日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

In Silico Studies and Biological Evaluation of Thiosemicarbazones as Cruzain-Targeting Trypanocidal Agents for Chagas Disease

利用计算机模拟研究和生物学评价硫代氨基脲类化合物作为靶向克鲁赞锥虫的锥虫杀灭剂治疗恰加斯病

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics18010065
Meier, Lidiane; de Melo, Milena F C V; Abreu, Heitor R; Oliveira, Isabella M E; Sens, Larissa; Doring, Thiago H; Krogh, Renata; Beatriz, Adilson; Andricopulo, Adriano D; Saba, Sumbal; de Oliveira, Aldo S; Rafique, Jamal
发表日期：2026
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Multiscale-Aware Graph Embedding Approach Uncovers LC-61, a Potent Anti-Leishmania infantum Compound

多尺度感知图嵌入方法揭示了LC-61，一种强效抗婴儿利什曼原虫化合物。

期刊:Journal of Chemical Information and Modeling
影响因子:5.3
doi:10.1021/acs.jcim.5c02947
Costa, Vinícius Alexandre Fiaia; Carvalho, Alexandra Maria Dos Santos; Chelucci, Rafael Consolin; Mendonça de Melo, Felipe da Silva; Felizardo, Gustavo Santos Sandes; Bernardes, Clarissa Alves Carneiro; Martin, Holli-Joi; Braga, Rodolpho de Campos; Charneau, Sébastien; Muratov, Eugene N; Andricopulo, Adriano Defini; Bastos, Izabela Marques Dourado; Neves, Bruno Junior
发表日期：2026
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Discovery and Early Optimization of 1H-Indole-2-carboxamides with Anti-Trypanosoma cruzi Activity

发现并早期优化具有抗克氏锥虫活性的1H-吲哚-2-甲酰胺类化合物

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.4c02942
de Oliveira, Ramon G; Cruz, Luiza R; Dessoy, Marco A; Koovits, Paul J; Dos Santos, Deborah A; de Oliveira, Luiz F N; Ferreira, Rafael A; Mollo, María C; Lee, Eun; Duarte, Simone M; Krogh, Renata; Ferreira, Leonardo L G; Chelucci, Rafael C; Dichiara, Maria; Simpson, Quillon J; Feltrin, Clarissa; da Silva, Adriana C; Dos Santos, Benedito M; Broering, Milena F; Pollastri, Michael P; Ferrins, Lori; Moraes, Carolina B; Andricopulo, Adriano D; Kratz, Jadel M; Sjö, Peter; Mowbray, Charles E; Dias, Luiz C
发表日期：2025
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Phenotypic Screening of H(1)-Antihistamines Identifies Promethazine and Rupatadine as Active Compounds Against Toxocara canis Infective Larvae

表型筛选H(1)抗组胺药，发现异丙嗪和卢帕他定对犬弓蛔虫感染性幼虫具有活性

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph18070997
Silva, Taís C; Godoy-Silva, Julia; Amaro, Monique C; Silva-Silva, João V; Doring, Thiago H; Ferreira, Leonardo L G; Andricopulo, Adriano D; de Moraes, Josué
炎症/感染
发表日期：2025
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Screening of Medicines for Malaria Venture Open Boxes Identifies Potent SARS-CoV‑2 Papain-like Protease (PL(pro)) Inhibitors

疟疾药物筛选项目“开放盒子”发现了强效的SARS-CoV-2木瓜蛋白酶样蛋白酶（PL(pro)）抑制剂

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.5c04858
Gawriljuk, Victor Oliveira; Noske, Gabriela Dias; Fernandes, Rafaela Sachetto; Nakamura, Aline Minalli; Freire, Marjorie C L C; Godoy, Mariana Ortiz; Bonatto, Vinicius; Chelucci, Rafael; Andricopulo, Adriano; Bakowski, Malina A; Wolff, Karen C; Riva, Laura; Burrows, Jeremy N; Wells, Timothy N C; Laleu, Benoît; Martins, Ronaldo; Souza, Juliano Paula; Arruda, Eurico; Samby, Kirandeep; Laskar, Sujay; Guido, Rafael Victorio Carvalho; Oliva, Glaucius; Godoy, Andre Schutzer
微生物学
疟疾
SARS-CoV-2
发表日期：2025
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Hit-to-Lead Studies of Pyrazinylpiperazines against Visceral Leishmaniasis: Pharmacokinetic Profile and In Vivo Efficacy of Potent Compounds against Leishmania infantum.

吡嗪基哌嗪类化合物对内脏利什曼病的先导化合物研究：强效化合物对婴儿利什曼原虫的药代动力学特征和体内疗效

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.5c00318
Jacques Dit Lapierre Thibault Joseph William, Gabriela Faleiro de Moura Lodi Cruz Mariza, Barbosa Gisele, Costa Analu R, Chávez-Fumagalli Miguel Angel, Froes Thamires Quadros, Ramos Priscila Zonzini, Macruz Paula Derksen, Carolyne Souza Trindade Thalita, Pilau Eduardo Jorge, Sampaio Tavares Veras Patricia, Nonato Maria Cristina, Massirer Katlin B, Ferreira Leonardo L G, Andricopulo Adriano D, Lima Lídia Moreira, Murta Silvane Maria Fonseca, Rezende Júnior Celso de Oliveira
其它
发表日期：2025
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Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease-Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

从富含蛋白酶的水果中分离的镰刀菌和土曲霉的生物活性代谢物研究：抗真菌、抗锥虫和酶抑制活性

期刊:Chemistry & Biodiversity
影响因子:2.5
doi:10.1002/cbdv.202500673
de Oliveira Almeida, Gabriela; Mazucato, Vitor de Souza; Tonani, Ludmilla; von Zeska Kress, Marcia Regina; Barbosa, Gisele; Krogh, Renata; Andricopulo, Adriano Defini; Gomes Ferreira, Leonardo Luiz; Vieira, Paulo Cezar
微生物学
代谢
发表日期：2025
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Co-cultivation and Medium Optimization: A Strategy for Discovering Fungal-derived Protease Inhibitors

共培养和培养基优化：发现真菌来源蛋白酶抑制剂的策略

期刊:Chemistry & Biodiversity
影响因子:2.5
doi:10.1002/cbdv.202501135
Mazucato, Vitor de Souza; Tonani, Ludmilla; von Zeska Kress, Marcia Regina; Andricopulo, Adriano Defini; Barbosa, Gisele; Krogh, Renata; Gomes Ferreira, Leonardo Luiz; Vieira, Paulo Cezar
微生物学
发表日期：2025
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Latin American Natural Product Database (LANaPDB): An Update

拉丁美洲天然产物数据库（LANaPDB）：最新进展

期刊:Journal of Chemical Information and Modeling
影响因子:5.3
doi:10.1021/acs.jcim.4c01560
Gómez-García, Alejandro; Acuña Jiménez, Daniel A; Zamora, William J; Barazorda-Ccahuana, Haruna L; Chávez-Fumagalli, Miguel Á; Valli, Marilia; Andricopulo, Adriano D; Bolzani, Vanderlan da S; Olmedo, Dionisio A; Solís, Pablo N; Núñez, Marvin J; Rodríguez Pérez, Johny R; Valencia Sánchez, Hoover A; Cortés Hernández, Héctor F; Mosquera Martinez, Oscar M; Medina-Franco, José L
发表日期：2024
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Neglected Tropical Diseases: A Chemoinformatics Approach for the Use of Biodiversity in Anti-Trypanosomatid Drug Discovery

被忽视的热带病：利用生物多样性进行抗锥虫药物发现的化学信息学方法

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom14081033
Valli, Marilia; Döring, Thiago H; Marx, Edgard; Ferreira, Leonardo L G; Medina-Franco, José L; Andricopulo, Adriano D
发表日期：2024
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