日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Bioluminescence imaging of Cyp1a1-luciferase reporter mice demonstrates prolonged activation of the aryl hydrocarbon receptor in the lung

Cyp1a1-荧光素酶报告基因小鼠的生物发光成像显示肺部芳烃受体持续激活

Nicolas Veland # ,Hannah J Gleneadie # ,Karen E Brown ,Alessandro Sardini ,Joaquim Pombo ,Andrew Dimond ,Vanessa Burns ,Karen Sarkisyan ,Chris Schiering ,Zoe Webster ,Matthias Merkenschlager ,Amanda G Fisher

Protein restriction during pregnancy alters Cdkn1c silencing, dopamine circuitry and offspring behaviour without changing expression of key neuronal marker genes

怀孕期间的蛋白质限制会改变 Cdkn1c 沉默、多巴胺回路和后代行为,而不会改变关键神经元标记基因的表达

Chiara Prodani, Elaine E Irvine, Alessandro Sardini, Hannah J Gleneadie, Andrew Dimond, Mathew Van de Pette, Rosalind John, Michelle Kokkinou, Oliver Howes, Dominic J Withers, Mark A Ungless, Matthias Merkenschlager, Amanda G Fisher

Loss of H3K9 trimethylation alters chromosome compaction and transcription factor retention during mitosis

H3K9 三甲基化的缺失会改变有丝分裂过程中染色体的压缩和转录因子的保留

Dounia Djeghloul, Andrew Dimond, Sherry Cheriyamkunnel, Holger Kramer, Bhavik Patel, Karen Brown, Alex Montoya, Chad Whilding, Yi-Fang Wang, Matthias E Futschik, Nicolas Veland, Thomas Montavon, Thomas Jenuwein, Matthias Merkenschlager, Amanda G Fisher

Endogenous bioluminescent reporters reveal a sustained increase in utrophin gene expression upon EZH2 and ERK1/2 inhibition

内源性生物发光报告基因显示,EZH2 和 ERK1/2 抑制后,utrophin 基因表达持续增加

Hannah J Gleneadie #, Beatriz Fernandez-Ruiz #, Alessandro Sardini, Mathew Van de Pette, Andrew Dimond, Rab K Prinjha, James McGinty, Paul M W French, Hakan Bagci, Matthias Merkenschlager, Amanda G Fisher

Drug-induced loss of imprinting revealed using bioluminescent reporters of Cdkn1c

使用 Cdkn1c 的生物发光报告基因揭示药物引起的印迹丧失

Andrew Dimond, Mathew Van de Pette, Victoria Taylor-Bateman, Karen Brown, Alessandro Sardini, Chad Whilding, Amelie Feytout, Rab K Prinjha, Matthias Merkenschlager, Amanda G Fisher

Epigenetic changes induced by in utero dietary challenge result in phenotypic variability in successive generations of mice

子宫内饮食挑战诱导的表观遗传变化导致小鼠后代表型变异。

Mathew Van de Pette,Andrew Dimond #,António M Galvão #,Steven J Millership,Wilson To,Chiara Prodani,Gráinne McNamara,Ludovica Bruno,Alessandro Sardini,Zoe Webster,James McGinty,Paul M W French,Anthony G Uren,Juan Castillo-Fernandez,William Watkinson,Anne C Ferguson-Smith,Matthias Merkenschlager,Rosalind M John,Gavin Kelsey,Amanda G Fisher

Identifying proteins bound to native mitotic ESC chromosomes reveals chromatin repressors are important for compaction

识别与天然有丝分裂 ESC 染色体结合的蛋白质,揭示染色质阻遏物对压缩很重要

Dounia Djeghloul, Bhavik Patel, Holger Kramer, Andrew Dimond, Chad Whilding, Karen Brown, Anne-Céline Kohler, Amelie Feytout, Nicolas Veland, James Elliott, Tanmay A M Bharat, Abul K Tarafder, Jan Löwe, Bee L Ng, Ya Guo, Jacky Guy, Miles K Huseyin, Robert J Klose, Matthias Merkenschlager, Amanda G F

Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells

基因组组织和染色质分析表明胰岛素样生长因子信号的转录下调是发育中的 B 细胞衰老的标志

Hashem Koohy, Daniel J Bolland, Louise S Matheson, Stefan Schoenfelder, Claudia Stellato, Andrew Dimond, Csilla Várnai, Peter Chovanec, Tamara Chessa, Jeremy Denizot, Raquel Manzano Garcia, Steven W Wingett, Paula Freire-Pritchett, Takashi Nagano, Phillip Hawkins, Len Stephens, Sarah Elderkin, Mikha

Allele-specific control of replication timing and genome organization during development

发育过程中等位基因特异性控制复制时间和基因组组织

Juan Carlos Rivera-Mulia, Andrew Dimond, Daniel Vera, Claudia Trevilla-Garcia, Takayo Sasaki, Jared Zimmerman, Catherine Dupont, Joost Gribnau, Peter Fraser, David M Gilbert

Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome

多梳抑制复合物 PRC1 在空间上限制小鼠胚胎干细胞基因组

Stefan Schoenfelder #, Robert Sugar #, Andrew Dimond #, Biola-Maria Javierre #, Harry Armstrong #, Borbala Mifsud, Emilia Dimitrova, Louise Matheson, Filipe Tavares-Cadete, Mayra Furlan-Magaril, Anne Segonds-Pichon, Wiktor Jurkowski, Steven W Wingett, Kristina Tabbada, Simon Andrews, Bram Herman, Em