日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

First-in-class anti-human CD45RC antibody targets CD45RC(high) T and B cells to mitigate pathogenic immune responses

首创的抗人CD45RC抗体靶向CD45RC(high) T细胞和B细胞,以减轻致病性免疫反应。

Bergua, Cécile; Ahmil-Boiteau, Ghenima; Ouisse, Laure-Hélène; Vimond, Nadège; Sérazin, Céline; Dugast, Lisa; Humeau, Romain; Salama, Apolline; Tesson, Laurent; Swinnen, Katleen; Van Brempt, Ronald; Collette, Alexis; Anegon, Ignacio; Guillonneau, Carole

Inactivation of the Phosphatase Activity of Soluble Epoxide Hydrolase Modulates SIRT3 and Attenuates Experimental Pulmonary Hypertension

可溶性环氧化物水解酶磷酸酶活性的失活调节SIRT3并减轻实验性肺动脉高压

Leuillier, Matthieu; Chelgham, Mustapha; Messaoudi, Hind; Tu, Ly; Ménoret, Severine; Thuillet, Raphaël; Groussard, Déborah; Lillich, Felix F; Ottaviani, Mina; Nicol, Lionel; Mulder, Paul; Humbert, Marc; Richard, Vincent; Anegon, Ignacio; Morisseau, Christophe; Proschak, Ewgenij; Guignabert, Christophe; Bellien, Jérémy

The phosphatase activity of soluble epoxide hydrolase regulates vascular calcification through the metabolism of pyrophosphate anions

可溶性环氧化物水解酶的磷酸酶活性通过焦磷酸根阴离子的代谢来调节血管钙化。

Messaoudi, Hind; Varennes, Olivier; Berg, Elodie; Perzo, Nicolas; Renet, Sylvanie; Chegrani, Ghiles; Duflot, Thomas; Feugray, Guillaume; Lillich, Felix F; Kauffenstein, Gilles; Brunel, Valéry; Six, Isabelle; Mentaverri, Romuald; Richard, Vincent; Anegon, Ignacio; Morisseau, Christophe; Kamel, Saïd; Proschak, Ewgenij; Bellien, Jérémy

Bone morphogenetic protein-9 controls pulmonary vascular growth and remodeling

骨形态发生蛋白-9控制肺血管生长和重塑

Berrebeh, Nihel; Mbouamboua, Yvon; Thuillet, Raphaël; Ottaviani, Mina; Robert, Fabien; Kamel Chelgham, Mustapha; Magnone, Virginie; Desroches-Castan, Agnès; Ricard, Nicolas; Anegon, Ignacio; Remy, Séverine; Schermuly, Ralph Theo; Lebrigand, Kevin; Kojonazarov, Baktybek; Savale, Laurent; Humbert, Marc; Bailly, Sabine; Barbry, Pascal; Tu, Ly; Guignabert, Christophe

Phenotypic characterization of an Atp13a2 knockout rat model of Parkinson's disease.

帕金森病 Atp13a2 基因敲除大鼠模型的表型特征分析。

Kinet Rémi, Sikora Joanna, Arotcarena Marie-Laure, Decourt Melina, Balado Eric, Doudnikoff Evelyne, Bohic Sylvain, Vesnaver Marta, Lovisotto Anna, Thiolat Marie-Laure, Dutheil Nathalie, Mazzocco Claire, Harhouri Karim, Steinschneider Rémy, Menoret Severine, Tesson Laurent, Anegon Ignacio, Morari Michele, Vila Miquel, Georges François, Bezard Erwan, Fernagut Pierre-Olivier, Dehay Benjamin

Combination of Orai1 inhibitor CM5480 with specific therapy mitigates pulmonary hypertension and its cardiac dysfunction

Orai1抑制剂CM5480联合特定疗法可减轻肺动脉高压及其心脏功能障碍

Willer, Anaïs Saint-Martin; Ruffenach, Grégoire; Masson, Bastien; El Jekmek, Kristelle; Boët, Angèle; Adão, Rui; Gourmelon, Mathieu; Beauvais, Antoine; Sabourin, Jessica; Dutheil, Mary; Ghigna, Maria-Rosa; Tesson, Laurent; Ménoret, Séverine; Anegon, Ignacio; Bauer, Fabrice; de Montpréville, Vincent; Hebbar, Sudarshan; Brás-Silva, Carmen; Stauderman, Kenneth; Humbert, Marc; Mercier, Olaf; Montani, David; Capuano, Véronique; Antigny, Fabrice

Human pluripotent stem cell-derived hepatic progenitors exhibit a partially hypoimmunogenic phenotype and actively inhibit immune responses

人多能干细胞来源的肝脏祖细胞表现出部分低免疫原性表型,并能主动抑制免疫反应。

Gantier, Malika; Ménoret, Séverine; Fourrier, Angélique; Delbos, Frédéric; Nguyen, Tuan Huy; Anegon, Ignacio

Generation of a compound heterozygous ABCA4 rat model with pathological features of STGD1.

构建具有 STGD1 病理特征的复合杂合子 ABCA4 大鼠模型

Morival Clément, Croyal Mikaël, Remy Séverine, Mortier Elodie, Libeau Lyse, Veziers Joëlle, Provost Nathalie, Demilly Joanna, Mendes-Madeira Alexandra, Isiegas Carolina, Tesson Laurent, Anegon Ignacio, Adjali Oumeya, Cronin Therese

Engineering Large-Scale and Innervated Functional Human Gut for Transplantation

构建用于移植的大规模、神经支配的功能性人类肠道

Poling, Holly M; Noël, Théo; Singh, Akaljot; Fisher, Garrett W; Thorner, Konrad; Chaturvedi, Praneet; Nattamai, Kalpana; Srivastava, Kalpana; Batie, Matthew R; Hausfeld, Taylor; Pitstick, Amy L; Ménoret, Séverine; Anegon, Ignacio; Barrile, Riccardo; Mayhew, Christopher N; Takebe, Takanori; Wells, James M; Helmrath, Michael A; Mahe, Maxime M

Can Humanized Immune System Mouse and Rat Models Accelerate the Development of Cytomegalovirus-Based Vaccines Against Infectious Diseases and Cancers?

人源化免疫系统小鼠和大鼠模型能否加速基于巨细胞病毒的传染病和癌症疫苗的研发?

Craft, Kaci; Amanor, Athina; Barnett, Ian; Donaldson, Clarke; Anegon, Ignacio; Madduri, Srinivas; Tang, Qiyi; Bility, Moses T