日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation

IKZF2 驱动白血病干细胞自我更新并抑制髓系分化

Sun-Mi Park, Hyunwoo Cho, Angela M Thornton, Trevor S Barlowe, Timothy Chou, Sagar Chhangawala, Lauren Fairchild, James Taggart, Arthur Chow, Alexandria Schurer, Antoine Gruet, Matthew D Witkin, Jun Hyun Kim, Ethan M Shevach, Andrei Krivtsov, Scott A Armstrong, Christina Leslie, Michael G Kharas

TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells

TET蛋白保护人类胚胎干细胞中的二价启动子免受从头甲基化。

Nipun Verma # ,Heng Pan # ,Louis C Doré ,Abhijit Shukla ,Qing V Li ,Bobbie Pelham-Webb ,Virginia Teijeiro ,Federico González ,Andrei Krivtsov ,Chan-Jung Chang ,Eirini P Papapetrou ,Chuan He ,Olivier Elemento ,Danwei Huangfu

Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells

MSI2 相互作用蛋白的功能筛选确定了 SYNCRIP 在髓系白血病干细胞中的重要作用

Ly P Vu, Camila Prieto, Elianna M Amin, Sagar Chhangawala, Andrei Krivtsov, M Nieves Calvo-Vidal, Timothy Chou, Arthur Chow, Gerard Minuesa, Sun Mi Park, Trevor S Barlowe, James Taggart, Patrick Tivnan, Raquel P Deering, Lisa P Chu, Jeong-Ah Kwon, Cem Meydan, Javier Perales-Paton, Arora Arshi, Mitha

ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia

ASXL2 对造血至关重要,并且在白血病中作为单倍体不足的肿瘤抑制因子发挥作用。

Jean-Baptiste Micol ,Alessandro Pastore ,Daichi Inoue ,Nicolas Duployez ,Eunhee Kim ,Stanley Chun-Wei Lee ,Benjamin H Durham ,Young Rock Chung ,Hana Cho ,Xiao Jing Zhang ,Akihide Yoshimi ,Andrei Krivtsov ,Richard Koche ,Eric Solary ,Amit Sinha ,Claude Preudhomme ,Omar Abdel-Wahab

Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins

调节剪接催化作用以实现针对剪接体蛋白基因突变的白血病治疗

Stanley Chun-Wei Lee, Heidi Dvinge, Eunhee Kim, Hana Cho, Jean-Baptiste Micol, Young Rock Chung, Benjamin H Durham, Akihide Yoshimi, Young Joon Kim, Michael Thomas, Camille Lobry, Chun-Wei Chen, Alessandro Pastore, Justin Taylor, Xujun Wang, Andrei Krivtsov, Scott A Armstrong, James Palacino, Silvia

AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes

AF10 调节不同 AML 亚型中的进行性 H3K79 甲基化和 HOX 基因表达

Aniruddha J Deshpande, Anagha Deshpande, Amit U Sinha, Liying Chen, Jenny Chang, Ali Cihan, Maurizio Fazio, Chun-Wei Chen, Nan Zhu, Richard Koche, Liuda Dzhekieva, Gloria Ibáñez, Stuart Dias, Deepti Banka, Andrei Krivtsov, Minkui Luo, Robert G Roeder, James E Bradner, Kathrin M Bernt, Scott A Armstr