔗糖饮食喂养的靶向替代小鼠免于脂肪肝疾病

Analysis of Cytotoxic Granules and Constitutively Produced Extracellular Vesicles from Large Granular Lymphocytic Leukemia Cell Lines

大颗粒淋巴细胞白血病细胞系的细胞毒颗粒和组成性产生的细胞外囊泡的分析

重新定位载脂蛋白 E (APOE) 在线粒体相关内质网 (ER) 膜 (MAM) 中的定位：研究 APOE 与线粒体蛋白 Lon 蛋白酶 (LONP1)、线粒体输入受体亚基 TOM40 (TOMM40) 和电压依赖性阴离子选择性通道 1 (VDAC1) 的肝蛋白质-蛋白质相互作用

Proteolytic processing of galectin-3 by meprin metalloproteases is crucial for host-microbiome homeostasis

半乳糖凝集素-3经膜蛋白酶金属蛋白酶的蛋白水解加工对宿主-微生物群稳态至关重要。

Protease-independent control of parthanatos by HtrA2/Omi

HtrA2/Omi 对蛋白酶独立的控制

The mitochondrial BCKD complex interacts with hepatic apolipoprotein E in cultured cells in vitro and mouse livers in vivo

线粒体 BCKD 复合物与体外培养细胞和小鼠体内肝脏中的肝载脂蛋白 E 相互作用