Angela D Bhalla相关文献与解析，生知库 | 链接生命科学的每一步

Co-targeting PI3K, mTOR, and IGF1R with small molecule inhibitors for treating undifferentiated pleomorphic sarcoma

PI3K、mTOR 和 IGF1R 与小分子抑制剂联合治疗未分化多形性肉瘤

doi:10.1080/15384047.2017.1373230

Caitlin D May, Sharon M Landers, Svetlana Bolshakov, XiaoYan Ma, Davis R Ingram, Christine M Kivlin, Kelsey L Watson, Ghadah A Al Sannaa, Angela D Bhalla, Wei-Lien Wang, Alexander J Lazar, Keila E Torres

Deep sequencing of mitochondrial genomes reveals increased mutation load in Friedreich's ataxia

线粒体基因组的深度测序揭示了弗里德赖希共济失调症中的突变负荷增加

期刊:Annals of Clinical and Translational Neurology

影响因子:4.4

doi:10.1002/acn3.322

Angela D Bhalla, Alireza Khodadadi-Jamayran, Yanjie Li, David R Lynch, Marek Napierala

细胞生物学

发表日期：2016

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Establishment and Maintenance of Primary Fibroblast Repositories for Rare Diseases-Friedreich's Ataxia Example

罕见疾病原代成纤维细胞库的建立与维护-弗里德赖希共济失调症示例

期刊:Biopreservation and Biobanking

影响因子:

doi:10.1089/bio.2015.0117

Yanjie Li, Urszula Polak, Amanda D Clark, Angela D Bhalla, Yu-Yun Chen, Jixue Li, Jennifer Farmer, Lauren Seyer, David Lynch, Jill S Butler, Marek Napierala

Excision of Expanded GAA Repeats Alleviates the Molecular Phenotype of Friedreich's Ataxia

切除扩增的 GAA 重复序列可减轻弗里德赖希共济失调的分子表型

期刊:Molecular Therapy

影响因子:12.1

doi:10.1038/mt.2015.41

Yanjie Li, Urszula Polak, Angela D Bhalla, Natalia Rozwadowska, Jill Sergesketter Butler, David R Lynch, Sharon Y R Dent, Marek Napierala

信号转导

发表日期：2015

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Expanded GAA repeats impede transcription elongation through the FXN gene and induce transcriptional silencing that is restricted to the FXN locus

扩增的 GAA 重复序列阻碍了 FXN 基因的转录延长，并诱导了仅限于 FXN 位点的转录沉默

期刊:Human Molecular Genetics

影响因子:3.1

doi:10.1093/hmg/ddv397

Yanjie Li, Yue Lu, Urszula Polak, Kevin Lin, Jianjun Shen, Jennifer Farmer, Lauren Seyer, Angela D Bhalla, Natalia Rozwadowska, David R Lynch, Jill Sergesketter Butler, Marek Napierala

信号转导

发表日期：2015

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AXL Inhibition Enhances MEK Inhibitor Sensitivity in Malignant Peripheral Nerve Sheath Tumors

AXL 抑制可增强恶性周围神经鞘瘤对 MEK 抑制剂的敏感性

Co-targeting PI3K, mTOR, and IGF1R with small molecule inhibitors for treating undifferentiated pleomorphic sarcoma

PI3K、mTOR 和 IGF1R 与小分子抑制剂联合治疗未分化多形性肉瘤

Deep sequencing of mitochondrial genomes reveals increased mutation load in Friedreich's ataxia

线粒体基因组的深度测序揭示了弗里德赖希共济失调症中的突变负荷增加

Establishment and Maintenance of Primary Fibroblast Repositories for Rare Diseases-Friedreich's Ataxia Example

罕见疾病原代成纤维细胞库的建立与维护-弗里德赖希共济失调症示例

Excision of Expanded GAA Repeats Alleviates the Molecular Phenotype of Friedreich's Ataxia

切除扩增的 GAA 重复序列可减轻弗里德赖希共济失调的分子表型

Expanded GAA repeats impede transcription elongation through the FXN gene and induce transcriptional silencing that is restricted to the FXN locus

扩增的 GAA 重复序列阻碍了 FXN 基因的转录延长，并诱导了仅限于 FXN 位点的转录沉默